Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines
Three novel ruthenium(II) complexes of the general formula [Ru(II)(bpy)2L]2+ were synthesized, where L = 1,10-phenanthroline derivatives of position 2 imidazole having 3,4-didecyloxy-phenyl (ddip), 3,4-ditetradecyloxy-phenyl (dtip) and 3,4-dihexadecyloxy-phenyl (dhip). All complexes were characteriz...
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Universiti Kebangsaan Malaysia
2015
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| Online Access: | http://journalarticle.ukm.my/8641/ http://journalarticle.ukm.my/8641/ http://journalarticle.ukm.my/8641/1/18_T.T.C__Ting.pdf |
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ukm-86412016-12-14T06:47:46Z http://journalarticle.ukm.my/8641/ Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines Ting, T.T.C. Crouse, K.A. Ahmad, H. Three novel ruthenium(II) complexes of the general formula [Ru(II)(bpy)2L]2+ were synthesized, where L = 1,10-phenanthroline derivatives of position 2 imidazole having 3,4-didecyloxy-phenyl (ddip), 3,4-ditetradecyloxy-phenyl (dtip) and 3,4-dihexadecyloxy-phenyl (dhip). All complexes were characterized by elemental analysis, 1H-NMR and ESI-MS. Their photophysical properties have also been studied by UV-visible spectroscopy and fluorescence spectroscopy. The complexes exhibit Ru(II) metal centered emission at approximately 610 nm in acetonitrile solution at room temperature. DNA binding studies were carried out by UV-visible titration, luminescence titration and viscosity studies. The results indicated that [Ru(bpy)2(ddip)]2+ binds to CT-DNA by partial intercalation mode, while [Ru(bpy)2(dtip)]2+ and [Ru(bpy)2(dhip)]2+ bind intercalatively via extended ligands. Universiti Kebangsaan Malaysia 2015-04 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/8641/1/18_T.T.C__Ting.pdf Ting, T.T.C. and Crouse, K.A. and Ahmad, H. (2015) Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines. Sains Malaysiana, 44 (4). pp. 619-628. ISSN 0126-6039 http://www.ukm.my/jsm/malay_journals/jilid44bil4_2015/KandunganJilid44Bil4_2015.html |
| repository_type |
Digital Repository |
| institution_category |
Local University |
| institution |
Universiti Kebangasaan Malaysia |
| building |
UKM Institutional Repository |
| collection |
Online Access |
| language |
English |
| description |
Three novel ruthenium(II) complexes of the general formula [Ru(II)(bpy)2L]2+ were synthesized, where L = 1,10-phenanthroline derivatives of position 2 imidazole having 3,4-didecyloxy-phenyl (ddip), 3,4-ditetradecyloxy-phenyl (dtip) and 3,4-dihexadecyloxy-phenyl (dhip). All complexes were characterized by elemental analysis, 1H-NMR and ESI-MS. Their photophysical properties have also been studied by UV-visible spectroscopy and fluorescence spectroscopy. The complexes exhibit Ru(II) metal centered emission at approximately 610 nm in acetonitrile solution at room temperature. DNA binding studies were carried out by UV-visible titration, luminescence titration and viscosity studies. The results indicated that [Ru(bpy)2(ddip)]2+ binds to CT-DNA by partial intercalation mode, while [Ru(bpy)2(dtip)]2+ and [Ru(bpy)2(dhip)]2+ bind intercalatively via extended ligands. |
| format |
Article |
| author |
Ting, T.T.C. Crouse, K.A. Ahmad, H. |
| spellingShingle |
Ting, T.T.C. Crouse, K.A. Ahmad, H. Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines |
| author_facet |
Ting, T.T.C. Crouse, K.A. Ahmad, H. |
| author_sort |
Ting, T.T.C. |
| title |
Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines |
| title_short |
Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines |
| title_full |
Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines |
| title_fullStr |
Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines |
| title_full_unstemmed |
Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines |
| title_sort |
synthesis, characterization and dna binding studies of [ruthenium(ii)(bpy)2l]2+ where l are derivatives of imidazo[4,5-f]-1,10-phenanthrolines |
| publisher |
Universiti Kebangsaan Malaysia |
| publishDate |
2015 |
| url |
http://journalarticle.ukm.my/8641/ http://journalarticle.ukm.my/8641/ http://journalarticle.ukm.my/8641/1/18_T.T.C__Ting.pdf |
| first_indexed |
2023-09-18T19:52:52Z |
| last_indexed |
2023-09-18T19:52:52Z |
| _version_ |
1777406336137428992 |