A New Neuron Ion Channel Model with Noisy Input Current

The data processing fundamental problem affects all aspects of nervous-system function by the noise of ion channels. The conducting and non conducting of ion channels depends on random transitions of channel noise, which affect the states of several numbers of gates in every single individual ion ch...

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Main Authors:	Khudhur, Ahmed Mahmood, Abdalla, Ahmed N.
Format:	Article
Language:	English
Published:	Penerbit Universiti Malaysia Pahang 2015
Subjects:	T Technology (General)
Online Access:	http://umpir.ump.edu.my/id/eprint/10628/ http://umpir.ump.edu.my/id/eprint/10628/ http://umpir.ump.edu.my/id/eprint/10628/ http://umpir.ump.edu.my/id/eprint/10628/1/A%20New%20Neuron%20Ion%20Channel%20Model%20with%20Noisy%20Input%20Current.pdf

id	ump-10628
recordtype	eprints
spelling	ump-106282018-10-03T07:32:51Z http://umpir.ump.edu.my/id/eprint/10628/ A New Neuron Ion Channel Model with Noisy Input Current Khudhur, Ahmed Mahmood Abdalla, Ahmed N. T Technology (General) The data processing fundamental problem affects all aspects of nervous-system function by the noise of ion channels. The conducting and non conducting of ion channels depends on random transitions of channel noise, which affect the states of several numbers of gates in every single individual ion channel. This paper, introduce a new ion channel model in the neuron with noisy input current as approximations of the HH model. It briefly introduces the ion channel based on stochastic Hodgkin-Huxley model. The method is able to fully constrain the HH model and obtain all models capable of reproducing the data. Therefore, this method overcomes the limitations of other parameter estimation methods. The stochastic Markov process method is simply applied to simulate each gate individually to determine the relationship between channel noise and the spike frequency. Penerbit Universiti Malaysia Pahang 2015 Article PeerReviewed application/pdf en cc_by http://umpir.ump.edu.my/id/eprint/10628/1/A%20New%20Neuron%20Ion%20Channel%20Model%20with%20Noisy%20Input%20Current.pdf Khudhur, Ahmed Mahmood and Abdalla, Ahmed N. (2015) A New Neuron Ion Channel Model with Noisy Input Current. International Journal of Engineering Technology And Sciences (IJETS), 3 (1). pp. 1-7. ISSN 2289-697X http://ijets.ump.edu.my/images/archive/Vol3-new/5.pdf DOI: 10.15282/ijets.3.2015.1.5.1022
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	T Technology (General)
spellingShingle	T Technology (General) Khudhur, Ahmed Mahmood Abdalla, Ahmed N. A New Neuron Ion Channel Model with Noisy Input Current
description	The data processing fundamental problem affects all aspects of nervous-system function by the noise of ion channels. The conducting and non conducting of ion channels depends on random transitions of channel noise, which affect the states of several numbers of gates in every single individual ion channel. This paper, introduce a new ion channel model in the neuron with noisy input current as approximations of the HH model. It briefly introduces the ion channel based on stochastic Hodgkin-Huxley model. The method is able to fully constrain the HH model and obtain all models capable of reproducing the data. Therefore, this method overcomes the limitations of other parameter estimation methods. The stochastic Markov process method is simply applied to simulate each gate individually to determine the relationship between channel noise and the spike frequency.
format	Article
author	Khudhur, Ahmed Mahmood Abdalla, Ahmed N.
author_facet	Khudhur, Ahmed Mahmood Abdalla, Ahmed N.
author_sort	Khudhur, Ahmed Mahmood
title	A New Neuron Ion Channel Model with Noisy Input Current
title_short	A New Neuron Ion Channel Model with Noisy Input Current
title_full	A New Neuron Ion Channel Model with Noisy Input Current
title_fullStr	A New Neuron Ion Channel Model with Noisy Input Current
title_full_unstemmed	A New Neuron Ion Channel Model with Noisy Input Current
title_sort	new neuron ion channel model with noisy input current
publisher	Penerbit Universiti Malaysia Pahang
publishDate	2015
url	http://umpir.ump.edu.my/id/eprint/10628/ http://umpir.ump.edu.my/id/eprint/10628/ http://umpir.ump.edu.my/id/eprint/10628/ http://umpir.ump.edu.my/id/eprint/10628/1/A%20New%20Neuron%20Ion%20Channel%20Model%20with%20Noisy%20Input%20Current.pdf
first_indexed	2023-09-18T22:10:26Z
last_indexed	2023-09-18T22:10:26Z
_version_	1777414991207464960

A New Neuron Ion Channel Model with Noisy Input Current

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