Finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion

One of the risks of ischaemic stroke reperfusion treatment is the formation of brain oedema. This is usually observed clinically by the formation of herniation, which if not treated, it may disrupt brain functionality. In this paper, a mathematical model of brain oedema formation after stroke has be...

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Main Authors: Mohd Jamil Mohamed, Mokhtarudin, Aina Najwa, Nadzri, Stephen, Payne
Format: Conference or Workshop Item
Language:English
Published: Universiti Malaysia Pahang 2019
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/26052/
http://umpir.ump.edu.my/id/eprint/26052/1/62.%20Finite%20element%20poroelastic%20modelling%20of%20brain%20oedema.pdf
id ump-26052
recordtype eprints
spelling ump-260522019-12-20T07:15:26Z http://umpir.ump.edu.my/id/eprint/26052/ Finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion Mohd Jamil Mohamed, Mokhtarudin Aina Najwa, Nadzri Stephen, Payne TJ Mechanical engineering and machinery One of the risks of ischaemic stroke reperfusion treatment is the formation of brain oedema. This is usually observed clinically by the formation of herniation, which if not treated, it may disrupt brain functionality. In this paper, a mathematical model of brain oedema formation after stroke has been developed and simulated on an ideal 3D brain geometry with different infarct sizes and locations, to see their effects on brain herniation. The brain tissue displacement and pressure are then analyzed. It is found that those infarcts with large sizes and located nearer to the brain ventricle cause severe brain herniation. Universiti Malaysia Pahang 2019 Conference or Workshop Item PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/26052/1/62.%20Finite%20element%20poroelastic%20modelling%20of%20brain%20oedema.pdf Mohd Jamil Mohamed, Mokhtarudin and Aina Najwa, Nadzri and Stephen, Payne (2019) Finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion. In: 6th International Conference on Computational and Mathematical Biomedical Engineering (CMBE 2019), 10-12 June 2019 , Japan. pp. 1-4..
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
topic TJ Mechanical engineering and machinery
spellingShingle TJ Mechanical engineering and machinery
Mohd Jamil Mohamed, Mokhtarudin
Aina Najwa, Nadzri
Stephen, Payne
Finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion
description One of the risks of ischaemic stroke reperfusion treatment is the formation of brain oedema. This is usually observed clinically by the formation of herniation, which if not treated, it may disrupt brain functionality. In this paper, a mathematical model of brain oedema formation after stroke has been developed and simulated on an ideal 3D brain geometry with different infarct sizes and locations, to see their effects on brain herniation. The brain tissue displacement and pressure are then analyzed. It is found that those infarcts with large sizes and located nearer to the brain ventricle cause severe brain herniation.
format Conference or Workshop Item
author Mohd Jamil Mohamed, Mokhtarudin
Aina Najwa, Nadzri
Stephen, Payne
author_facet Mohd Jamil Mohamed, Mokhtarudin
Aina Najwa, Nadzri
Stephen, Payne
author_sort Mohd Jamil Mohamed, Mokhtarudin
title Finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion
title_short Finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion
title_full Finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion
title_fullStr Finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion
title_full_unstemmed Finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion
title_sort finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion
publisher Universiti Malaysia Pahang
publishDate 2019
url http://umpir.ump.edu.my/id/eprint/26052/
http://umpir.ump.edu.my/id/eprint/26052/1/62.%20Finite%20element%20poroelastic%20modelling%20of%20brain%20oedema.pdf
first_indexed 2023-09-18T22:40:20Z
last_indexed 2023-09-18T22:40:20Z
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