Electrochemical detection of gliclazide and glibenclamide on ZnIn2S4 nanoparticles-modified carbon ionic liquid electrode

This research introduces a new modification of carbon paste electrode (CPE) by ZnIn2S4 nanoparticles (ZIS) and an ionic liquid (1-butyl-3-methylimidazolium hexafluorophosphate, (BMIM.PF6)) as a sensitive sensor for voltammetric detection of gliclazide and glibenclamide compared to unmodified carbon...

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Main Authors:	Pourtaheri, Ehsan, Taher, Mohammad Ali, Ali, Gomaa A. M., Gupta, Vinod Kumar
Format:	Article
Language:	English
Published:	Elsevier 2019
Subjects:	QD Chemistry TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/25376/ http://umpir.ump.edu.my/id/eprint/25376/ http://umpir.ump.edu.my/id/eprint/25376/ http://umpir.ump.edu.my/id/eprint/25376/1/Electrochemical%20detection%20of%20gliclazide%20and%20glibenclamide%20on%20ZnIn2S4%20.pdf

id	ump-25376
recordtype	eprints
spelling	ump-253762019-10-25T03:43:53Z http://umpir.ump.edu.my/id/eprint/25376/ Electrochemical detection of gliclazide and glibenclamide on ZnIn2S4 nanoparticles-modified carbon ionic liquid electrode Pourtaheri, Ehsan Taher, Mohammad Ali Ali, Gomaa A. M. Gupta, Vinod Kumar QD Chemistry TP Chemical technology This research introduces a new modification of carbon paste electrode (CPE) by ZnIn2S4 nanoparticles (ZIS) and an ionic liquid (1-butyl-3-methylimidazolium hexafluorophosphate, (BMIM.PF6)) as a sensitive sensor for voltammetric detection of gliclazide and glibenclamide compared to unmodified carbon paste electrode. The modified electrode (ZISILCPE) was characterized by different techniques such as cyclic voltammetry (CV), differential pulse voltammetry (DPV) and chronoamperometry (CHA). The electrochemical parameters of gliclazide were studied on the modified electrode surface. It was revealed that the performance of ZISILCPE sensor toward electrochemical detection of gliclazide and glibenclamide has significantly improved, in aqueous solution. The electrocatalytic features of the modified sensor were further exploited for the detection of gliclazide by DPV as a sensitive detection method. The sensor showed two well-expressed voltammetric peaks for two targets, and successfully resolved the overlap of corresponding voltammetric responses. Based on DPV, there was a linear increase for the peak currents from gliclazide and glibenclamide respectively with their concentrations ranging from 7.5 × 10−7–5.0 × 10−4 M to 1.0 × 10−6–8.0 × 10−4 M. According to the ZISILCPE, gliclazide and glibenclamide demonstrated the detection limits of 1.2 × 10−7 M and 8.0 × 10−7 M, respectively. The offered protocol was also efficient to detect two analytes in pharmaceuticals and urine samples. Elsevier 2019-09-01 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/25376/1/Electrochemical%20detection%20of%20gliclazide%20and%20glibenclamide%20on%20ZnIn2S4%20.pdf Pourtaheri, Ehsan and Taher, Mohammad Ali and Ali, Gomaa A. M. and Gupta, Vinod Kumar (2019) Electrochemical detection of gliclazide and glibenclamide on ZnIn2S4 nanoparticles-modified carbon ionic liquid electrode. Journal of Molecular Liquids, 289. pp. 1-2. ISSN 0167-7322 https://doi.org/10.1016/j.molliq.2019.111141 https://doi.org/10.1016/j.molliq.2019.111141
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	QD Chemistry TP Chemical technology
spellingShingle	QD Chemistry TP Chemical technology Pourtaheri, Ehsan Taher, Mohammad Ali Ali, Gomaa A. M. Gupta, Vinod Kumar Electrochemical detection of gliclazide and glibenclamide on ZnIn2S4 nanoparticles-modified carbon ionic liquid electrode
description	This research introduces a new modification of carbon paste electrode (CPE) by ZnIn2S4 nanoparticles (ZIS) and an ionic liquid (1-butyl-3-methylimidazolium hexafluorophosphate, (BMIM.PF6)) as a sensitive sensor for voltammetric detection of gliclazide and glibenclamide compared to unmodified carbon paste electrode. The modified electrode (ZISILCPE) was characterized by different techniques such as cyclic voltammetry (CV), differential pulse voltammetry (DPV) and chronoamperometry (CHA). The electrochemical parameters of gliclazide were studied on the modified electrode surface. It was revealed that the performance of ZISILCPE sensor toward electrochemical detection of gliclazide and glibenclamide has significantly improved, in aqueous solution. The electrocatalytic features of the modified sensor were further exploited for the detection of gliclazide by DPV as a sensitive detection method. The sensor showed two well-expressed voltammetric peaks for two targets, and successfully resolved the overlap of corresponding voltammetric responses. Based on DPV, there was a linear increase for the peak currents from gliclazide and glibenclamide respectively with their concentrations ranging from 7.5 × 10−7–5.0 × 10−4 M to 1.0 × 10−6–8.0 × 10−4 M. According to the ZISILCPE, gliclazide and glibenclamide demonstrated the detection limits of 1.2 × 10−7 M and 8.0 × 10−7 M, respectively. The offered protocol was also efficient to detect two analytes in pharmaceuticals and urine samples.
format	Article
author	Pourtaheri, Ehsan Taher, Mohammad Ali Ali, Gomaa A. M. Gupta, Vinod Kumar
author_facet	Pourtaheri, Ehsan Taher, Mohammad Ali Ali, Gomaa A. M. Gupta, Vinod Kumar
author_sort	Pourtaheri, Ehsan
title	Electrochemical detection of gliclazide and glibenclamide on ZnIn2S4 nanoparticles-modified carbon ionic liquid electrode
title_short	Electrochemical detection of gliclazide and glibenclamide on ZnIn2S4 nanoparticles-modified carbon ionic liquid electrode
title_full	Electrochemical detection of gliclazide and glibenclamide on ZnIn2S4 nanoparticles-modified carbon ionic liquid electrode
title_fullStr	Electrochemical detection of gliclazide and glibenclamide on ZnIn2S4 nanoparticles-modified carbon ionic liquid electrode
title_full_unstemmed	Electrochemical detection of gliclazide and glibenclamide on ZnIn2S4 nanoparticles-modified carbon ionic liquid electrode
title_sort	electrochemical detection of gliclazide and glibenclamide on znin2s4 nanoparticles-modified carbon ionic liquid electrode
publisher	Elsevier
publishDate	2019
url	http://umpir.ump.edu.my/id/eprint/25376/ http://umpir.ump.edu.my/id/eprint/25376/ http://umpir.ump.edu.my/id/eprint/25376/ http://umpir.ump.edu.my/id/eprint/25376/1/Electrochemical%20detection%20of%20gliclazide%20and%20glibenclamide%20on%20ZnIn2S4%20.pdf
first_indexed	2023-09-18T22:38:56Z
last_indexed	2023-09-18T22:38:56Z
_version_	1777416783683125248

Electrochemical detection of gliclazide and glibenclamide on ZnIn2S4 nanoparticles-modified carbon ionic liquid electrode

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