Efficient Synthesis of Novel Pyridine-Based Derivatives via Suzuki Cross-Coupling Reaction of Commercially Available 5-Bromo-2-methylpyridin-3-amine: Quantum Mechanical Investigations and Biological Activities
The present study describes palladium-catalyzed one pot Suzuki cross-coupling reaction to synthesize a series of novel pyridine derivatives 2a–2i, 4a–4i. In brief, Suzuki cross-coupling reaction of 5-bromo-2-methylpyridin-3-amine (1) directly or via N-[5-bromo-2-methylpyridine-3-yl]acetamide (3) wit...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI - Open Access Publishing
2017
|
| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/19768/ http://umpir.ump.edu.my/id/eprint/19768/ http://umpir.ump.edu.my/id/eprint/19768/ http://umpir.ump.edu.my/id/eprint/19768/1/fist-2017-nadeem-Efficient%20Synthesis%20of%20Novel%20Pyridine-Based.pdf |