Antibacterial and antifungal activity of various extracts of Bacopa monnieri

Bacopa monnieri was also known as “Brahmi.” Theses plant has been considered as medicinal plants in Ayurvedic systems for centuries. This present study was carried out to evaluate the antibacterial and antifungal properties of ethanolic, diethyl ether, ethyl acetate, and aqueous extracts of B. monni...

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Main Authors:	M. K. K., Fazlul, S.P, Deepthi, Mohammed, Irfan, Farzana, Y., Munira, B., M.H.M, Nazmul
Format:	Article
Language:	English
Published:	Advanced Scientific Research 2019
Subjects:	T Technology (General) TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/25808/ http://umpir.ump.edu.my/id/eprint/25808/ http://umpir.ump.edu.my/id/eprint/25808/1/1706-1712%20fazlul.pdf

id	ump-25808
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spelling	ump-258082019-11-22T07:28:12Z http://umpir.ump.edu.my/id/eprint/25808/ Antibacterial and antifungal activity of various extracts of Bacopa monnieri M. K. K., Fazlul S.P, Deepthi Mohammed, Irfan Farzana, Y. Munira, B. M.H.M, Nazmul T Technology (General) TP Chemical technology Bacopa monnieri was also known as “Brahmi.” Theses plant has been considered as medicinal plants in Ayurvedic systems for centuries. This present study was carried out to evaluate the antibacterial and antifungal properties of ethanolic, diethyl ether, ethyl acetate, and aqueous extracts of B. monnieri. Agar disc diffusion tests were carried out to determine the antimicrobial effects of ethanolic, diethyl ether, ethyl acetate and aqueous extracts of B. monnieri against Gram-positive (Staphylococcus aureus ATCC 25923), Gram-negative (Escherichia coli ATCC 25922) bacterial strains and antifungal strains (Aspergillus flavus, and Candida albicans). Among the various extracts, diethyl ether extracts of B. monnieri has an antibacterial potency against Staphylococcus aureus (gram positive), and ethyl acetate extract showed effects on E. coli (gram negative) at higher concentrations of 300 µg mL-1. The ethanolic extract has potent antifungal activity against the fungus (Aspergillus flavus, and Candida albicans) compared to diethyl ether and ethyl acetate-ether. Both extracts (diethyl ether and ethyl acetate) has a minimum antifungal effect while these extracts showed more inhibitory effects on tested bacteria. Inhibitory effects of the aqueous extract were not observed at all concentration (100 µg mL-1, 200 µg mL-1and 300 µg mL-1) against the entire examined bacterial and fungal species. The finding of this study indicates the antibacterial and antifungal activity exhibited by the ethanolic, diethyl ether, and ethyl acetate extract of B. monnieri can be validated to the management of medicinal plant throughout the world. Advanced Scientific Research 2019-01 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/25808/1/1706-1712%20fazlul.pdf M. K. K., Fazlul and S.P, Deepthi and Mohammed, Irfan and Farzana, Y. and Munira, B. and M.H.M, Nazmul (2019) Antibacterial and antifungal activity of various extracts of Bacopa monnieri. International Journal of Pharmaceutical Research, 11 (1). pp. 1698-1702. ISSN 09752366 https://doi.org/10.31838/ijpr/2019.11.01.308
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	T Technology (General) TP Chemical technology
spellingShingle	T Technology (General) TP Chemical technology M. K. K., Fazlul S.P, Deepthi Mohammed, Irfan Farzana, Y. Munira, B. M.H.M, Nazmul Antibacterial and antifungal activity of various extracts of Bacopa monnieri
description	Bacopa monnieri was also known as “Brahmi.” Theses plant has been considered as medicinal plants in Ayurvedic systems for centuries. This present study was carried out to evaluate the antibacterial and antifungal properties of ethanolic, diethyl ether, ethyl acetate, and aqueous extracts of B. monnieri. Agar disc diffusion tests were carried out to determine the antimicrobial effects of ethanolic, diethyl ether, ethyl acetate and aqueous extracts of B. monnieri against Gram-positive (Staphylococcus aureus ATCC 25923), Gram-negative (Escherichia coli ATCC 25922) bacterial strains and antifungal strains (Aspergillus flavus, and Candida albicans). Among the various extracts, diethyl ether extracts of B. monnieri has an antibacterial potency against Staphylococcus aureus (gram positive), and ethyl acetate extract showed effects on E. coli (gram negative) at higher concentrations of 300 µg mL-1. The ethanolic extract has potent antifungal activity against the fungus (Aspergillus flavus, and Candida albicans) compared to diethyl ether and ethyl acetate-ether. Both extracts (diethyl ether and ethyl acetate) has a minimum antifungal effect while these extracts showed more inhibitory effects on tested bacteria. Inhibitory effects of the aqueous extract were not observed at all concentration (100 µg mL-1, 200 µg mL-1and 300 µg mL-1) against the entire examined bacterial and fungal species. The finding of this study indicates the antibacterial and antifungal activity exhibited by the ethanolic, diethyl ether, and ethyl acetate extract of B. monnieri can be validated to the management of medicinal plant throughout the world.
format	Article
author	M. K. K., Fazlul S.P, Deepthi Mohammed, Irfan Farzana, Y. Munira, B. M.H.M, Nazmul
author_facet	M. K. K., Fazlul S.P, Deepthi Mohammed, Irfan Farzana, Y. Munira, B. M.H.M, Nazmul
author_sort	M. K. K., Fazlul
title	Antibacterial and antifungal activity of various extracts of Bacopa monnieri
title_short	Antibacterial and antifungal activity of various extracts of Bacopa monnieri
title_full	Antibacterial and antifungal activity of various extracts of Bacopa monnieri
title_fullStr	Antibacterial and antifungal activity of various extracts of Bacopa monnieri
title_full_unstemmed	Antibacterial and antifungal activity of various extracts of Bacopa monnieri
title_sort	antibacterial and antifungal activity of various extracts of bacopa monnieri
publisher	Advanced Scientific Research
publishDate	2019
url	http://umpir.ump.edu.my/id/eprint/25808/ http://umpir.ump.edu.my/id/eprint/25808/ http://umpir.ump.edu.my/id/eprint/25808/1/1706-1712%20fazlul.pdf
first_indexed	2023-09-18T22:39:50Z
last_indexed	2023-09-18T22:39:50Z
_version_	1777416840997240832

Antibacterial and antifungal activity of various extracts of Bacopa monnieri

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