Spinal anaesthesia with bupivacaine and intrathecal morphine versus combined spinal-epidural anaesthesia using bupivacaine and epidural infusion of bupivacaine plus fentanyl for postoperative analgesia after hip and knee arthroplasty.

This randomised single-blinded study was conducted to evaluate if there was any difference between spinal anaesthesia with hyperbaric bupivacaine 0.5% and intrathecal morphine 0.2mg and combined-spinal epidural using hyperbaric bupivacaine 0.5% with epidural infusion of bupivacaine 0.1% plus fentany...

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Main Authors:	Mohd Azizan G, Karis M, Noordin Y
Format:	Article
Language:	English
Published:	Department of Surgery, UKM Medical Centre 2013
Online Access:	http://journalarticle.ukm.my/6724/ http://journalarticle.ukm.my/6724/ http://journalarticle.ukm.my/6724/1/09-MS1117_%2846-53%29.pdf

id	ukm-6724
recordtype	eprints
spelling	ukm-67242016-12-14T06:42:01Z http://journalarticle.ukm.my/6724/ Spinal anaesthesia with bupivacaine and intrathecal morphine versus combined spinal-epidural anaesthesia using bupivacaine and epidural infusion of bupivacaine plus fentanyl for postoperative analgesia after hip and knee arthroplasty. Mohd Azizan G, Karis M, Noordin Y, This randomised single-blinded study was conducted to evaluate if there was any difference between spinal anaesthesia with hyperbaric bupivacaine 0.5% and intrathecal morphine 0.2mg and combined-spinal epidural using hyperbaric bupivacaine 0.5% with epidural infusion of bupivacaine 0.1% plus fentanyl 2.0μg/ml for 24 hours, postoperative analgesia following hip and knee arthroplasty, in terms of pain score and side effects (nausea, vomiting, pruritus and respiratory depression). Eighty patients ASA I or ASA II, aged between 18 to 75 years who underwent knee and hip arthroplasty of approximately 3-4 hours, duration were recruited. They were randomly allocated to one of two groups by using computer generated randomised numbers. The pain score during the postoperative period was evaluated using Visual Analogue Score (VAS pain score) and the side effects were documented and treated accordingly. Results showed that patients in Group 1 and Group 2 were comparable in terms of age, gender, height, weight and race. There was no statistical difference in VAS pain score between the two groups at all times intervals. However, patients in Group 1 had a higher incidence of nausea and pruritus than patients in Group 2. None of the patients in either group, experienced respiratory depression. Thus, it was concluded that both intrathecal morphine 0.2mg and epidural infusion of bupivacaine 0.1% plus fentanyl 2.0μg/ml were comparable in providing postoperative analgesia up to 24 hours following hip and knee arthroplasty. Nevertheless, the use of spinal morphine led to a higher incidence of side effects namely nausea and pruritus. Department of Surgery, UKM Medical Centre 2013-12 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/6724/1/09-MS1117_%2846-53%29.pdf Mohd Azizan G, and Karis M, and Noordin Y, (2013) Spinal anaesthesia with bupivacaine and intrathecal morphine versus combined spinal-epidural anaesthesia using bupivacaine and epidural infusion of bupivacaine plus fentanyl for postoperative analgesia after hip and knee arthroplasty. Journal of Surgical Academia, 3 (2). pp. 46-53. ISSN 2231-7481 http://jsurgacad.com/
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	This randomised single-blinded study was conducted to evaluate if there was any difference between spinal anaesthesia with hyperbaric bupivacaine 0.5% and intrathecal morphine 0.2mg and combined-spinal epidural using hyperbaric bupivacaine 0.5% with epidural infusion of bupivacaine 0.1% plus fentanyl 2.0μg/ml for 24 hours, postoperative analgesia following hip and knee arthroplasty, in terms of pain score and side effects (nausea, vomiting, pruritus and respiratory depression). Eighty patients ASA I or ASA II, aged between 18 to 75 years who underwent knee and hip arthroplasty of approximately 3-4 hours, duration were recruited. They were randomly allocated to one of two groups by using computer generated randomised numbers. The pain score during the postoperative period was evaluated using Visual Analogue Score (VAS pain score) and the side effects were documented and treated accordingly. Results showed that patients in Group 1 and Group 2 were comparable in terms of age, gender, height, weight and race. There was no statistical difference in VAS pain score between the two groups at all times intervals. However, patients in Group 1 had a higher incidence of nausea and pruritus than patients in Group 2. None of the patients in either group, experienced respiratory depression. Thus, it was concluded that both intrathecal morphine 0.2mg and epidural infusion of bupivacaine 0.1% plus fentanyl 2.0μg/ml were comparable in providing postoperative analgesia up to 24 hours following hip and knee arthroplasty. Nevertheless, the use of spinal morphine led to a higher incidence of side effects namely nausea and pruritus.
format	Article
author	Mohd Azizan G, Karis M, Noordin Y,
spellingShingle	Mohd Azizan G, Karis M, Noordin Y, Spinal anaesthesia with bupivacaine and intrathecal morphine versus combined spinal-epidural anaesthesia using bupivacaine and epidural infusion of bupivacaine plus fentanyl for postoperative analgesia after hip and knee arthroplasty.
author_facet	Mohd Azizan G, Karis M, Noordin Y,
author_sort	Mohd Azizan G,
title	Spinal anaesthesia with bupivacaine and intrathecal morphine versus combined spinal-epidural anaesthesia using bupivacaine and epidural infusion of bupivacaine plus fentanyl for postoperative analgesia after hip and knee arthroplasty.
title_short	Spinal anaesthesia with bupivacaine and intrathecal morphine versus combined spinal-epidural anaesthesia using bupivacaine and epidural infusion of bupivacaine plus fentanyl for postoperative analgesia after hip and knee arthroplasty.
title_full	Spinal anaesthesia with bupivacaine and intrathecal morphine versus combined spinal-epidural anaesthesia using bupivacaine and epidural infusion of bupivacaine plus fentanyl for postoperative analgesia after hip and knee arthroplasty.
title_fullStr	Spinal anaesthesia with bupivacaine and intrathecal morphine versus combined spinal-epidural anaesthesia using bupivacaine and epidural infusion of bupivacaine plus fentanyl for postoperative analgesia after hip and knee arthroplasty.
title_full_unstemmed	Spinal anaesthesia with bupivacaine and intrathecal morphine versus combined spinal-epidural anaesthesia using bupivacaine and epidural infusion of bupivacaine plus fentanyl for postoperative analgesia after hip and knee arthroplasty.
title_sort	spinal anaesthesia with bupivacaine and intrathecal morphine versus combined spinal-epidural anaesthesia using bupivacaine and epidural infusion of bupivacaine plus fentanyl for postoperative analgesia after hip and knee arthroplasty.
publisher	Department of Surgery, UKM Medical Centre
publishDate	2013
url	http://journalarticle.ukm.my/6724/ http://journalarticle.ukm.my/6724/ http://journalarticle.ukm.my/6724/1/09-MS1117_%2846-53%29.pdf
first_indexed	2023-09-18T19:47:43Z
last_indexed	2023-09-18T19:47:43Z
_version_	1777406012033073152

Spinal anaesthesia with bupivacaine and intrathecal morphine versus combined spinal-epidural anaesthesia using bupivacaine and epidural infusion of bupivacaine plus fentanyl for postoperative analgesia after hip and knee arthroplasty.

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