Carotenoid as a potential antioxidant marker for schizophrenia

Free radicals are results of aerobic activities and can damage cells when present in excess by causing oxidative stress. Antioxidants efficiently quench free radicals to counteract oxidative stress. Carotenoids are antioxidants that have detectable natural colorant which can be measured as indicator...

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Main Authors:	Chow, T.J, Loh, H.C
Format:	Article
Language:	English
Published:	Universiti Kebangsaan Malaysia 2012
Online Access:	http://journalarticle.ukm.my/4858/ http://journalarticle.ukm.my/4858/ http://journalarticle.ukm.my/4858/1/08%2520T.J.%2520Chow.pdf

id	ukm-4858
recordtype	eprints
spelling	ukm-48582016-12-14T06:37:08Z http://journalarticle.ukm.my/4858/ Carotenoid as a potential antioxidant marker for schizophrenia Chow, T.J Loh, H.C Free radicals are results of aerobic activities and can damage cells when present in excess by causing oxidative stress. Antioxidants efficiently quench free radicals to counteract oxidative stress. Carotenoids are antioxidants that have detectable natural colorant which can be measured as indicator of antioxidant level in human. The aim of this study is to investigate possible association of carotenoid antioxidant levels in schizophrenia. A total of 524 patients with schizophrenia from Hospital Bahagia Ulu Kinta, Malaysia and 391 healthy controls were recruited. Subjects’ skin carotenoid levels were measured through a non-invasive approach using Raman spectroscopy. Patients with schizophrenia showed significant (p < 0.01) lower carotenoid level compared to healthy controls. Factors such as gender, age, subtypes, antipsychotic drug treatments, and duration of illness did not differ significantly among patients. It is concluded that patient with schizophrenia have low levels of carotenoid antioxidants and is suggested to experience higher level of oxidative stress compared to healthy individuals. Universiti Kebangsaan Malaysia 2012-06 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/4858/1/08%2520T.J.%2520Chow.pdf Chow, T.J and Loh, H.C (2012) Carotenoid as a potential antioxidant marker for schizophrenia. Sains Malaysiana, 41 (6). pp. 715-720. ISSN 0126-6039 http://www.ukm.my/jsm/contents.html
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	Free radicals are results of aerobic activities and can damage cells when present in excess by causing oxidative stress. Antioxidants efficiently quench free radicals to counteract oxidative stress. Carotenoids are antioxidants that have detectable natural colorant which can be measured as indicator of antioxidant level in human. The aim of this study is to investigate possible association of carotenoid antioxidant levels in schizophrenia. A total of 524 patients with schizophrenia from Hospital Bahagia Ulu Kinta, Malaysia and 391 healthy controls were recruited. Subjects’ skin carotenoid levels were measured through a non-invasive approach using Raman spectroscopy. Patients with schizophrenia showed significant (p < 0.01) lower carotenoid level compared to healthy controls. Factors such as gender, age, subtypes, antipsychotic drug treatments, and duration of illness did not differ significantly among patients. It is concluded that patient with schizophrenia have low levels of carotenoid antioxidants and is suggested to experience higher level of oxidative stress compared to healthy individuals.
format	Article
author	Chow, T.J Loh, H.C
spellingShingle	Chow, T.J Loh, H.C Carotenoid as a potential antioxidant marker for schizophrenia
author_facet	Chow, T.J Loh, H.C
author_sort	Chow, T.J
title	Carotenoid as a potential antioxidant marker for schizophrenia
title_short	Carotenoid as a potential antioxidant marker for schizophrenia
title_full	Carotenoid as a potential antioxidant marker for schizophrenia
title_fullStr	Carotenoid as a potential antioxidant marker for schizophrenia
title_full_unstemmed	Carotenoid as a potential antioxidant marker for schizophrenia
title_sort	carotenoid as a potential antioxidant marker for schizophrenia
publisher	Universiti Kebangsaan Malaysia
publishDate	2012
url	http://journalarticle.ukm.my/4858/ http://journalarticle.ukm.my/4858/ http://journalarticle.ukm.my/4858/1/08%2520T.J.%2520Chow.pdf
first_indexed	2023-09-18T19:42:43Z
last_indexed	2023-09-18T19:42:43Z
_version_	1777405697516896256

Carotenoid as a potential antioxidant marker for schizophrenia

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