Factorial Design for the Effect of Ultrasound-Assisted Extraction (UAE) of Labisia pumila sp. in 25-L Mobile Extractor

Labisia pumila sp. is one of the herbs that have been widely utilized among Malay women in Malaysia. Traditionally, it is used as postpartum medication, health tonic and for body strength. In this study, a 2 -level factorial experimental design was used to investigate th...

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Main Authors:	Nuri Adilah Nashrulmillah, Idris, Ahmad Ziad, Sulaiman, Azilah, Ajit
Format:	Article
Language:	English
Published:	AENSI Publishing 2017
Subjects:	TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/19925/ http://umpir.ump.edu.my/id/eprint/19925/ http://umpir.ump.edu.my/id/eprint/19925/1/fkksa-2017-naidris-Factorial%20design%20for%20the%20effect%20of%20Ultrasound-Assisted%20Extraction.pdf

id	ump-19925
recordtype	eprints
spelling	ump-199252018-01-09T01:10:55Z http://umpir.ump.edu.my/id/eprint/19925/ Factorial Design for the Effect of Ultrasound-Assisted Extraction (UAE) of Labisia pumila sp. in 25-L Mobile Extractor Nuri Adilah Nashrulmillah, Idris Ahmad Ziad, Sulaiman Azilah, Ajit TP Chemical technology Labisia pumila sp. is one of the herbs that have been widely utilized among Malay women in Malaysia. Traditionally, it is used as postpartum medication, health tonic and for body strength. In this study, a 2 -level factorial experimental design was used to investigate the contribution of the main effect for the extraction of gallic acid in Labisia pumila sp. during ultrasound-assisted extraction (UAE) processes. The factors that have been preliminary screened were material to solvent ratio (1:20 and 1:40), temperature (50-80⁰C), duty cycles (0-50%) and extraction time (4-8 hours) and validated statistically by analysis of variance (ANOVA). The extracts were analyzed by HPLC-DAD using a marker compound, gallic acid. This study was found that the duty cycle was the most influential factor and followed by the extraction time and temperature. All interactions between the studied factors were significant at 95% confidence level. Based on the results, the maximum yield of extraction was obtained with a temperature 80⁰C, extraction time of 8 hours, the material to solvent of 1:20 and duty cycle 50%. At these conditions, extraction yield value determined as 105.731 ± 8.633mg GAE/g dry weight. The experimental values under optimal condition were in a good consistent with the predicted values. Overall, the results obtained gives useful directions on how to improve recovery by proper selection of extraction condition. AENSI Publishing 2017 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/19925/1/fkksa-2017-naidris-Factorial%20design%20for%20the%20effect%20of%20Ultrasound-Assisted%20Extraction.pdf Nuri Adilah Nashrulmillah, Idris and Ahmad Ziad, Sulaiman and Azilah, Ajit (2017) Factorial Design for the Effect of Ultrasound-Assisted Extraction (UAE) of Labisia pumila sp. in 25-L Mobile Extractor. Australian Journal of Basic and Applied Sciences, 11 (3). pp. 98-103. ISSN 1991-8178 http://www.ajbasweb.com/old/ajbas/2017/Special%20issue%20ICCEIB/98-103.pdf
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	TP Chemical technology
spellingShingle	TP Chemical technology Nuri Adilah Nashrulmillah, Idris Ahmad Ziad, Sulaiman Azilah, Ajit Factorial Design for the Effect of Ultrasound-Assisted Extraction (UAE) of Labisia pumila sp. in 25-L Mobile Extractor
description	Labisia pumila sp. is one of the herbs that have been widely utilized among Malay women in Malaysia. Traditionally, it is used as postpartum medication, health tonic and for body strength. In this study, a 2 -level factorial experimental design was used to investigate the contribution of the main effect for the extraction of gallic acid in Labisia pumila sp. during ultrasound-assisted extraction (UAE) processes. The factors that have been preliminary screened were material to solvent ratio (1:20 and 1:40), temperature (50-80⁰C), duty cycles (0-50%) and extraction time (4-8 hours) and validated statistically by analysis of variance (ANOVA). The extracts were analyzed by HPLC-DAD using a marker compound, gallic acid. This study was found that the duty cycle was the most influential factor and followed by the extraction time and temperature. All interactions between the studied factors were significant at 95% confidence level. Based on the results, the maximum yield of extraction was obtained with a temperature 80⁰C, extraction time of 8 hours, the material to solvent of 1:20 and duty cycle 50%. At these conditions, extraction yield value determined as 105.731 ± 8.633mg GAE/g dry weight. The experimental values under optimal condition were in a good consistent with the predicted values. Overall, the results obtained gives useful directions on how to improve recovery by proper selection of extraction condition.
format	Article
author	Nuri Adilah Nashrulmillah, Idris Ahmad Ziad, Sulaiman Azilah, Ajit
author_facet	Nuri Adilah Nashrulmillah, Idris Ahmad Ziad, Sulaiman Azilah, Ajit
author_sort	Nuri Adilah Nashrulmillah, Idris
title	Factorial Design for the Effect of Ultrasound-Assisted Extraction (UAE) of Labisia pumila sp. in 25-L Mobile Extractor
title_short	Factorial Design for the Effect of Ultrasound-Assisted Extraction (UAE) of Labisia pumila sp. in 25-L Mobile Extractor
title_full	Factorial Design for the Effect of Ultrasound-Assisted Extraction (UAE) of Labisia pumila sp. in 25-L Mobile Extractor
title_fullStr	Factorial Design for the Effect of Ultrasound-Assisted Extraction (UAE) of Labisia pumila sp. in 25-L Mobile Extractor
title_full_unstemmed	Factorial Design for the Effect of Ultrasound-Assisted Extraction (UAE) of Labisia pumila sp. in 25-L Mobile Extractor
title_sort	factorial design for the effect of ultrasound-assisted extraction (uae) of labisia pumila sp. in 25-l mobile extractor
publisher	AENSI Publishing
publishDate	2017
url	http://umpir.ump.edu.my/id/eprint/19925/ http://umpir.ump.edu.my/id/eprint/19925/ http://umpir.ump.edu.my/id/eprint/19925/1/fkksa-2017-naidris-Factorial%20design%20for%20the%20effect%20of%20Ultrasound-Assisted%20Extraction.pdf
first_indexed	2023-09-18T22:28:33Z
last_indexed	2023-09-18T22:28:33Z
_version_	1777416130805104640

Factorial Design for the Effect of Ultrasound-Assisted Extraction (UAE) of Labisia pumila sp. in 25-L Mobile Extractor

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