The Oestrogenis and Cytotoxic Effects of the Extracts of Labisia pumila var. alata and Labisia pumila var. pumila In Vitro

Aqueous, acid hydrolysed and ethanolic extracts of the roots and leaves of Labisia pumila var. alata and Labisia pumila var. alata and Labisia pumila var. pumila were investigated for their oestrogenic and cytotoxic effects using Ishikawa cell line by performing an in vitro Ishikawa alkaline phospha...

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Main Authors:	Jamia A.Jamal, Houghton P.J, Milligan S.R, Ibrahim Jantan
Format:	Article
Language:	English
Published:	2003
Online Access:	http://journalarticle.ukm.my/950/ http://journalarticle.ukm.my/950/1/jurnal6.pdf

id	ukm-950
recordtype	eprints
spelling	ukm-9502016-12-14T06:28:23Z http://journalarticle.ukm.my/950/ The Oestrogenis and Cytotoxic Effects of the Extracts of Labisia pumila var. alata and Labisia pumila var. pumila In Vitro Jamia A.Jamal, Houghton P.J, Milligan S.R, Ibrahim Jantan, Aqueous, acid hydrolysed and ethanolic extracts of the roots and leaves of Labisia pumila var. alata and Labisia pumila var. alata and Labisia pumila var. pumila were investigated for their oestrogenic and cytotoxic effects using Ishikawa cell line by performing an in vitro Ishikawa alkaline phosphatase assay and an in vitro protein assay, respectively. Among them, only the ethanol extract of the root of L. pumila var. alata exhibited a weak oestrogenic activity at 10-50 mg/ml. The samples that exhibited significant cytotoxic effect were the ethanol extract of the roots of L. pumila var. alata (IC50 433 mg/ml), and the aqueous extracts of the roots of L. pumila var. alata (IC50 433 mg/ml) and the leaves of L. pumila var. pumila (IC50 458 mg/ml). 2003-07 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/950/1/jurnal6.pdf Jamia A.Jamal, and Houghton P.J, and Milligan S.R, and Ibrahim Jantan, (2003) The Oestrogenis and Cytotoxic Effects of the Extracts of Labisia pumila var. alata and Labisia pumila var. pumila In Vitro. pp. 53-60. ISSN 1675-8161
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	Aqueous, acid hydrolysed and ethanolic extracts of the roots and leaves of Labisia pumila var. alata and Labisia pumila var. alata and Labisia pumila var. pumila were investigated for their oestrogenic and cytotoxic effects using Ishikawa cell line by performing an in vitro Ishikawa alkaline phosphatase assay and an in vitro protein assay, respectively. Among them, only the ethanol extract of the root of L. pumila var. alata exhibited a weak oestrogenic activity at 10-50 mg/ml. The samples that exhibited significant cytotoxic effect were the ethanol extract of the roots of L. pumila var. alata (IC50 433 mg/ml), and the aqueous extracts of the roots of L. pumila var. alata (IC50 433 mg/ml) and the leaves of L. pumila var. pumila (IC50 458 mg/ml).
format	Article
author	Jamia A.Jamal, Houghton P.J, Milligan S.R, Ibrahim Jantan,
spellingShingle	Jamia A.Jamal, Houghton P.J, Milligan S.R, Ibrahim Jantan, The Oestrogenis and Cytotoxic Effects of the Extracts of Labisia pumila var. alata and Labisia pumila var. pumila In Vitro
author_facet	Jamia A.Jamal, Houghton P.J, Milligan S.R, Ibrahim Jantan,
author_sort	Jamia A.Jamal,
title	The Oestrogenis and Cytotoxic Effects of the Extracts of Labisia pumila var. alata and Labisia pumila var. pumila In Vitro
title_short	The Oestrogenis and Cytotoxic Effects of the Extracts of Labisia pumila var. alata and Labisia pumila var. pumila In Vitro
title_full	The Oestrogenis and Cytotoxic Effects of the Extracts of Labisia pumila var. alata and Labisia pumila var. pumila In Vitro
title_fullStr	The Oestrogenis and Cytotoxic Effects of the Extracts of Labisia pumila var. alata and Labisia pumila var. pumila In Vitro
title_full_unstemmed	The Oestrogenis and Cytotoxic Effects of the Extracts of Labisia pumila var. alata and Labisia pumila var. pumila In Vitro
title_sort	oestrogenis and cytotoxic effects of the extracts of labisia pumila var. alata and labisia pumila var. pumila in vitro
publishDate	2003
url	http://journalarticle.ukm.my/950/ http://journalarticle.ukm.my/950/1/jurnal6.pdf
first_indexed	2023-09-18T19:31:59Z
last_indexed	2023-09-18T19:31:59Z
_version_	1777405021957128192

The Oestrogenis and Cytotoxic Effects of the Extracts of Labisia pumila var. alata and Labisia pumila var. pumila In Vitro

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