An Overview of Chitosan Nanofibers and their Applications in the Drug Delivery Process

Chitosan is a polycationic natural polymer which is abundant in nature. Chitosan has gained much attention as natural polymer in the biomedical field. The up to date drug delivery as well as the nanotechnology in controlled release of drugs from chitosan nanofibers are focused in this review. Electr...

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Main Authors:	Aljbour, Nawzat D., Beg, M. D. H., Jolius, Gimbun, Alam, A. K. M. Moshiul
Format:	Article
Language:	English
Published:	Bentham Science Publishers B.V. 2019
Subjects:	TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/25052/ http://umpir.ump.edu.my/id/eprint/25052/ http://umpir.ump.edu.my/id/eprint/25052/ http://umpir.ump.edu.my/id/eprint/25052/1/An%20Overview%20of%20Chitosan%20Nanofibers%20and%20their%20Applications1.pdf

id	ump-25052
recordtype	eprints
spelling	ump-250522019-06-13T06:18:58Z http://umpir.ump.edu.my/id/eprint/25052/ An Overview of Chitosan Nanofibers and their Applications in the Drug Delivery Process Aljbour, Nawzat D. Beg, M. D. H. Jolius, Gimbun Alam, A. K. M. Moshiul TP Chemical technology Chitosan is a polycationic natural polymer which is abundant in nature. Chitosan has gained much attention as natural polymer in the biomedical field. The up to date drug delivery as well as the nanotechnology in controlled release of drugs from chitosan nanofibers are focused in this review. Electrospinning is one of the most established and widely used techniques for preparing nanofibers. This method is versatile and efficient for the production of continuous nanofibers. The chitosan-based nanofibers are emerging materials in the arena of biomaterials. Recent studies revealed that various drugs such as antibiotics, chemotherapeutic agents, proteins and anti-inflammatory analgesic drugs were successfully loaded onto electrospun nanofibers. Chitosan nanofibers have several outstanding properties for different significant pharmaceutical applications such as wound dressing, tissue engineering, enzyme immobilization, and drug delivery systems. This review highlights different issues of chitosan nanofibers in drug delivery applications, starting from the preparation of chitosan nanofibers, followed by giving an idea about the biocompatibility and degradation of chitosan nanofibers, then describing how to load the drug into the nanofibers. Finally, the major applications of chitosan nanofibers in drug delivery systems. Bentham Science Publishers B.V. 2019-05-01 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/25052/1/An%20Overview%20of%20Chitosan%20Nanofibers%20and%20their%20Applications1.pdf Aljbour, Nawzat D. and Beg, M. D. H. and Jolius, Gimbun and Alam, A. K. M. Moshiul (2019) An Overview of Chitosan Nanofibers and their Applications in the Drug Delivery Process. Current Drug Delivery, 16 (4). pp. 272-294. ISSN 1875-5704 https://doi.org/10.2174/1567201816666190123121425 https://doi.org/10.2174/1567201816666190123121425
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	TP Chemical technology
spellingShingle	TP Chemical technology Aljbour, Nawzat D. Beg, M. D. H. Jolius, Gimbun Alam, A. K. M. Moshiul An Overview of Chitosan Nanofibers and their Applications in the Drug Delivery Process
description	Chitosan is a polycationic natural polymer which is abundant in nature. Chitosan has gained much attention as natural polymer in the biomedical field. The up to date drug delivery as well as the nanotechnology in controlled release of drugs from chitosan nanofibers are focused in this review. Electrospinning is one of the most established and widely used techniques for preparing nanofibers. This method is versatile and efficient for the production of continuous nanofibers. The chitosan-based nanofibers are emerging materials in the arena of biomaterials. Recent studies revealed that various drugs such as antibiotics, chemotherapeutic agents, proteins and anti-inflammatory analgesic drugs were successfully loaded onto electrospun nanofibers. Chitosan nanofibers have several outstanding properties for different significant pharmaceutical applications such as wound dressing, tissue engineering, enzyme immobilization, and drug delivery systems. This review highlights different issues of chitosan nanofibers in drug delivery applications, starting from the preparation of chitosan nanofibers, followed by giving an idea about the biocompatibility and degradation of chitosan nanofibers, then describing how to load the drug into the nanofibers. Finally, the major applications of chitosan nanofibers in drug delivery systems.
format	Article
author	Aljbour, Nawzat D. Beg, M. D. H. Jolius, Gimbun Alam, A. K. M. Moshiul
author_facet	Aljbour, Nawzat D. Beg, M. D. H. Jolius, Gimbun Alam, A. K. M. Moshiul
author_sort	Aljbour, Nawzat D.
title	An Overview of Chitosan Nanofibers and their Applications in the Drug Delivery Process
title_short	An Overview of Chitosan Nanofibers and their Applications in the Drug Delivery Process
title_full	An Overview of Chitosan Nanofibers and their Applications in the Drug Delivery Process
title_fullStr	An Overview of Chitosan Nanofibers and their Applications in the Drug Delivery Process
title_full_unstemmed	An Overview of Chitosan Nanofibers and their Applications in the Drug Delivery Process
title_sort	overview of chitosan nanofibers and their applications in the drug delivery process
publisher	Bentham Science Publishers B.V.
publishDate	2019
url	http://umpir.ump.edu.my/id/eprint/25052/ http://umpir.ump.edu.my/id/eprint/25052/ http://umpir.ump.edu.my/id/eprint/25052/ http://umpir.ump.edu.my/id/eprint/25052/1/An%20Overview%20of%20Chitosan%20Nanofibers%20and%20their%20Applications1.pdf
first_indexed	2023-09-18T22:38:16Z
last_indexed	2023-09-18T22:38:16Z
_version_	1777416741970771968

An Overview of Chitosan Nanofibers and their Applications in the Drug Delivery Process

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