Biochip Development for Biological Cells Manipulation Using DEP

Biochip Development for Biological Cells Manipulation Using DEP

Biochip is a technology platform that has become the medium of researchers in carrying out the analysis of biological cells such as sorting, trapping and screening of biological within a few seconds. To conduct analysis on biological cells, appropriate manipulation techniques are required. In this...

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Main Authors: Siti Nursyahirah, Ahmad Latfi, Fahmi, Samsuri
Format: Article
Language:English
Published: Asian Research Publishing Network (ARPN) 2015
Subjects:
TK Electrical engineering. Electronics Nuclear engineering
Online Access:http://umpir.ump.edu.my/id/eprint/11295/
http://umpir.ump.edu.my/id/eprint/11295/
http://umpir.ump.edu.my/id/eprint/11295/1/Biochip%20Development%20for%20Biological%20Cells%20Manipulation%20Using%20DEP.pdf
id ump-11295
recordtype eprints
spelling ump-112952018-05-18T06:03:33Z http://umpir.ump.edu.my/id/eprint/11295/ Biochip Development for Biological Cells Manipulation Using DEP Siti Nursyahirah, Ahmad Latfi Fahmi, Samsuri TK Electrical engineering. Electronics Nuclear engineering Biochip is a technology platform that has become the medium of researchers in carrying out the analysis of biological cells such as sorting, trapping and screening of biological within a few seconds. To conduct analysis on biological cells, appropriate manipulation techniques are required. In this research, a Dielectrophoresis force (DEP) manipulation technique was used by applying non-uniform AC electric fields generated by the microeletrodes designed. For carrying out on one of the main objectives of this study, COMSOL Multiphysics 4.4 software was used in this study in which the ring planar microarray microelectrodes pattern was designed to investigate the distribution of the electric field resulting from the microelectrodes designed. Results show the highest electric field strength occurs at the end of the microelectrode tip at the same time the lowest electric field region can be seen at the microcavity centre. Cell trapping may also occur in the central part of the micro-cavities with negative dielectrophoresis (nDEP) in which cells will become interested in the low electric field. Asian Research Publishing Network (ARPN) 2015 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/11295/1/Biochip%20Development%20for%20Biological%20Cells%20Manipulation%20Using%20DEP.pdf Siti Nursyahirah, Ahmad Latfi and Fahmi, Samsuri (2015) Biochip Development for Biological Cells Manipulation Using DEP. ARPN Journal of Engineering and Applied Sciences, 10 (22). 17091 -17094. ISSN 1819-6608 http://www.arpnjournals.org/jeas/research_papers/rp_2015/jeas_1215_3133.pdf
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
topic TK Electrical engineering. Electronics Nuclear engineering
spellingShingle TK Electrical engineering. Electronics Nuclear engineering
Siti Nursyahirah, Ahmad Latfi
Fahmi, Samsuri
Biochip Development for Biological Cells Manipulation Using DEP
description Biochip is a technology platform that has become the medium of researchers in carrying out the analysis of biological cells such as sorting, trapping and screening of biological within a few seconds. To conduct analysis on biological cells, appropriate manipulation techniques are required. In this research, a Dielectrophoresis force (DEP) manipulation technique was used by applying non-uniform AC electric fields generated by the microeletrodes designed. For carrying out on one of the main objectives of this study, COMSOL Multiphysics 4.4 software was used in this study in which the ring planar microarray microelectrodes pattern was designed to investigate the distribution of the electric field resulting from the microelectrodes designed. Results show the highest electric field strength occurs at the end of the microelectrode tip at the same time the lowest electric field region can be seen at the microcavity centre. Cell trapping may also occur in the central part of the micro-cavities with negative dielectrophoresis (nDEP) in which cells will become interested in the low electric field.
format Article
author Siti Nursyahirah, Ahmad Latfi
Fahmi, Samsuri
author_facet Siti Nursyahirah, Ahmad Latfi
Fahmi, Samsuri
author_sort Siti Nursyahirah, Ahmad Latfi
title Biochip Development for Biological Cells Manipulation Using DEP
title_short Biochip Development for Biological Cells Manipulation Using DEP
title_full Biochip Development for Biological Cells Manipulation Using DEP
title_fullStr Biochip Development for Biological Cells Manipulation Using DEP
title_full_unstemmed Biochip Development for Biological Cells Manipulation Using DEP
title_sort biochip development for biological cells manipulation using dep
publisher Asian Research Publishing Network (ARPN)
publishDate 2015
url http://umpir.ump.edu.my/id/eprint/11295/
http://umpir.ump.edu.my/id/eprint/11295/
http://umpir.ump.edu.my/id/eprint/11295/1/Biochip%20Development%20for%20Biological%20Cells%20Manipulation%20Using%20DEP.pdf
first_indexed 2023-09-18T22:11:53Z
last_indexed 2023-09-18T22:11:53Z
_version_ 1777415081866297344

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