Modeling of the dissolution kinetics of arbutus wild berries-based tablets as evaluated by electric conductivity

Lyophilized powder (LP) from Algerian arbutus wild berries (Arbutus unedo L.) was obtained. This present paper reports about the dissolution (releasing) properties of LP-based tablets, evaluated through the electric conductivity (EC) of distilled water which is employed as surrounding medium, at thr...

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Main Authors: Abbas-Aksil, Tounsia, Benamara, Salem
Format: Article
Language:English
Published: Universiti Kebangsaan Malaysia 2015
Online Access:http://journalarticle.ukm.my/8317/
http://journalarticle.ukm.my/8317/
http://journalarticle.ukm.my/8317/1/20_Tounsia_Abbas.pdf
id ukm-8317
recordtype eprints
spelling ukm-83172016-12-14T06:46:54Z http://journalarticle.ukm.my/8317/ Modeling of the dissolution kinetics of arbutus wild berries-based tablets as evaluated by electric conductivity Abbas-Aksil, Tounsia Benamara, Salem Lyophilized powder (LP) from Algerian arbutus wild berries (Arbutus unedo L.) was obtained. This present paper reports about the dissolution (releasing) properties of LP-based tablets, evaluated through the electric conductivity (EC) of distilled water which is employed as surrounding medium, at three different temperatures (291, 298 and 309 K). In addition to this, secondary physicochemical characteristics such as elementary analysis, color and compressibility were evaluated. Regarding the modeling of ionic transfer, among the three tested models, namely Peleg, Singh et al. and Singh and Kulshestha, the latter seems to be the most appropriate (R2 = 0.99), particularly in the case of compacted tablets under 2000 Pa. The temperature dependence of the dissolution process was also studied applying Arrhenius equation (R2>0.8) which allowed to deduce the activation energy, ranging from 18.7 to 21.4 kJ.mol-1 according to the model and compression force employed. Universiti Kebangsaan Malaysia 2015-02 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/8317/1/20_Tounsia_Abbas.pdf Abbas-Aksil, Tounsia and Benamara, Salem (2015) Modeling of the dissolution kinetics of arbutus wild berries-based tablets as evaluated by electric conductivity. Sains Malaysiana, 44 (2). pp. 301-308. ISSN 0126-6039 http://www.ukm.my/jsm/
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institution Universiti Kebangasaan Malaysia
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language English
description Lyophilized powder (LP) from Algerian arbutus wild berries (Arbutus unedo L.) was obtained. This present paper reports about the dissolution (releasing) properties of LP-based tablets, evaluated through the electric conductivity (EC) of distilled water which is employed as surrounding medium, at three different temperatures (291, 298 and 309 K). In addition to this, secondary physicochemical characteristics such as elementary analysis, color and compressibility were evaluated. Regarding the modeling of ionic transfer, among the three tested models, namely Peleg, Singh et al. and Singh and Kulshestha, the latter seems to be the most appropriate (R2 = 0.99), particularly in the case of compacted tablets under 2000 Pa. The temperature dependence of the dissolution process was also studied applying Arrhenius equation (R2>0.8) which allowed to deduce the activation energy, ranging from 18.7 to 21.4 kJ.mol-1 according to the model and compression force employed.
format Article
author Abbas-Aksil, Tounsia
Benamara, Salem
spellingShingle Abbas-Aksil, Tounsia
Benamara, Salem
Modeling of the dissolution kinetics of arbutus wild berries-based tablets as evaluated by electric conductivity
author_facet Abbas-Aksil, Tounsia
Benamara, Salem
author_sort Abbas-Aksil, Tounsia
title Modeling of the dissolution kinetics of arbutus wild berries-based tablets as evaluated by electric conductivity
title_short Modeling of the dissolution kinetics of arbutus wild berries-based tablets as evaluated by electric conductivity
title_full Modeling of the dissolution kinetics of arbutus wild berries-based tablets as evaluated by electric conductivity
title_fullStr Modeling of the dissolution kinetics of arbutus wild berries-based tablets as evaluated by electric conductivity
title_full_unstemmed Modeling of the dissolution kinetics of arbutus wild berries-based tablets as evaluated by electric conductivity
title_sort modeling of the dissolution kinetics of arbutus wild berries-based tablets as evaluated by electric conductivity
publisher Universiti Kebangsaan Malaysia
publishDate 2015
url http://journalarticle.ukm.my/8317/
http://journalarticle.ukm.my/8317/
http://journalarticle.ukm.my/8317/1/20_Tounsia_Abbas.pdf
first_indexed 2023-09-18T19:52:04Z
last_indexed 2023-09-18T19:52:04Z
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