Evaluation of organ at risk (OAR) doses based on 2D treatment planning in intracavitary brachytherapy of cervical cancer

Conventional two-dimensional (2D) treatment planning of intracavitary brachytherapy is still a common practice at the radiotherapy center. The purpose of this study was to evaluate the organ at risk (OAR) doses estimated based on International Commission on Radiation Units and Measurements (ICRU) re...

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Main Authors:	Reduan Abdullah, Nur Aqilah Abdul Sani, Chen, Suk Chiang, Mazurawati Mohamed, Nik Ruzman Nik Idris, Ahmad Lutfi Yusoff, Bhavaraju VMK
Format:	Article
Language:	English
Published:	Universiti Kebangsaan Malaysia 2015
Online Access:	http://journalarticle.ukm.my/9044/ http://journalarticle.ukm.my/9044/ http://journalarticle.ukm.my/9044/1/10_Reduan_Abdullah.pdf

id	ukm-9044
recordtype	eprints
spelling	ukm-90442016-12-14T06:48:48Z http://journalarticle.ukm.my/9044/ Evaluation of organ at risk (OAR) doses based on 2D treatment planning in intracavitary brachytherapy of cervical cancer Reduan Abdullah, Nur Aqilah Abdul Sani, Chen, Suk Chiang Mazurawati Mohamed, Nik Ruzman Nik Idris, Ahmad Lutfi Yusoff, Bhavaraju VMK, Conventional two-dimensional (2D) treatment planning of intracavitary brachytherapy is still a common practice at the radiotherapy center. The purpose of this study was to evaluate the organ at risk (OAR) doses estimated based on International Commission on Radiation Units and Measurements (ICRU) reference-point in patients with cervical cancer treated with high-dose-rate (HDR) intracavitary brachytherapy (ICBT). Between January 2010 and April 2014, 21 cervical cancer patients were treated with 42 fractions of brachytherapy using tandem and ovoids and underwent post-implant two-dimensional (2D) radiograph scans. HDR brachytherapy was delivered to a dose of 18 Gy in two fractions. Using the Oncentra brachytherapy treatment planning system (BTPS) software version 4.1 (Nucletron, Netherlands), the bladder and rectum points were retrospectively reconstructed based on 42 orthogonal radiographs datasets. The ICRU bladder and rectum point doses were recorded. As for results, the mean percentage dose of rectum and bladder for selected patients treated with intracavitary brachytherapy treatment (ICBT) were 47.27 and 75.59%, respectively. Combinations of ovoid’s size, length of tandem and anatomy variation between each patient were factors that affected the dose to the OAR. Therefore, the ICRU reference points can still be used with the 2D brachytherapy treatment planning in evaluating the OAR doses. Universiti Kebangsaan Malaysia 2015-08 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/9044/1/10_Reduan_Abdullah.pdf Reduan Abdullah, and Nur Aqilah Abdul Sani, and Chen, Suk Chiang and Mazurawati Mohamed, and Nik Ruzman Nik Idris, and Ahmad Lutfi Yusoff, and Bhavaraju VMK, (2015) Evaluation of organ at risk (OAR) doses based on 2D treatment planning in intracavitary brachytherapy of cervical cancer. Sains Malaysiana, 44 (4). pp. 1145-1151. ISSN 0126-6039 http://www.ukm.my/jsm/english_journals/vol44num8_2015/contentsVol44num8_2015.html
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	Conventional two-dimensional (2D) treatment planning of intracavitary brachytherapy is still a common practice at the radiotherapy center. The purpose of this study was to evaluate the organ at risk (OAR) doses estimated based on International Commission on Radiation Units and Measurements (ICRU) reference-point in patients with cervical cancer treated with high-dose-rate (HDR) intracavitary brachytherapy (ICBT). Between January 2010 and April 2014, 21 cervical cancer patients were treated with 42 fractions of brachytherapy using tandem and ovoids and underwent post-implant two-dimensional (2D) radiograph scans. HDR brachytherapy was delivered to a dose of 18 Gy in two fractions. Using the Oncentra brachytherapy treatment planning system (BTPS) software version 4.1 (Nucletron, Netherlands), the bladder and rectum points were retrospectively reconstructed based on 42 orthogonal radiographs datasets. The ICRU bladder and rectum point doses were recorded. As for results, the mean percentage dose of rectum and bladder for selected patients treated with intracavitary brachytherapy treatment (ICBT) were 47.27 and 75.59%, respectively. Combinations of ovoid’s size, length of tandem and anatomy variation between each patient were factors that affected the dose to the OAR. Therefore, the ICRU reference points can still be used with the 2D brachytherapy treatment planning in evaluating the OAR doses.
format	Article
author	Reduan Abdullah, Nur Aqilah Abdul Sani, Chen, Suk Chiang Mazurawati Mohamed, Nik Ruzman Nik Idris, Ahmad Lutfi Yusoff, Bhavaraju VMK,
spellingShingle	Reduan Abdullah, Nur Aqilah Abdul Sani, Chen, Suk Chiang Mazurawati Mohamed, Nik Ruzman Nik Idris, Ahmad Lutfi Yusoff, Bhavaraju VMK, Evaluation of organ at risk (OAR) doses based on 2D treatment planning in intracavitary brachytherapy of cervical cancer
author_facet	Reduan Abdullah, Nur Aqilah Abdul Sani, Chen, Suk Chiang Mazurawati Mohamed, Nik Ruzman Nik Idris, Ahmad Lutfi Yusoff, Bhavaraju VMK,
author_sort	Reduan Abdullah,
title	Evaluation of organ at risk (OAR) doses based on 2D treatment planning in intracavitary brachytherapy of cervical cancer
title_short	Evaluation of organ at risk (OAR) doses based on 2D treatment planning in intracavitary brachytherapy of cervical cancer
title_full	Evaluation of organ at risk (OAR) doses based on 2D treatment planning in intracavitary brachytherapy of cervical cancer
title_fullStr	Evaluation of organ at risk (OAR) doses based on 2D treatment planning in intracavitary brachytherapy of cervical cancer
title_full_unstemmed	Evaluation of organ at risk (OAR) doses based on 2D treatment planning in intracavitary brachytherapy of cervical cancer
title_sort	evaluation of organ at risk (oar) doses based on 2d treatment planning in intracavitary brachytherapy of cervical cancer
publisher	Universiti Kebangsaan Malaysia
publishDate	2015
url	http://journalarticle.ukm.my/9044/ http://journalarticle.ukm.my/9044/ http://journalarticle.ukm.my/9044/1/10_Reduan_Abdullah.pdf
first_indexed	2023-09-18T19:53:50Z
last_indexed	2023-09-18T19:53:50Z
_version_	1777406396508143616

Evaluation of organ at risk (OAR) doses based on 2D treatment planning in intracavitary brachytherapy of cervical cancer

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