Application of Fractional Factorial Design (FFD) for Screening of Significant Factor in Influencing Succinic acid Production from Biodiesel Based Glycerol Using Escherichia Coli

Application of Fractional Factorial Design (FFD) for Screening of Significant Factor in Influencing Succinic acid Production from Biodiesel Based Glycerol Using Escherichia Coli

The production of succinic acid from biodiesel based glycerol was carried out using Escherichia coli K12 MG1655 strain. The contribution of every parameter was evaluated and optimized using statistical modeling. A 2 6-1 fractional factorial design (FFD) was applied to screen the effect of substrate...

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Main Authors: Mimi Sakinah, A. M., Noor Suhana, Adzahar
Format: Conference or Workshop Item
Language:English
Published: 2011
Subjects:
TP Chemical technology
Online Access:http://umpir.ump.edu.my/id/eprint/2026/
http://umpir.ump.edu.my/id/eprint/2026/
http://umpir.ump.edu.my/id/eprint/2026/1/Application_of_Fractional_Factorial_Design_%28FFD%29_for_Screening_of_Significant.PDF
id ump-2026
recordtype eprints
spelling ump-20262018-01-17T06:35:08Z http://umpir.ump.edu.my/id/eprint/2026/ Application of Fractional Factorial Design (FFD) for Screening of Significant Factor in Influencing Succinic acid Production from Biodiesel Based Glycerol Using Escherichia Coli Mimi Sakinah, A. M. Noor Suhana, Adzahar TP Chemical technology The production of succinic acid from biodiesel based glycerol was carried out using Escherichia coli K12 MG1655 strain. The contribution of every parameter was evaluated and optimized using statistical modeling. A 2 6-1 fractional factorial design (FFD) was applied to screen the effect of substrate concentration, tryptone concentration, sodium carbonate concentration, inoculums density, pH and incubation period for Escherichia coli reaction on succinic acid production. The result of first order factorial design showed that glycerol concentration, tryptone concentration, incubation period and pH had significant positive effect (p>0.001) to the reaction. Meanwhile, inoculums density and Na2CO concentration exhibited insignificant effect in the reaction. In addition, interaction between inoculums density of substrate concentration and tryptone concentration, glycerol concentration and Na23CO concentration, tryptone concentration and pH, Na32CO concentration and incubation period and inoculums density with pH gave significant effects (p<0.001) to succinic acid production. 2011 Conference or Workshop Item PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/2026/1/Application_of_Fractional_Factorial_Design_%28FFD%29_for_Screening_of_Significant.PDF Mimi Sakinah, A. M. and Noor Suhana, Adzahar (2011) Application of Fractional Factorial Design (FFD) for Screening of Significant Factor in Influencing Succinic acid Production from Biodiesel Based Glycerol Using Escherichia Coli. In: 4th International Conference on Modeling, Simulation and Applied Optimization (ICMSAO) 2011, 19-21 April 2011 , Kuala Lumpur. pp. 1-5.. http://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=05775476
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
topic TP Chemical technology
spellingShingle TP Chemical technology
Mimi Sakinah, A. M.
Noor Suhana, Adzahar
Application of Fractional Factorial Design (FFD) for Screening of Significant Factor in Influencing Succinic acid Production from Biodiesel Based Glycerol Using Escherichia Coli
description The production of succinic acid from biodiesel based glycerol was carried out using Escherichia coli K12 MG1655 strain. The contribution of every parameter was evaluated and optimized using statistical modeling. A 2 6-1 fractional factorial design (FFD) was applied to screen the effect of substrate concentration, tryptone concentration, sodium carbonate concentration, inoculums density, pH and incubation period for Escherichia coli reaction on succinic acid production. The result of first order factorial design showed that glycerol concentration, tryptone concentration, incubation period and pH had significant positive effect (p>0.001) to the reaction. Meanwhile, inoculums density and Na2CO concentration exhibited insignificant effect in the reaction. In addition, interaction between inoculums density of substrate concentration and tryptone concentration, glycerol concentration and Na23CO concentration, tryptone concentration and pH, Na32CO concentration and incubation period and inoculums density with pH gave significant effects (p<0.001) to succinic acid production.
format Conference or Workshop Item
author Mimi Sakinah, A. M.
Noor Suhana, Adzahar
author_facet Mimi Sakinah, A. M.
Noor Suhana, Adzahar
author_sort Mimi Sakinah, A. M.
title Application of Fractional Factorial Design (FFD) for Screening of Significant Factor in Influencing Succinic acid Production from Biodiesel Based Glycerol Using Escherichia Coli
title_short Application of Fractional Factorial Design (FFD) for Screening of Significant Factor in Influencing Succinic acid Production from Biodiesel Based Glycerol Using Escherichia Coli
title_full Application of Fractional Factorial Design (FFD) for Screening of Significant Factor in Influencing Succinic acid Production from Biodiesel Based Glycerol Using Escherichia Coli
title_fullStr Application of Fractional Factorial Design (FFD) for Screening of Significant Factor in Influencing Succinic acid Production from Biodiesel Based Glycerol Using Escherichia Coli
title_full_unstemmed Application of Fractional Factorial Design (FFD) for Screening of Significant Factor in Influencing Succinic acid Production from Biodiesel Based Glycerol Using Escherichia Coli
title_sort application of fractional factorial design (ffd) for screening of significant factor in influencing succinic acid production from biodiesel based glycerol using escherichia coli
publishDate 2011
url http://umpir.ump.edu.my/id/eprint/2026/
http://umpir.ump.edu.my/id/eprint/2026/
http://umpir.ump.edu.my/id/eprint/2026/1/Application_of_Fractional_Factorial_Design_%28FFD%29_for_Screening_of_Significant.PDF
first_indexed 2023-09-18T21:55:30Z
last_indexed 2023-09-18T21:55:30Z
_version_ 1777414051319513088

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