The history of RNAi and microRNA discovery

MicroRNAs belong to one of the classes of non-coding RNAs. Non-coding RNAs are functional RNAs that do not translate into protein. They comprise: transfer RNA (tRNA); ribosomal RNA (rRNA); small nucleolar RNA (snoRNA); microRNA (miRNA); small interfering RNA (siRNAs); small nuclear RNA (snRNA); piwi...

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Main Author:	Tan, GC
Format:	Article
Language:	English
Published:	Penerbit UKM 2014
Subjects:	RZ Other systems of medicine
Online Access:	http://journalarticle.ukm.my/8256/ http://journalarticle.ukm.my/8256/ http://journalarticle.ukm.my/8256/1/01-Editorial_%2890-91%29.pdf

id	ukm-8256
recordtype	eprints
spelling	ukm-82562016-12-14T06:46:42Z http://journalarticle.ukm.my/8256/ The history of RNAi and microRNA discovery Tan, GC RZ Other systems of medicine MicroRNAs belong to one of the classes of non-coding RNAs. Non-coding RNAs are functional RNAs that do not translate into protein. They comprise: transfer RNA (tRNA); ribosomal RNA (rRNA); small nucleolar RNA (snoRNA); microRNA (miRNA); small interfering RNA (siRNAs); small nuclear RNA (snRNA); piwi-interacting RNA (piRNA), and long ncRNA. To date, there are approximately 1881 pre-miRNAs and 2588 mature human miRNAs have been identified (miRBase, June 2014). MicroRNAs are about 19-25 nucleotides in length and are now known to have important post-transcriptional roles in almost every cellular process in eukaryotes. These processes include the regulation of developmental timing and signalling pathways, apoptosis, metabolism, myogenesis and cardiogenesis, brain development, and human pathologies like viral diseases, genetic disorders and cancer (Shi et al. 2008). Penerbit UKM 2014-06-01 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/8256/1/01-Editorial_%2890-91%29.pdf Tan, GC (2014) The history of RNAi and microRNA discovery. Medicine & Health, 9 (2). pp. 90-91. ISSN 1823-2140 http://www.medicineandhealthukm.com
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
topic	RZ Other systems of medicine
spellingShingle	RZ Other systems of medicine Tan, GC The history of RNAi and microRNA discovery
description	MicroRNAs belong to one of the classes of non-coding RNAs. Non-coding RNAs are functional RNAs that do not translate into protein. They comprise: transfer RNA (tRNA); ribosomal RNA (rRNA); small nucleolar RNA (snoRNA); microRNA (miRNA); small interfering RNA (siRNAs); small nuclear RNA (snRNA); piwi-interacting RNA (piRNA), and long ncRNA. To date, there are approximately 1881 pre-miRNAs and 2588 mature human miRNAs have been identified (miRBase, June 2014). MicroRNAs are about 19-25 nucleotides in length and are now known to have important post-transcriptional roles in almost every cellular process in eukaryotes. These processes include the regulation of developmental timing and signalling pathways, apoptosis, metabolism, myogenesis and cardiogenesis, brain development, and human pathologies like viral diseases, genetic disorders and cancer (Shi et al. 2008).
format	Article
author	Tan, GC
author_facet	Tan, GC
author_sort	Tan, GC
title	The history of RNAi and microRNA discovery
title_short	The history of RNAi and microRNA discovery
title_full	The history of RNAi and microRNA discovery
title_fullStr	The history of RNAi and microRNA discovery
title_full_unstemmed	The history of RNAi and microRNA discovery
title_sort	history of rnai and microrna discovery
publisher	Penerbit UKM
publishDate	2014
url	http://journalarticle.ukm.my/8256/ http://journalarticle.ukm.my/8256/ http://journalarticle.ukm.my/8256/1/01-Editorial_%2890-91%29.pdf
first_indexed	2023-09-18T19:51:56Z
last_indexed	2023-09-18T19:51:56Z
_version_	1777406277166563328

The history of RNAi and microRNA discovery

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