Organic Additives for the Enhancement of Laminar Flow in a Brain‐Vessels‐Like Microchannel Assembly

Flow enhancement which traditionally applicable in reducing the pressure drop in the core of the turbulent flow in pipes, ducts and conduits has extended its impact into medical field. A minute amount of flexible long chain polymers has been proven to be effective in enhancing and improve the blood...

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Main Authors:	Ling, Fiona W. M., Heidarinik, Somaye, Abdulbari, Hayder A.
Format:	Article
Language:	English
Published:	Wiley 2019
Subjects:	TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/23756/ http://umpir.ump.edu.my/id/eprint/23756/ http://umpir.ump.edu.my/id/eprint/23756/ http://umpir.ump.edu.my/id/eprint/23756/1/Organic%20Additives%20for%20the%20Enhancement%20of%20Laminar%20Flow%20in%20a%20Brain1.pdf

id	ump-23756
recordtype	eprints
spelling	ump-237562019-11-18T04:27:46Z http://umpir.ump.edu.my/id/eprint/23756/ Organic Additives for the Enhancement of Laminar Flow in a Brain‐Vessels‐Like Microchannel Assembly Ling, Fiona W. M. Heidarinik, Somaye Abdulbari, Hayder A. TP Chemical technology Flow enhancement which traditionally applicable in reducing the pressure drop in the core of the turbulent flow in pipes, ducts and conduits has extended its impact into medical field. A minute amount of flexible long chain polymers has been proven to be effective in enhancing and improve the blood flow which is normally in laminar regime. However, most of the investigated drag reducing additives (DRA) are artificial and carries properties including toxic and non-biodegradable thus raise the concern to be utilized in health applications. In this present work, organic polymers were extracted from okra, aloe vera and hibiscus leaves were used as DRA to enhance the laminar flow in custom-made microchannel that simulating the human brain vessels. The experiment was conducted using open-loop microfluidic system. Pressure measurements were used to evaluate the flow enhancement performance as the function of percentage of flow increment (%FI) of mucilage additives at different concentrations (100 to 1000 ppm). The results showed that the increasing of the okra mucilage concentration increased the drag reduction performance and reached to the maximum at 1000 ppm of okra solution. Both aloe vera and hibiscus mucilage showed greater drag reduction efficacy at lower additives concentration (100ppm, 300ppm and 500ppm). 14.03% of maximum flow enhancement was achieved by using 100 ppm of aloe vera mucilage at the operating pressure of 400 mbar. The results showed the potential of these organic polymers as DRA to enhance the blood flow thus could be a milestone in medical applications. Wiley 2019 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/23756/1/Organic%20Additives%20for%20the%20Enhancement%20of%20Laminar%20Flow%20in%20a%20Brain1.pdf Ling, Fiona W. M. and Heidarinik, Somaye and Abdulbari, Hayder A. (2019) Organic Additives for the Enhancement of Laminar Flow in a Brain‐Vessels‐Like Microchannel Assembly. Chemical Engineering and Technology, 42 (9). pp. 1788-1796. ISSN 1521-4125 https://doi.org/10.1002/ceat.201800474 https://doi.org/10.1002/ceat.201800474
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	TP Chemical technology
spellingShingle	TP Chemical technology Ling, Fiona W. M. Heidarinik, Somaye Abdulbari, Hayder A. Organic Additives for the Enhancement of Laminar Flow in a Brain‐Vessels‐Like Microchannel Assembly
description	Flow enhancement which traditionally applicable in reducing the pressure drop in the core of the turbulent flow in pipes, ducts and conduits has extended its impact into medical field. A minute amount of flexible long chain polymers has been proven to be effective in enhancing and improve the blood flow which is normally in laminar regime. However, most of the investigated drag reducing additives (DRA) are artificial and carries properties including toxic and non-biodegradable thus raise the concern to be utilized in health applications. In this present work, organic polymers were extracted from okra, aloe vera and hibiscus leaves were used as DRA to enhance the laminar flow in custom-made microchannel that simulating the human brain vessels. The experiment was conducted using open-loop microfluidic system. Pressure measurements were used to evaluate the flow enhancement performance as the function of percentage of flow increment (%FI) of mucilage additives at different concentrations (100 to 1000 ppm). The results showed that the increasing of the okra mucilage concentration increased the drag reduction performance and reached to the maximum at 1000 ppm of okra solution. Both aloe vera and hibiscus mucilage showed greater drag reduction efficacy at lower additives concentration (100ppm, 300ppm and 500ppm). 14.03% of maximum flow enhancement was achieved by using 100 ppm of aloe vera mucilage at the operating pressure of 400 mbar. The results showed the potential of these organic polymers as DRA to enhance the blood flow thus could be a milestone in medical applications.
format	Article
author	Ling, Fiona W. M. Heidarinik, Somaye Abdulbari, Hayder A.
author_facet	Ling, Fiona W. M. Heidarinik, Somaye Abdulbari, Hayder A.
author_sort	Ling, Fiona W. M.
title	Organic Additives for the Enhancement of Laminar Flow in a Brain‐Vessels‐Like Microchannel Assembly
title_short	Organic Additives for the Enhancement of Laminar Flow in a Brain‐Vessels‐Like Microchannel Assembly
title_full	Organic Additives for the Enhancement of Laminar Flow in a Brain‐Vessels‐Like Microchannel Assembly
title_fullStr	Organic Additives for the Enhancement of Laminar Flow in a Brain‐Vessels‐Like Microchannel Assembly
title_full_unstemmed	Organic Additives for the Enhancement of Laminar Flow in a Brain‐Vessels‐Like Microchannel Assembly
title_sort	organic additives for the enhancement of laminar flow in a brain‐vessels‐like microchannel assembly
publisher	Wiley
publishDate	2019
url	http://umpir.ump.edu.my/id/eprint/23756/ http://umpir.ump.edu.my/id/eprint/23756/ http://umpir.ump.edu.my/id/eprint/23756/ http://umpir.ump.edu.my/id/eprint/23756/1/Organic%20Additives%20for%20the%20Enhancement%20of%20Laminar%20Flow%20in%20a%20Brain1.pdf
first_indexed	2023-09-18T22:35:43Z
last_indexed	2023-09-18T22:35:43Z
_version_	1777416581583732736

Organic Additives for the Enhancement of Laminar Flow in a Brain‐Vessels‐Like Microchannel Assembly

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