Flavokawain B Induced cytotoxicity in Two Breast Cancer Cell Lines, MCF-7 and MDA-MB231 and Inhibited the Metastatic Potential of MDA-MB231 via the Regulation of Several Tyrosine Kinases In vitro

Background The kava-kava plant (Piper methysticum) is traditionally consumed by the pacific islanders and has been linked to be involved in several biological activities. Flavokawain B is a unique chalcone, which can be found in the roots of the kava-kava plant. In this study, the operational mec...

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Main Authors:	Nadiah, Abu, Akhtar, Muhammad Nadeem, Swee, K. Yeap, Kian, Lam Lim, Wan, Yong Ho, Mohd Puad, Abdullah, Chai, Ling Ho, Abdul Rahman, Omar, Jamil, Ismail, Noorjahan Banu, Alitheen
Format:	Article
Language:	English
Published:	BioMed Central Ltd. 2016
Subjects:	QR Microbiology
Online Access:	http://umpir.ump.edu.my/id/eprint/16809/ http://umpir.ump.edu.my/id/eprint/16809/ http://umpir.ump.edu.my/id/eprint/16809/ http://umpir.ump.edu.my/id/eprint/16809/1/fist-2016-nadeem-Flavokawain%20B%20induced1.pdf

id	ump-16809
recordtype	eprints
spelling	ump-168092017-11-17T06:46:29Z http://umpir.ump.edu.my/id/eprint/16809/ Flavokawain B Induced cytotoxicity in Two Breast Cancer Cell Lines, MCF-7 and MDA-MB231 and Inhibited the Metastatic Potential of MDA-MB231 via the Regulation of Several Tyrosine Kinases In vitro Nadiah, Abu Akhtar, Muhammad Nadeem Swee, K. Yeap Kian, Lam Lim Wan, Yong Ho Mohd Puad, Abdullah Chai, Ling Ho Abdul Rahman, Omar Jamil, Ismail Noorjahan Banu, Alitheen QR Microbiology Background The kava-kava plant (Piper methysticum) is traditionally consumed by the pacific islanders and has been linked to be involved in several biological activities. Flavokawain B is a unique chalcone, which can be found in the roots of the kava-kava plant. In this study, the operational mechanism of the anti-cancer activity of a synthetic Flavokawain B (FKB) on two breast cancer cell lines, MCF-7 and MDA-MB231 was investigated. BioMed Central Ltd. 2016 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/16809/1/fist-2016-nadeem-Flavokawain%20B%20induced1.pdf Nadiah, Abu and Akhtar, Muhammad Nadeem and Swee, K. Yeap and Kian, Lam Lim and Wan, Yong Ho and Mohd Puad, Abdullah and Chai, Ling Ho and Abdul Rahman, Omar and Jamil, Ismail and Noorjahan Banu, Alitheen (2016) Flavokawain B Induced cytotoxicity in Two Breast Cancer Cell Lines, MCF-7 and MDA-MB231 and Inhibited the Metastatic Potential of MDA-MB231 via the Regulation of Several Tyrosine Kinases In vitro. BMC Complementary and Alternative Medicine, 16 (86). pp. 1-14. ISSN 1472-6882 http://doi.org/10.1186/s12906-016-1046-8 doi: 10.1186/s12906-016-1046-8
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	QR Microbiology
spellingShingle	QR Microbiology Nadiah, Abu Akhtar, Muhammad Nadeem Swee, K. Yeap Kian, Lam Lim Wan, Yong Ho Mohd Puad, Abdullah Chai, Ling Ho Abdul Rahman, Omar Jamil, Ismail Noorjahan Banu, Alitheen Flavokawain B Induced cytotoxicity in Two Breast Cancer Cell Lines, MCF-7 and MDA-MB231 and Inhibited the Metastatic Potential of MDA-MB231 via the Regulation of Several Tyrosine Kinases In vitro
description	Background The kava-kava plant (Piper methysticum) is traditionally consumed by the pacific islanders and has been linked to be involved in several biological activities. Flavokawain B is a unique chalcone, which can be found in the roots of the kava-kava plant. In this study, the operational mechanism of the anti-cancer activity of a synthetic Flavokawain B (FKB) on two breast cancer cell lines, MCF-7 and MDA-MB231 was investigated.
format	Article
author	Nadiah, Abu Akhtar, Muhammad Nadeem Swee, K. Yeap Kian, Lam Lim Wan, Yong Ho Mohd Puad, Abdullah Chai, Ling Ho Abdul Rahman, Omar Jamil, Ismail Noorjahan Banu, Alitheen
author_facet	Nadiah, Abu Akhtar, Muhammad Nadeem Swee, K. Yeap Kian, Lam Lim Wan, Yong Ho Mohd Puad, Abdullah Chai, Ling Ho Abdul Rahman, Omar Jamil, Ismail Noorjahan Banu, Alitheen
author_sort	Nadiah, Abu
title	Flavokawain B Induced cytotoxicity in Two Breast Cancer Cell Lines, MCF-7 and MDA-MB231 and Inhibited the Metastatic Potential of MDA-MB231 via the Regulation of Several Tyrosine Kinases In vitro
title_short	Flavokawain B Induced cytotoxicity in Two Breast Cancer Cell Lines, MCF-7 and MDA-MB231 and Inhibited the Metastatic Potential of MDA-MB231 via the Regulation of Several Tyrosine Kinases In vitro
title_full	Flavokawain B Induced cytotoxicity in Two Breast Cancer Cell Lines, MCF-7 and MDA-MB231 and Inhibited the Metastatic Potential of MDA-MB231 via the Regulation of Several Tyrosine Kinases In vitro
title_fullStr	Flavokawain B Induced cytotoxicity in Two Breast Cancer Cell Lines, MCF-7 and MDA-MB231 and Inhibited the Metastatic Potential of MDA-MB231 via the Regulation of Several Tyrosine Kinases In vitro
title_full_unstemmed	Flavokawain B Induced cytotoxicity in Two Breast Cancer Cell Lines, MCF-7 and MDA-MB231 and Inhibited the Metastatic Potential of MDA-MB231 via the Regulation of Several Tyrosine Kinases In vitro
title_sort	flavokawain b induced cytotoxicity in two breast cancer cell lines, mcf-7 and mda-mb231 and inhibited the metastatic potential of mda-mb231 via the regulation of several tyrosine kinases in vitro
publisher	BioMed Central Ltd.
publishDate	2016
url	http://umpir.ump.edu.my/id/eprint/16809/ http://umpir.ump.edu.my/id/eprint/16809/ http://umpir.ump.edu.my/id/eprint/16809/ http://umpir.ump.edu.my/id/eprint/16809/1/fist-2016-nadeem-Flavokawain%20B%20induced1.pdf
first_indexed	2023-09-18T22:22:49Z
last_indexed	2023-09-18T22:22:49Z
_version_	1777415769619955712

Flavokawain B Induced cytotoxicity in Two Breast Cancer Cell Lines, MCF-7 and MDA-MB231 and Inhibited the Metastatic Potential of MDA-MB231 via the Regulation of Several Tyrosine Kinases In vitro

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