Optimization of Red Pigment Production By Monascus Purpureus FTC 5356 Using Response Surface Methodology

Important factor such as certain environmental conditions and nutrients as a source for the medium are significant for successful growth and reproduction of microorganism. Manipulation of the factor is the most effective way to stimulate the growth of the microorganism in subsequent optimize the qua...

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Main Authors:	Nor Farhana, Hamid, Farhan, Mohd Said
Format:	Article
Language:	English
Published:	IIUM, Malaysia 2018
Subjects:	T Technology (General)
Online Access:	http://umpir.ump.edu.my/id/eprint/17901/ http://umpir.ump.edu.my/id/eprint/17901/ http://umpir.ump.edu.my/id/eprint/17901/ http://umpir.ump.edu.my/id/eprint/17901/1/Optimization%20of%20Red%20Pigment%20Production%20By%20Monascus-fkksa-2018.pdf

id	ump-17901
recordtype	eprints
spelling	ump-179012018-06-04T06:48:35Z http://umpir.ump.edu.my/id/eprint/17901/ Optimization of Red Pigment Production By Monascus Purpureus FTC 5356 Using Response Surface Methodology Nor Farhana, Hamid Farhan, Mohd Said T Technology (General) Important factor such as certain environmental conditions and nutrients as a source for the medium are significant for successful growth and reproduction of microorganism. Manipulation of the factor is the most effective way to stimulate the growth of the microorganism in subsequent optimize the quality of the product. In this study, Central Composite Design (CCD) of Response Surface Methodology (RSM) was used to optimize the production of red pigment by Monascus purpureus FTC 5356 using oil palm frond (OPF) as a substrate in solid state fermentation (SSF). The data was analyzed using Design Expert Software. The optimum combination predicted via RSM was confirmed through experimental. The interaction between three variables ie; initial moisture content (%), initial pH value (pH), and peptone concentration (%) was studied and modeled. The statistical analysis of the results showed that in the range studied, optimal condition for red pigment production (47 AU/g) with the biomass (425.1 mg/g) was 55% initial moisture content, 3% of peptone concentration and pH 3 for initial pH value of the substrate. The results of RSM showed that the initial pH value had significant effect on red pigment production (P-value <0.05). The validation of these results was also conducted by carried out fermentation with predicted condition and it was found that there are 0.373% higher in values of experimental result compared to the predicted values. IIUM, Malaysia 2018 Article PeerReviewed application/pdf en cc_by_nc http://umpir.ump.edu.my/id/eprint/17901/1/Optimization%20of%20Red%20Pigment%20Production%20By%20Monascus-fkksa-2018.pdf Nor Farhana, Hamid and Farhan, Mohd Said (2018) Optimization of Red Pigment Production By Monascus Purpureus FTC 5356 Using Response Surface Methodology. IIUM Engineering Journal, 19 (1). pp. 34-47. ISSN 1511-788X https://doi.org/10.31436/iiumej.v19i1.814 doi: 10.31436/iiumej.v19i1.814
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	T Technology (General)
spellingShingle	T Technology (General) Nor Farhana, Hamid Farhan, Mohd Said Optimization of Red Pigment Production By Monascus Purpureus FTC 5356 Using Response Surface Methodology
description	Important factor such as certain environmental conditions and nutrients as a source for the medium are significant for successful growth and reproduction of microorganism. Manipulation of the factor is the most effective way to stimulate the growth of the microorganism in subsequent optimize the quality of the product. In this study, Central Composite Design (CCD) of Response Surface Methodology (RSM) was used to optimize the production of red pigment by Monascus purpureus FTC 5356 using oil palm frond (OPF) as a substrate in solid state fermentation (SSF). The data was analyzed using Design Expert Software. The optimum combination predicted via RSM was confirmed through experimental. The interaction between three variables ie; initial moisture content (%), initial pH value (pH), and peptone concentration (%) was studied and modeled. The statistical analysis of the results showed that in the range studied, optimal condition for red pigment production (47 AU/g) with the biomass (425.1 mg/g) was 55% initial moisture content, 3% of peptone concentration and pH 3 for initial pH value of the substrate. The results of RSM showed that the initial pH value had significant effect on red pigment production (P-value <0.05). The validation of these results was also conducted by carried out fermentation with predicted condition and it was found that there are 0.373% higher in values of experimental result compared to the predicted values.
format	Article
author	Nor Farhana, Hamid Farhan, Mohd Said
author_facet	Nor Farhana, Hamid Farhan, Mohd Said
author_sort	Nor Farhana, Hamid
title	Optimization of Red Pigment Production By Monascus Purpureus FTC 5356 Using Response Surface Methodology
title_short	Optimization of Red Pigment Production By Monascus Purpureus FTC 5356 Using Response Surface Methodology
title_full	Optimization of Red Pigment Production By Monascus Purpureus FTC 5356 Using Response Surface Methodology
title_fullStr	Optimization of Red Pigment Production By Monascus Purpureus FTC 5356 Using Response Surface Methodology
title_full_unstemmed	Optimization of Red Pigment Production By Monascus Purpureus FTC 5356 Using Response Surface Methodology
title_sort	optimization of red pigment production by monascus purpureus ftc 5356 using response surface methodology
publisher	IIUM, Malaysia
publishDate	2018
url	http://umpir.ump.edu.my/id/eprint/17901/ http://umpir.ump.edu.my/id/eprint/17901/ http://umpir.ump.edu.my/id/eprint/17901/ http://umpir.ump.edu.my/id/eprint/17901/1/Optimization%20of%20Red%20Pigment%20Production%20By%20Monascus-fkksa-2018.pdf
first_indexed	2023-09-18T22:25:01Z
last_indexed	2023-09-18T22:25:01Z
_version_	1777415908067639296

Optimization of Red Pigment Production By Monascus Purpureus FTC 5356 Using Response Surface Methodology

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