Extra-gonadal germ cell tumour – what about the testis!

Extra-gonadal germ cell tumour – what about the testis!

Extra-gonadal germ cell tumours (EGGCT) are rare. Therefore further investigations of the testis is aimed at sourcing a possible primary origin of gonadal tumour. Over the years, various case series on EGGCT have been reported questioning its true nature as in a majority of them, a primary source is...

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Main Authors: Johann FK, Praveen S, Christopher CKH, Goh EH, Razman J, Zulkifli MZ
Format: Article
Language:English
Published: Department of Surgery, UKM Medical Centre 2011
Online Access:http://journalarticle.ukm.my/807/
http://journalarticle.ukm.my/807/
http://journalarticle.ukm.my/807/1/34-36.pdf
id ukm-807
recordtype eprints
spelling ukm-8072016-12-14T06:28:14Z http://journalarticle.ukm.my/807/ Extra-gonadal germ cell tumour – what about the testis! Johann FK, Praveen S, Christopher CKH, Goh EH, Razman J, Zulkifli MZ, Extra-gonadal germ cell tumours (EGGCT) are rare. Therefore further investigations of the testis is aimed at sourcing a possible primary origin of gonadal tumour. Over the years, various case series on EGGCT have been reported questioning its true nature as in a majority of them, a primary source is found in the testis, thus representing a metastatic gonadal tumour. The testis pathology could be either a true germ cell foci, an intra-tubular epithelial neoplasia or an area of fibrosis, indicating a „burnt out tumour‟. We report a 39-year-old male who underwent laparotomy and excision of a retroperitoneal tumour. Histopathological examination revealed retroperitoneal lymph node of mixed germ cell tumour origin. Clinical and ultrasound examination of bilateral testis was normal. The patient refused orchidectomy or a testicular biopsy. He underwent four cycles of bleomycin, cisplatin, and etoposide with no evidence of tumour recurrence on follow up and remains disease free after 12 months of diagnosis. A literature review of EGGCT, its relation and factors relating with future testicular tumour is presented. Department of Surgery, UKM Medical Centre 2011-04-04 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/807/1/34-36.pdf Johann FK, and Praveen S, and Christopher CKH, and Goh EH, and Razman J, and Zulkifli MZ, (2011) Extra-gonadal germ cell tumour – what about the testis! Journal of Surgical Academia, 1 (1). pp. 34-36. ISSN 2231-7481 http://jsurgacad.com/
repository_type Digital Repository
institution_category Local University
institution Universiti Kebangasaan Malaysia
building UKM Institutional Repository
collection Online Access
language English
description Extra-gonadal germ cell tumours (EGGCT) are rare. Therefore further investigations of the testis is aimed at sourcing a possible primary origin of gonadal tumour. Over the years, various case series on EGGCT have been reported questioning its true nature as in a majority of them, a primary source is found in the testis, thus representing a metastatic gonadal tumour. The testis pathology could be either a true germ cell foci, an intra-tubular epithelial neoplasia or an area of fibrosis, indicating a „burnt out tumour‟. We report a 39-year-old male who underwent laparotomy and excision of a retroperitoneal tumour. Histopathological examination revealed retroperitoneal lymph node of mixed germ cell tumour origin. Clinical and ultrasound examination of bilateral testis was normal. The patient refused orchidectomy or a testicular biopsy. He underwent four cycles of bleomycin, cisplatin, and etoposide with no evidence of tumour recurrence on follow up and remains disease free after 12 months of diagnosis. A literature review of EGGCT, its relation and factors relating with future testicular tumour is presented.
format Article
author Johann FK,
Praveen S,
Christopher CKH,
Goh EH,
Razman J,
Zulkifli MZ,
spellingShingle Johann FK,
Praveen S,
Christopher CKH,
Goh EH,
Razman J,
Zulkifli MZ,
Extra-gonadal germ cell tumour – what about the testis!
author_facet Johann FK,
Praveen S,
Christopher CKH,
Goh EH,
Razman J,
Zulkifli MZ,
author_sort Johann FK,
title Extra-gonadal germ cell tumour – what about the testis!
title_short Extra-gonadal germ cell tumour – what about the testis!
title_full Extra-gonadal germ cell tumour – what about the testis!
title_fullStr Extra-gonadal germ cell tumour – what about the testis!
title_full_unstemmed Extra-gonadal germ cell tumour – what about the testis!
title_sort extra-gonadal germ cell tumour – what about the testis!
publisher Department of Surgery, UKM Medical Centre
publishDate 2011
url http://journalarticle.ukm.my/807/
http://journalarticle.ukm.my/807/
http://journalarticle.ukm.my/807/1/34-36.pdf
first_indexed 2023-09-18T19:31:49Z
last_indexed 2023-09-18T19:31:49Z
_version_ 1777405011720929280

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