Extraction of polyphenol from phyllanthus niruri

Phyllanthus niruri which is also known as Dukung Anak is a plant which contain miscellaneous bioactive components which provide the medical effects such as antioxidant, anti-cancer and treating Hepatitis-B. Extraction is a common method to obtain bioactive component from plant materials therefore th...

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Main Author:	Kee, Keing Lee
Format:	Undergraduates Project Papers
Language:	English English English English
Published:	2017
Subjects:	TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/23054/ http://umpir.ump.edu.my/id/eprint/23054/ http://umpir.ump.edu.my/id/eprint/23054/1/Extraction%20of%20polyphenol%20from%20phyllanthus%20niruri%20-%20Table%20of%20contents.pdf http://umpir.ump.edu.my/id/eprint/23054/2/Extraction%20of%20polyphenol%20from%20phyllanthus%20niruri%20-%20Abstract.pdf http://umpir.ump.edu.my/id/eprint/23054/3/Extraction%20of%20polyphenol%20from%20phyllanthus%20niruri%20-%20Chapter%201.pdf http://umpir.ump.edu.my/id/eprint/23054/4/Extraction%20of%20polyphenol%20from%20phyllanthus%20niruri%20-%20References.pdf

id	ump-23054
recordtype	eprints
spelling	ump-230542018-12-14T03:17:37Z http://umpir.ump.edu.my/id/eprint/23054/ Extraction of polyphenol from phyllanthus niruri Kee, Keing Lee TP Chemical technology Phyllanthus niruri which is also known as Dukung Anak is a plant which contain miscellaneous bioactive components which provide the medical effects such as antioxidant, anti-cancer and treating Hepatitis-B. Extraction is a common method to obtain bioactive component from plant materials therefore this research is to elucidate the effect of solvents types and investigate the performance of different type extraction method on P.Niruri. Ultrasonic assisted extraction and microwave assisted extraction methods were studied because there is no previous work found in literature. Analysis such as Total Phenolic Content, Total Flavonoids Content, Ultra-Performance Liquid Chromatography were carried out throughout the research. From the works, it is found that highest yield of phyllanthin with 4.56mg Phy/g DW was obtained with 20% aqueous Isopropanol whereas the quercetin with the highest yield, 10.14mg Que/g DW in 20% aqueous ethanol and the highest yield 15.44mg GAE/g DW of gallic acid was obtained by using water. Central Composite Design analysis shown that microware assisted extraction with 250W power, 3.62 minutes and 52.58% ethanol concentration obtain the optimum yield of polyphenol extraction of 83.70%. In conclusion, the yield of bioactive component is highly dependent on solvent polarity used in extraction and microwave extraction method provides a fast extraction without significantly compromising the extraction yield compare to ultrasonic assisted extraction. 2017-05 Undergraduates Project Papers NonPeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/23054/1/Extraction%20of%20polyphenol%20from%20phyllanthus%20niruri%20-%20Table%20of%20contents.pdf pdf en http://umpir.ump.edu.my/id/eprint/23054/2/Extraction%20of%20polyphenol%20from%20phyllanthus%20niruri%20-%20Abstract.pdf pdf en http://umpir.ump.edu.my/id/eprint/23054/3/Extraction%20of%20polyphenol%20from%20phyllanthus%20niruri%20-%20Chapter%201.pdf pdf en http://umpir.ump.edu.my/id/eprint/23054/4/Extraction%20of%20polyphenol%20from%20phyllanthus%20niruri%20-%20References.pdf Kee, Keing Lee (2017) Extraction of polyphenol from phyllanthus niruri. Faculty of Chemical & Natural Resources Engineering, Universiti Malaysia Pahang. http://iportal.ump.edu.my/lib/item?id=chamo:102925&theme=UMP2
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English English English English
topic	TP Chemical technology
spellingShingle	TP Chemical technology Kee, Keing Lee Extraction of polyphenol from phyllanthus niruri
description	Phyllanthus niruri which is also known as Dukung Anak is a plant which contain miscellaneous bioactive components which provide the medical effects such as antioxidant, anti-cancer and treating Hepatitis-B. Extraction is a common method to obtain bioactive component from plant materials therefore this research is to elucidate the effect of solvents types and investigate the performance of different type extraction method on P.Niruri. Ultrasonic assisted extraction and microwave assisted extraction methods were studied because there is no previous work found in literature. Analysis such as Total Phenolic Content, Total Flavonoids Content, Ultra-Performance Liquid Chromatography were carried out throughout the research. From the works, it is found that highest yield of phyllanthin with 4.56mg Phy/g DW was obtained with 20% aqueous Isopropanol whereas the quercetin with the highest yield, 10.14mg Que/g DW in 20% aqueous ethanol and the highest yield 15.44mg GAE/g DW of gallic acid was obtained by using water. Central Composite Design analysis shown that microware assisted extraction with 250W power, 3.62 minutes and 52.58% ethanol concentration obtain the optimum yield of polyphenol extraction of 83.70%. In conclusion, the yield of bioactive component is highly dependent on solvent polarity used in extraction and microwave extraction method provides a fast extraction without significantly compromising the extraction yield compare to ultrasonic assisted extraction.
format	Undergraduates Project Papers
author	Kee, Keing Lee
author_facet	Kee, Keing Lee
author_sort	Kee, Keing Lee
title	Extraction of polyphenol from phyllanthus niruri
title_short	Extraction of polyphenol from phyllanthus niruri
title_full	Extraction of polyphenol from phyllanthus niruri
title_fullStr	Extraction of polyphenol from phyllanthus niruri
title_full_unstemmed	Extraction of polyphenol from phyllanthus niruri
title_sort	extraction of polyphenol from phyllanthus niruri
publishDate	2017
url	http://umpir.ump.edu.my/id/eprint/23054/ http://umpir.ump.edu.my/id/eprint/23054/ http://umpir.ump.edu.my/id/eprint/23054/1/Extraction%20of%20polyphenol%20from%20phyllanthus%20niruri%20-%20Table%20of%20contents.pdf http://umpir.ump.edu.my/id/eprint/23054/2/Extraction%20of%20polyphenol%20from%20phyllanthus%20niruri%20-%20Abstract.pdf http://umpir.ump.edu.my/id/eprint/23054/3/Extraction%20of%20polyphenol%20from%20phyllanthus%20niruri%20-%20Chapter%201.pdf http://umpir.ump.edu.my/id/eprint/23054/4/Extraction%20of%20polyphenol%20from%20phyllanthus%20niruri%20-%20References.pdf
first_indexed	2023-09-18T22:34:23Z
last_indexed	2023-09-18T22:34:23Z
_version_	1777416498020614144

Extraction of polyphenol from phyllanthus niruri

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