Inhibitory effects of the extracts of Plantago major Linn. on the Number and Size of Calcium Oxalate Crystals in vitro

This study was carried out to determine the inhibitory effects of the various extracts of Plantago major on calcium oxalate crystals in vitro. The petroleum ether, n-butanol, ethanol, methanol and aqueous extracts of P. major were each used at a concentration of 10 mg/ml and dimethylsulfoxide (DMSO)...

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Main Authors:	Sharifa Abdul Aziz, Suhana Md Saad, Khairol Osman, Khartini Abd Wahab, Mohd Azman Abu Bakar
Format:	Article
Language:	English
Published:	penerbit ukm 2004
Online Access:	http://journalarticle.ukm.my/955/ http://journalarticle.ukm.my/955/ http://journalarticle.ukm.my/955/1/jurnal11.pdf

id	ukm-955
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spelling	ukm-9552016-12-14T06:28:24Z http://journalarticle.ukm.my/955/ Inhibitory effects of the extracts of Plantago major Linn. on the Number and Size of Calcium Oxalate Crystals in vitro Sharifa Abdul Aziz, Suhana Md Saad, Khairol Osman, Khartini Abd Wahab, Mohd Azman Abu Bakar, This study was carried out to determine the inhibitory effects of the various extracts of Plantago major on calcium oxalate crystals in vitro. The petroleum ether, n-butanol, ethanol, methanol and aqueous extracts of P. major were each used at a concentration of 10 mg/ml and dimethylsulfoxide (DMSO) was used as a control. Modified Schneider slide gel method was used and the number and size of calcium oxalate crystals (both dihydrate and monohydrate types) were counted every 24 hrs by using the Image Analyser system. There was a significant reduction in the size of the calcium oxalate dihydrate crystals by all of the extracts except for petroleum ether extract compared to the control (p < 0.05). The significant reduction in the size of the monohydrate crystals was only observed in the n-butanol and water extracts (p < 0.05). The size of monohydrate crystal reduced significantly in n-butanol and water compared to zylorik (p < 0.05). The number of monohydrate crystals reduced significantly in the ethanol, n-butanol and water extracts compared to the control and in ethanol(also dyhydrate) and water extractcompared to zylorik (p < 0.05). These results indicated that most of the extracts of P. major could reduce the number and size of calcium oxalate crystals in vitro at 10 mg/ml after 24 hrs. penerbit ukm 2004 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/955/1/jurnal11.pdf Sharifa Abdul Aziz, and Suhana Md Saad, and Khairol Osman, and Khartini Abd Wahab, and Mohd Azman Abu Bakar, (2004) Inhibitory effects of the extracts of Plantago major Linn. on the Number and Size of Calcium Oxalate Crystals in vitro. Jurnal Sains Kesihatan Malaysia, 2 (1). pp. 89-92. ISSN 1675-8161 http://www.fskb.ukm.my/fskbold/jurnal
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	This study was carried out to determine the inhibitory effects of the various extracts of Plantago major on calcium oxalate crystals in vitro. The petroleum ether, n-butanol, ethanol, methanol and aqueous extracts of P. major were each used at a concentration of 10 mg/ml and dimethylsulfoxide (DMSO) was used as a control. Modified Schneider slide gel method was used and the number and size of calcium oxalate crystals (both dihydrate and monohydrate types) were counted every 24 hrs by using the Image Analyser system. There was a significant reduction in the size of the calcium oxalate dihydrate crystals by all of the extracts except for petroleum ether extract compared to the control (p < 0.05). The significant reduction in the size of the monohydrate crystals was only observed in the n-butanol and water extracts (p < 0.05). The size of monohydrate crystal reduced significantly in n-butanol and water compared to zylorik (p < 0.05). The number of monohydrate crystals reduced significantly in the ethanol, n-butanol and water extracts compared to the control and in ethanol(also dyhydrate) and water extractcompared to zylorik (p < 0.05). These results indicated that most of the extracts of P. major could reduce the number and size of calcium oxalate crystals in vitro at 10 mg/ml after 24 hrs.
format	Article
author	Sharifa Abdul Aziz, Suhana Md Saad, Khairol Osman, Khartini Abd Wahab, Mohd Azman Abu Bakar,
spellingShingle	Sharifa Abdul Aziz, Suhana Md Saad, Khairol Osman, Khartini Abd Wahab, Mohd Azman Abu Bakar, Inhibitory effects of the extracts of Plantago major Linn. on the Number and Size of Calcium Oxalate Crystals in vitro
author_facet	Sharifa Abdul Aziz, Suhana Md Saad, Khairol Osman, Khartini Abd Wahab, Mohd Azman Abu Bakar,
author_sort	Sharifa Abdul Aziz,
title	Inhibitory effects of the extracts of Plantago major Linn. on the Number and Size of Calcium Oxalate Crystals in vitro
title_short	Inhibitory effects of the extracts of Plantago major Linn. on the Number and Size of Calcium Oxalate Crystals in vitro
title_full	Inhibitory effects of the extracts of Plantago major Linn. on the Number and Size of Calcium Oxalate Crystals in vitro
title_fullStr	Inhibitory effects of the extracts of Plantago major Linn. on the Number and Size of Calcium Oxalate Crystals in vitro
title_full_unstemmed	Inhibitory effects of the extracts of Plantago major Linn. on the Number and Size of Calcium Oxalate Crystals in vitro
title_sort	inhibitory effects of the extracts of plantago major linn. on the number and size of calcium oxalate crystals in vitro
publisher	penerbit ukm
publishDate	2004
url	http://journalarticle.ukm.my/955/ http://journalarticle.ukm.my/955/ http://journalarticle.ukm.my/955/1/jurnal11.pdf
first_indexed	2023-09-18T19:31:59Z
last_indexed	2023-09-18T19:31:59Z
_version_	1777405022689034240

Inhibitory effects of the extracts of Plantago major Linn. on the Number and Size of Calcium Oxalate Crystals in vitro

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