Effects of Boundary Proximity on Monodispersed Microbubbles in Ultrasonic Fields

Microbubbles have demonstrated the potential to redraw the boundaries of biomedical applications and revolutionize diagnostic and therapeutic applications. However, the ability to distinguish the acoustic response from a cluster of microbubbles in close proximity to the vessel endothelial cell from...

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Main Authors:	Fatimah, Dzaharudin, Ooi, A., Manasseh, R.
Format:	Article
Language:	English
Published:	Elsevier 2017
Subjects:	TJ Mechanical engineering and machinery
Online Access:	http://umpir.ump.edu.my/id/eprint/19100/ http://umpir.ump.edu.my/id/eprint/19100/ http://umpir.ump.edu.my/id/eprint/19100/ http://umpir.ump.edu.my/id/eprint/19100/1/fkm-2017-Dzaharudin-Effects%20of%20boundary%20proximity%20on%20monodispersed1.pdf

id	ump-19100
recordtype	eprints
spelling	ump-191002018-03-07T07:19:32Z http://umpir.ump.edu.my/id/eprint/19100/ Effects of Boundary Proximity on Monodispersed Microbubbles in Ultrasonic Fields Fatimah, Dzaharudin Ooi, A. Manasseh, R. TJ Mechanical engineering and machinery Microbubbles have demonstrated the potential to redraw the boundaries of biomedical applications and revolutionize diagnostic and therapeutic applications. However, the ability to distinguish the acoustic response from a cluster of microbubbles in close proximity to the vessel endothelial cell from those that are not is a challenge that needs to be addressed. To address this, the present paper modifies the Keller-Miksis model to include the effects of a boundary. The acoustic responses are analysed via techniques from dynamical systems theory such as Poincaré plots and bifurcation diagrams. It is found that the presence of a boundary causes an intermittent route to chaos while microbubbles far from the boundary result in a period-doubling route to chaos as the single control parameter pressure amplitude is varied. The route to chaos is altered via antimonotinicity with increasing bubble-wall distance. It has also been found that the effects of coupling are significant as it alters the chaotic threshold to occur at lower driving pressure amplitudes. The results also suggest that the increase in coupling effects between microbubbles near a boundary lowers the pressure amplitude required for chaos and lowers the natural frequency of the cluster. Elsevier 2017-09-05 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/19100/1/fkm-2017-Dzaharudin-Effects%20of%20boundary%20proximity%20on%20monodispersed1.pdf Fatimah, Dzaharudin and Ooi, A. and Manasseh, R. (2017) Effects of Boundary Proximity on Monodispersed Microbubbles in Ultrasonic Fields. Journal of Sound and Vibration, 410 (8). pp. 330-342. ISSN 0022-460X https://doi.org/10.1016/j.jsv.2017.08.047 doi: 10.1016/j.jsv.2017.08.047
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	TJ Mechanical engineering and machinery
spellingShingle	TJ Mechanical engineering and machinery Fatimah, Dzaharudin Ooi, A. Manasseh, R. Effects of Boundary Proximity on Monodispersed Microbubbles in Ultrasonic Fields
description	Microbubbles have demonstrated the potential to redraw the boundaries of biomedical applications and revolutionize diagnostic and therapeutic applications. However, the ability to distinguish the acoustic response from a cluster of microbubbles in close proximity to the vessel endothelial cell from those that are not is a challenge that needs to be addressed. To address this, the present paper modifies the Keller-Miksis model to include the effects of a boundary. The acoustic responses are analysed via techniques from dynamical systems theory such as Poincaré plots and bifurcation diagrams. It is found that the presence of a boundary causes an intermittent route to chaos while microbubbles far from the boundary result in a period-doubling route to chaos as the single control parameter pressure amplitude is varied. The route to chaos is altered via antimonotinicity with increasing bubble-wall distance. It has also been found that the effects of coupling are significant as it alters the chaotic threshold to occur at lower driving pressure amplitudes. The results also suggest that the increase in coupling effects between microbubbles near a boundary lowers the pressure amplitude required for chaos and lowers the natural frequency of the cluster.
format	Article
author	Fatimah, Dzaharudin Ooi, A. Manasseh, R.
author_facet	Fatimah, Dzaharudin Ooi, A. Manasseh, R.
author_sort	Fatimah, Dzaharudin
title	Effects of Boundary Proximity on Monodispersed Microbubbles in Ultrasonic Fields
title_short	Effects of Boundary Proximity on Monodispersed Microbubbles in Ultrasonic Fields
title_full	Effects of Boundary Proximity on Monodispersed Microbubbles in Ultrasonic Fields
title_fullStr	Effects of Boundary Proximity on Monodispersed Microbubbles in Ultrasonic Fields
title_full_unstemmed	Effects of Boundary Proximity on Monodispersed Microbubbles in Ultrasonic Fields
title_sort	effects of boundary proximity on monodispersed microbubbles in ultrasonic fields
publisher	Elsevier
publishDate	2017
url	http://umpir.ump.edu.my/id/eprint/19100/ http://umpir.ump.edu.my/id/eprint/19100/ http://umpir.ump.edu.my/id/eprint/19100/ http://umpir.ump.edu.my/id/eprint/19100/1/fkm-2017-Dzaharudin-Effects%20of%20boundary%20proximity%20on%20monodispersed1.pdf
first_indexed	2023-09-18T22:27:21Z
last_indexed	2023-09-18T22:27:21Z
_version_	1777416055720771584

Effects of Boundary Proximity on Monodispersed Microbubbles in Ultrasonic Fields

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