In-vitro Antioxidant Potential of the Flavonoid Glycosides from Cassia tora linn. Leaves

The present study aimed to study the anti-oxidant potential of isolated flavonoids from the ethanol extract (70%v/v) of Cassia tora leaves. Three flavonoids were isolated viz Luteolin-7-O-β-glucopyranoside (I), quercetin-3-O-β-d-glucuronide (II) and Formononetin-7-O-β-D-Glucoside (III) from the etha...

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Main Authors:	Vijayalakshmi, A., Jayakumari, S., Masilamani, K.
Format:	Article
Language:	English English
Published:	Penerbit Universiti Malaysia Pahang 2016
Subjects:	T Technology (General)
Online Access:	http://umpir.ump.edu.my/id/eprint/13806/ http://umpir.ump.edu.my/id/eprint/13806/ http://umpir.ump.edu.my/id/eprint/13806/ http://umpir.ump.edu.my/id/eprint/13806/1/In-vitro%20antioxidant%20potential%20of%20the%20flavonoid%20glycosides%20from%20Cassia%20tora%20linn.%20Leaves.pdf http://umpir.ump.edu.my/id/eprint/13806/7/ftech-2016-masilamani-Invitro%20antioxidant%20potential1.pdf

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spelling	ump-138062018-02-01T06:47:13Z http://umpir.ump.edu.my/id/eprint/13806/ In-vitro Antioxidant Potential of the Flavonoid Glycosides from Cassia tora linn. Leaves Vijayalakshmi, A. Jayakumari, S. Masilamani, K. T Technology (General) The present study aimed to study the anti-oxidant potential of isolated flavonoids from the ethanol extract (70%v/v) of Cassia tora leaves. Three flavonoids were isolated viz Luteolin-7-O-β-glucopyranoside (I), quercetin-3-O-β-d-glucuronide (II) and Formononetin-7-O-β-D-Glucoside (III) from the ethanol extract (70%v/v) of Cassia tora leaves in the previous study. A comprehensive study on the phytochemical contents - total phenolic content and flavonoid content was accessed using Folin-Denis and AlCl3 method respectively. The antioxidant potential of the samples was evaluated using inhibition of hydroxyl radical, 2,2-diphenyl-1- picrylhydrazyl (DPPH), and nitric oxide scavenging methods. The total phenolic content and flavonoid content was found to be 18.60 % w/w and 9.5% w/w respectively. The IC50 values of ethanol extract against hydroxyl, DPPH and nitric oxide radical were found to be 270 µg/mL, 190 µg/mL and 130 µg/mL respectively. The radical scavenging activity of the isolated flavonoids decreased in the following order: quercetin (IC50 values 15, 14, 18 µg/mL) >formononetin (IC50 values 19, 21, 14 µg/mL) > luteolin (IC50 values 20, 23, 18 µg/mL) respectively. Index terms - Cassia tora, flavonoids, HPTLC, antioxidant Penerbit Universiti Malaysia Pahang 2016 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/13806/1/In-vitro%20antioxidant%20potential%20of%20the%20flavonoid%20glycosides%20from%20Cassia%20tora%20linn.%20Leaves.pdf application/pdf en http://umpir.ump.edu.my/id/eprint/13806/7/ftech-2016-masilamani-Invitro%20antioxidant%20potential1.pdf Vijayalakshmi, A. and Jayakumari, S. and Masilamani, K. (2016) In-vitro Antioxidant Potential of the Flavonoid Glycosides from Cassia tora linn. Leaves. International Journal of Engineering Technology And Sciences (IJETS), 5 (1). pp. 19-26. ISSN 2289-697X http://ijets.ump.edu.my/images/archive/Vol5/IJETS3.pdf DOI: 10.15282/ijets.5.2016.1.3.1042
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English English
topic	T Technology (General)
spellingShingle	T Technology (General) Vijayalakshmi, A. Jayakumari, S. Masilamani, K. In-vitro Antioxidant Potential of the Flavonoid Glycosides from Cassia tora linn. Leaves
description	The present study aimed to study the anti-oxidant potential of isolated flavonoids from the ethanol extract (70%v/v) of Cassia tora leaves. Three flavonoids were isolated viz Luteolin-7-O-β-glucopyranoside (I), quercetin-3-O-β-d-glucuronide (II) and Formononetin-7-O-β-D-Glucoside (III) from the ethanol extract (70%v/v) of Cassia tora leaves in the previous study. A comprehensive study on the phytochemical contents - total phenolic content and flavonoid content was accessed using Folin-Denis and AlCl3 method respectively. The antioxidant potential of the samples was evaluated using inhibition of hydroxyl radical, 2,2-diphenyl-1- picrylhydrazyl (DPPH), and nitric oxide scavenging methods. The total phenolic content and flavonoid content was found to be 18.60 % w/w and 9.5% w/w respectively. The IC50 values of ethanol extract against hydroxyl, DPPH and nitric oxide radical were found to be 270 µg/mL, 190 µg/mL and 130 µg/mL respectively. The radical scavenging activity of the isolated flavonoids decreased in the following order: quercetin (IC50 values 15, 14, 18 µg/mL) >formononetin (IC50 values 19, 21, 14 µg/mL) > luteolin (IC50 values 20, 23, 18 µg/mL) respectively. Index terms - Cassia tora, flavonoids, HPTLC, antioxidant
format	Article
author	Vijayalakshmi, A. Jayakumari, S. Masilamani, K.
author_facet	Vijayalakshmi, A. Jayakumari, S. Masilamani, K.
author_sort	Vijayalakshmi, A.
title	In-vitro Antioxidant Potential of the Flavonoid Glycosides from Cassia tora linn. Leaves
title_short	In-vitro Antioxidant Potential of the Flavonoid Glycosides from Cassia tora linn. Leaves
title_full	In-vitro Antioxidant Potential of the Flavonoid Glycosides from Cassia tora linn. Leaves
title_fullStr	In-vitro Antioxidant Potential of the Flavonoid Glycosides from Cassia tora linn. Leaves
title_full_unstemmed	In-vitro Antioxidant Potential of the Flavonoid Glycosides from Cassia tora linn. Leaves
title_sort	in-vitro antioxidant potential of the flavonoid glycosides from cassia tora linn. leaves
publisher	Penerbit Universiti Malaysia Pahang
publishDate	2016
url	http://umpir.ump.edu.my/id/eprint/13806/ http://umpir.ump.edu.my/id/eprint/13806/ http://umpir.ump.edu.my/id/eprint/13806/ http://umpir.ump.edu.my/id/eprint/13806/1/In-vitro%20antioxidant%20potential%20of%20the%20flavonoid%20glycosides%20from%20Cassia%20tora%20linn.%20Leaves.pdf http://umpir.ump.edu.my/id/eprint/13806/7/ftech-2016-masilamani-Invitro%20antioxidant%20potential1.pdf
first_indexed	2023-09-18T22:16:50Z
last_indexed	2023-09-18T22:16:50Z
_version_	1777415393655128064

In-vitro Antioxidant Potential of the Flavonoid Glycosides from Cassia tora linn. Leaves

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