Modelling the Cervical Cancer Growth Process by Stochastic Delay Differential Equations

In this paper, the uncontrolled environmental factors are perturbed into the growth rate deceleration factor of the Gompertzian deterministic model. The growth process under Gompertz’s law is considered, thus lead to stochastic differential equations of Gompertzian with time delay. The Gompertzian d...

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Main Authors: Mazma Syahidatul Ayuni, Mazlan, Norhayati, Rosli, Nina Suhaity, Azmi, Arifah, Bahar
Format: Article
Language:English
English
Published: Universiti Kebangsaan Malaysia 2015
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/12712/
http://umpir.ump.edu.my/id/eprint/12712/
http://umpir.ump.edu.my/id/eprint/12712/1/Sains%20Malaysiana%20Norhayati%20Rosli.pdf
http://umpir.ump.edu.my/id/eprint/12712/7/fist-2015-hayati-Modelling%20the%20Cervical%20Cancer.pdf
id ump-12712
recordtype eprints
spelling ump-127122018-01-25T02:30:40Z http://umpir.ump.edu.my/id/eprint/12712/ Modelling the Cervical Cancer Growth Process by Stochastic Delay Differential Equations Mazma Syahidatul Ayuni, Mazlan Norhayati, Rosli Nina Suhaity, Azmi Arifah, Bahar QA Mathematics In this paper, the uncontrolled environmental factors are perturbed into the growth rate deceleration factor of the Gompertzian deterministic model. The growth process under Gompertz’s law is considered, thus lead to stochastic differential equations of Gompertzian with time delay. The Gompertzian deterministic model has proven to fit well with the clinical data of cancerous growth, however the performance of stochastic model towards clinical data is yet to be confirmed. The prediction quality of stochastic model is evaluated by comparing the simulated results with the clinical data of cervical cancer growth. The parameter estimation of stochastic models is computed by using simulated maximum likelihood method. 4-stage stochastic Runge-Kutta is applied to simulate the solution of stochastic model. Low values of root mean-square error (RMSE) of Gompertzian model with random effect indicate good fits. Universiti Kebangsaan Malaysia 2015-08 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/12712/1/Sains%20Malaysiana%20Norhayati%20Rosli.pdf application/pdf en http://umpir.ump.edu.my/id/eprint/12712/7/fist-2015-hayati-Modelling%20the%20Cervical%20Cancer.pdf Mazma Syahidatul Ayuni, Mazlan and Norhayati, Rosli and Nina Suhaity, Azmi and Arifah, Bahar (2015) Modelling the Cervical Cancer Growth Process by Stochastic Delay Differential Equations. Sains Malaysiana, 44 (8). pp. 1153-1157. ISSN 0126-6039 http://www.ukm.my/jsm/pdf_files/SM-PDF-44-8-2015/11%20Mazma%20Syahidatul.pdf
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
English
topic QA Mathematics
spellingShingle QA Mathematics
Mazma Syahidatul Ayuni, Mazlan
Norhayati, Rosli
Nina Suhaity, Azmi
Arifah, Bahar
Modelling the Cervical Cancer Growth Process by Stochastic Delay Differential Equations
description In this paper, the uncontrolled environmental factors are perturbed into the growth rate deceleration factor of the Gompertzian deterministic model. The growth process under Gompertz’s law is considered, thus lead to stochastic differential equations of Gompertzian with time delay. The Gompertzian deterministic model has proven to fit well with the clinical data of cancerous growth, however the performance of stochastic model towards clinical data is yet to be confirmed. The prediction quality of stochastic model is evaluated by comparing the simulated results with the clinical data of cervical cancer growth. The parameter estimation of stochastic models is computed by using simulated maximum likelihood method. 4-stage stochastic Runge-Kutta is applied to simulate the solution of stochastic model. Low values of root mean-square error (RMSE) of Gompertzian model with random effect indicate good fits.
format Article
author Mazma Syahidatul Ayuni, Mazlan
Norhayati, Rosli
Nina Suhaity, Azmi
Arifah, Bahar
author_facet Mazma Syahidatul Ayuni, Mazlan
Norhayati, Rosli
Nina Suhaity, Azmi
Arifah, Bahar
author_sort Mazma Syahidatul Ayuni, Mazlan
title Modelling the Cervical Cancer Growth Process by Stochastic Delay Differential Equations
title_short Modelling the Cervical Cancer Growth Process by Stochastic Delay Differential Equations
title_full Modelling the Cervical Cancer Growth Process by Stochastic Delay Differential Equations
title_fullStr Modelling the Cervical Cancer Growth Process by Stochastic Delay Differential Equations
title_full_unstemmed Modelling the Cervical Cancer Growth Process by Stochastic Delay Differential Equations
title_sort modelling the cervical cancer growth process by stochastic delay differential equations
publisher Universiti Kebangsaan Malaysia
publishDate 2015
url http://umpir.ump.edu.my/id/eprint/12712/
http://umpir.ump.edu.my/id/eprint/12712/
http://umpir.ump.edu.my/id/eprint/12712/1/Sains%20Malaysiana%20Norhayati%20Rosli.pdf
http://umpir.ump.edu.my/id/eprint/12712/7/fist-2015-hayati-Modelling%20the%20Cervical%20Cancer.pdf
first_indexed 2023-09-18T22:14:35Z
last_indexed 2023-09-18T22:14:35Z
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