Optimisation of Solid Liquid Extraction of Orthosiphon stamineus Leaves using Response Surface Methodology Technique

Optimisation of Solid Liquid Extraction of Orthosiphon stamineus Leaves using Response Surface Methodology Technique

Orthosiphon stamineus is one of the popular medicinal plants in Southeast Asia. O. stamineus leaves are used in numerous applications related to medicinal purposes and are believed to cure certain health conditions such as hypertension, gout and fever. The aim of this study was to investigate the...

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Main Authors: A. R., Mohd Farhan, K. Y., Pin, M. S., Zamree, Luqman Chuah, Abdullah, Nazira, Mahmud
Format: Article
Language:English
English
Published: Universiti Putra Malaysia Press 2015
Subjects:
Q Science (General)
Online Access:http://umpir.ump.edu.my/id/eprint/11334/
http://umpir.ump.edu.my/id/eprint/11334/
http://umpir.ump.edu.my/id/eprint/11334/1/Optimisation%20of%20Solid%20Liquid%20Extraction%20of%20Orthosiphon%20stamineus%20Leaves%20using%20Response%20Surface%20Methodology%20Technique.pdf
http://umpir.ump.edu.my/id/eprint/11334/7/Optimisation%20of%20Solid%20Liquid%20Extraction%20of%20Orthosiphon%20stamineus%20Leaves%20using%20Response%20Surface%20Methodology%20Technique.pdf
id ump-11334
recordtype eprints
spelling ump-113342015-12-18T06:53:37Z http://umpir.ump.edu.my/id/eprint/11334/ Optimisation of Solid Liquid Extraction of Orthosiphon stamineus Leaves using Response Surface Methodology Technique A. R., Mohd Farhan K. Y., Pin M. S., Zamree Luqman Chuah, Abdullah Nazira, Mahmud Q Science (General) Orthosiphon stamineus is one of the popular medicinal plants in Southeast Asia. O. stamineus leaves are used in numerous applications related to medicinal purposes and are believed to cure certain health conditions such as hypertension, gout and fever. The aim of this study was to investigate the effect of three parameters involved in extraction process including extraction temperature, extraction duration and solvent to solid ratio on extraction yield, antioxidant activity and referral markers of O. stamineus leaves. The optimisation of extraction processes was evaluated with the aid of Design-Expert software using response surface methodology (RSM). The optimum extraction parameter for O. stamineus leaves were recorded at the extraction temperature of 60°C, 30:1 (ml:g) solvent to solid ratio and 6 hours extraction duration with 30Wt% extract, 67 and 1 mg/L concentration of Rosmarinic acid and Sinensetin, respectively. Antioxidant activity for optimized extract is 96.56% and 91.51% of SOD and DPPH method, respectively. Universiti Putra Malaysia Press 2015 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/11334/1/Optimisation%20of%20Solid%20Liquid%20Extraction%20of%20Orthosiphon%20stamineus%20Leaves%20using%20Response%20Surface%20Methodology%20Technique.pdf application/pdf en http://umpir.ump.edu.my/id/eprint/11334/7/Optimisation%20of%20Solid%20Liquid%20Extraction%20of%20Orthosiphon%20stamineus%20Leaves%20using%20Response%20Surface%20Methodology%20Technique.pdf A. R., Mohd Farhan and K. Y., Pin and M. S., Zamree and Luqman Chuah, Abdullah and Nazira, Mahmud (2015) Optimisation of Solid Liquid Extraction of Orthosiphon stamineus Leaves using Response Surface Methodology Technique. Pertanika Journal of Tropical Agricultural Science, 38 (2). pp. 259-270. ISSN 1511-3701 (Print); 2231-8542 (Online) http://www.pertanika.upm.edu.my/Pertanika%20PAPERS/JTAS%20Vol.%2038%20(2)%20May.%202015/08%20Page%20259-270%20(JTAS%200607-2014).pdf
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
English
topic Q Science (General)
spellingShingle Q Science (General)
A. R., Mohd Farhan
K. Y., Pin
M. S., Zamree
Luqman Chuah, Abdullah
Nazira, Mahmud
Optimisation of Solid Liquid Extraction of Orthosiphon stamineus Leaves using Response Surface Methodology Technique
description Orthosiphon stamineus is one of the popular medicinal plants in Southeast Asia. O. stamineus leaves are used in numerous applications related to medicinal purposes and are believed to cure certain health conditions such as hypertension, gout and fever. The aim of this study was to investigate the effect of three parameters involved in extraction process including extraction temperature, extraction duration and solvent to solid ratio on extraction yield, antioxidant activity and referral markers of O. stamineus leaves. The optimisation of extraction processes was evaluated with the aid of Design-Expert software using response surface methodology (RSM). The optimum extraction parameter for O. stamineus leaves were recorded at the extraction temperature of 60°C, 30:1 (ml:g) solvent to solid ratio and 6 hours extraction duration with 30Wt% extract, 67 and 1 mg/L concentration of Rosmarinic acid and Sinensetin, respectively. Antioxidant activity for optimized extract is 96.56% and 91.51% of SOD and DPPH method, respectively.
format Article
author A. R., Mohd Farhan
K. Y., Pin
M. S., Zamree
Luqman Chuah, Abdullah
Nazira, Mahmud
author_facet A. R., Mohd Farhan
K. Y., Pin
M. S., Zamree
Luqman Chuah, Abdullah
Nazira, Mahmud
author_sort A. R., Mohd Farhan
title Optimisation of Solid Liquid Extraction of Orthosiphon stamineus Leaves using Response Surface Methodology Technique
title_short Optimisation of Solid Liquid Extraction of Orthosiphon stamineus Leaves using Response Surface Methodology Technique
title_full Optimisation of Solid Liquid Extraction of Orthosiphon stamineus Leaves using Response Surface Methodology Technique
title_fullStr Optimisation of Solid Liquid Extraction of Orthosiphon stamineus Leaves using Response Surface Methodology Technique
title_full_unstemmed Optimisation of Solid Liquid Extraction of Orthosiphon stamineus Leaves using Response Surface Methodology Technique
title_sort optimisation of solid liquid extraction of orthosiphon stamineus leaves using response surface methodology technique
publisher Universiti Putra Malaysia Press
publishDate 2015
url http://umpir.ump.edu.my/id/eprint/11334/
http://umpir.ump.edu.my/id/eprint/11334/
http://umpir.ump.edu.my/id/eprint/11334/1/Optimisation%20of%20Solid%20Liquid%20Extraction%20of%20Orthosiphon%20stamineus%20Leaves%20using%20Response%20Surface%20Methodology%20Technique.pdf
http://umpir.ump.edu.my/id/eprint/11334/7/Optimisation%20of%20Solid%20Liquid%20Extraction%20of%20Orthosiphon%20stamineus%20Leaves%20using%20Response%20Surface%20Methodology%20Technique.pdf
first_indexed 2023-09-18T22:11:57Z
last_indexed 2023-09-18T22:11:57Z
_version_ 1777415086864859136

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