Protective effects of Citrullus vulgaris on Irradiated Lymphocyte Sub-membrane

A study was conducted to determine the radioprotective effects of Citrullus vulgaris on the lymphocyte sub-membrane particularly the actin layer. A total of 30 adult male Sprague-Dawley rats were divided into three equal groups of positive control, negative control and treatment. The positive and ne...

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Main Authors:	Khairul Osman, Norashikin Md Saad, Ezlan Elias, Siti Fatimah Ibrahim, Jamaludin Mohamed, Proom Proomwichit
Format:	Article
Language:	English
Published:	penerbit ukm 2005
Online Access:	http://journalarticle.ukm.my/978/ http://journalarticle.ukm.my/978/ http://journalarticle.ukm.my/978/1/jurnal31.pdf

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recordtype	eprints
spelling	ukm-9782016-12-14T06:28:28Z http://journalarticle.ukm.my/978/ Protective effects of Citrullus vulgaris on Irradiated Lymphocyte Sub-membrane Khairul Osman, Norashikin Md Saad, Ezlan Elias, Siti Fatimah Ibrahim, Jamaludin Mohamed, Proom Proomwichit, A study was conducted to determine the radioprotective effects of Citrullus vulgaris on the lymphocyte sub-membrane particularly the actin layer. A total of 30 adult male Sprague-Dawley rats were divided into three equal groups of positive control, negative control and treatment. The positive and negative control groups were force fed with 40 ml/kg body weight of normal saline while the treatment group received 40 g/kg body weight of fresh juice of C. vulgaris daily. After a week the positive control and treatment groups were irradiated with 90 rad gamma radiation. Viable lymphocytes were determined using propidium iodine and acridine orange stain and observed under a fluorescent microscope. The percentage of viable lymphocytes of the treatment group(71.0%; p = 0.03) was significantly higher than the positive control group. The results showed that C. vulgaris possessed radioprotective effects because the lymphocyte actin was not damaged. The radioprotection effects could be due to the presence of antioxidants in C. vulgaris. penerbit ukm 2005 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/978/1/jurnal31.pdf Khairul Osman, and Norashikin Md Saad, and Ezlan Elias, and Siti Fatimah Ibrahim, and Jamaludin Mohamed, and Proom Proomwichit, (2005) Protective effects of Citrullus vulgaris on Irradiated Lymphocyte Sub-membrane. Jurnal Sains Kesihatan Malaysia, 3 (1). pp. 1-9. ISSN 1675-8161 http://www.fskb.ukm.my/fskbold/jurnal
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	A study was conducted to determine the radioprotective effects of Citrullus vulgaris on the lymphocyte sub-membrane particularly the actin layer. A total of 30 adult male Sprague-Dawley rats were divided into three equal groups of positive control, negative control and treatment. The positive and negative control groups were force fed with 40 ml/kg body weight of normal saline while the treatment group received 40 g/kg body weight of fresh juice of C. vulgaris daily. After a week the positive control and treatment groups were irradiated with 90 rad gamma radiation. Viable lymphocytes were determined using propidium iodine and acridine orange stain and observed under a fluorescent microscope. The percentage of viable lymphocytes of the treatment group(71.0%; p = 0.03) was significantly higher than the positive control group. The results showed that C. vulgaris possessed radioprotective effects because the lymphocyte actin was not damaged. The radioprotection effects could be due to the presence of antioxidants in C. vulgaris.
format	Article
author	Khairul Osman, Norashikin Md Saad, Ezlan Elias, Siti Fatimah Ibrahim, Jamaludin Mohamed, Proom Proomwichit,
spellingShingle	Khairul Osman, Norashikin Md Saad, Ezlan Elias, Siti Fatimah Ibrahim, Jamaludin Mohamed, Proom Proomwichit, Protective effects of Citrullus vulgaris on Irradiated Lymphocyte Sub-membrane
author_facet	Khairul Osman, Norashikin Md Saad, Ezlan Elias, Siti Fatimah Ibrahim, Jamaludin Mohamed, Proom Proomwichit,
author_sort	Khairul Osman,
title	Protective effects of Citrullus vulgaris on Irradiated Lymphocyte Sub-membrane
title_short	Protective effects of Citrullus vulgaris on Irradiated Lymphocyte Sub-membrane
title_full	Protective effects of Citrullus vulgaris on Irradiated Lymphocyte Sub-membrane
title_fullStr	Protective effects of Citrullus vulgaris on Irradiated Lymphocyte Sub-membrane
title_full_unstemmed	Protective effects of Citrullus vulgaris on Irradiated Lymphocyte Sub-membrane
title_sort	protective effects of citrullus vulgaris on irradiated lymphocyte sub-membrane
publisher	penerbit ukm
publishDate	2005
url	http://journalarticle.ukm.my/978/ http://journalarticle.ukm.my/978/ http://journalarticle.ukm.my/978/1/jurnal31.pdf
first_indexed	2023-09-18T19:32:03Z
last_indexed	2023-09-18T19:32:03Z
_version_	1777405026023505920

Protective effects of Citrullus vulgaris on Irradiated Lymphocyte Sub-membrane

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