Antihyperglycemic Activity of Oil Palm Elaeis guineensis Fruit Extract on Streptozotocin-induced Diabetic Rats

Hypoglycaemic and antihyperglycemic activity of oil palm Elaeis guineensis fruit extract on normal and Streptozotocin-induced diabetic rats was studied. The oil palm fruit extract (OPF) were administered orally at different concentrations (100, 200 and 500 mg kg-1 b.w.) in fasting and post-prandial...

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Main Authors:	Faez Sharif, Muhajir Hamid, Amin Ismail, Zainah Adam
Format:	Article
Language:	English
Published:	Penerbit UKM 2015
Subjects:	RA Public aspects of medicine
Online Access:	http://journalarticle.ukm.my/9401/ http://journalarticle.ukm.my/9401/ http://journalarticle.ukm.my/9401/1/10876-29609-1-SM.pdf

id	ukm-9401
recordtype	eprints
spelling	ukm-94012016-12-14T06:49:49Z http://journalarticle.ukm.my/9401/ Antihyperglycemic Activity of Oil Palm Elaeis guineensis Fruit Extract on Streptozotocin-induced Diabetic Rats Faez Sharif, Muhajir Hamid, Amin Ismail, Zainah Adam, RA Public aspects of medicine Hypoglycaemic and antihyperglycemic activity of oil palm Elaeis guineensis fruit extract on normal and Streptozotocin-induced diabetic rats was studied. The oil palm fruit extract (OPF) were administered orally at different concentrations (100, 200 and 500 mg kg-1 b.w.) in fasting and post-prandial rats. Hypoglycaemia was not observed in the group of normal rats treated with OPF. In fasting rats, OPF (500 mg kg-1 b.w.) has caused the blood glucose level (BGL) to reduce significantly. For post-prandial diabetic rats, the antihyperglycemic activity was observed after OPF treatment at concentrations 200 and 500 mg kg-1. Chronic OPF treatments (for 28 days) had increased the diabetic rat’s body weight and reduced BGL as well as improved plasma insulin secretion. The result of this study suggests E. guineensis palm fruit extract show evidence of antihyperglycemic properties from the reduction of the BGL in diabetic rats. Penerbit UKM 2015 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/9401/1/10876-29609-1-SM.pdf Faez Sharif, and Muhajir Hamid, and Amin Ismail, and Zainah Adam, (2015) Antihyperglycemic Activity of Oil Palm Elaeis guineensis Fruit Extract on Streptozotocin-induced Diabetic Rats. Jurnal Sains Kesihatan Malaysia, 13 (2). pp. 37-43. ISSN 1675-8161 http://ejournal.ukm.my/jskm/article/view/10876
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
topic	RA Public aspects of medicine
spellingShingle	RA Public aspects of medicine Faez Sharif, Muhajir Hamid, Amin Ismail, Zainah Adam, Antihyperglycemic Activity of Oil Palm Elaeis guineensis Fruit Extract on Streptozotocin-induced Diabetic Rats
description	Hypoglycaemic and antihyperglycemic activity of oil palm Elaeis guineensis fruit extract on normal and Streptozotocin-induced diabetic rats was studied. The oil palm fruit extract (OPF) were administered orally at different concentrations (100, 200 and 500 mg kg-1 b.w.) in fasting and post-prandial rats. Hypoglycaemia was not observed in the group of normal rats treated with OPF. In fasting rats, OPF (500 mg kg-1 b.w.) has caused the blood glucose level (BGL) to reduce significantly. For post-prandial diabetic rats, the antihyperglycemic activity was observed after OPF treatment at concentrations 200 and 500 mg kg-1. Chronic OPF treatments (for 28 days) had increased the diabetic rat’s body weight and reduced BGL as well as improved plasma insulin secretion. The result of this study suggests E. guineensis palm fruit extract show evidence of antihyperglycemic properties from the reduction of the BGL in diabetic rats.
format	Article
author	Faez Sharif, Muhajir Hamid, Amin Ismail, Zainah Adam,
author_facet	Faez Sharif, Muhajir Hamid, Amin Ismail, Zainah Adam,
author_sort	Faez Sharif,
title	Antihyperglycemic Activity of Oil Palm Elaeis guineensis Fruit Extract on Streptozotocin-induced Diabetic Rats
title_short	Antihyperglycemic Activity of Oil Palm Elaeis guineensis Fruit Extract on Streptozotocin-induced Diabetic Rats
title_full	Antihyperglycemic Activity of Oil Palm Elaeis guineensis Fruit Extract on Streptozotocin-induced Diabetic Rats
title_fullStr	Antihyperglycemic Activity of Oil Palm Elaeis guineensis Fruit Extract on Streptozotocin-induced Diabetic Rats
title_full_unstemmed	Antihyperglycemic Activity of Oil Palm Elaeis guineensis Fruit Extract on Streptozotocin-induced Diabetic Rats
title_sort	antihyperglycemic activity of oil palm elaeis guineensis fruit extract on streptozotocin-induced diabetic rats
publisher	Penerbit UKM
publishDate	2015
url	http://journalarticle.ukm.my/9401/ http://journalarticle.ukm.my/9401/ http://journalarticle.ukm.my/9401/1/10876-29609-1-SM.pdf
first_indexed	2023-09-18T19:54:45Z
last_indexed	2023-09-18T19:54:45Z
_version_	1777406454052945920

Antihyperglycemic Activity of Oil Palm Elaeis guineensis Fruit Extract on Streptozotocin-induced Diabetic Rats

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