Effect of factors on the red pigment production in the stirred drum bioreactor: fractional factorial design approach

Effect of factors on the red pigment production in the stirred drum bioreactor: fractional factorial design approach

Public demands on natural colouring over the synthetic colouring are growing due to consumer health concern towards the effect of synthetic colouring. The colorants production by employing fermentation process shows certain advantages. This research has emphasized on the capability of stirred drum b...

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Main Authors: Farhan, Mohd Said, Mohamad Al Aamin, Razali
Format: Conference or Workshop Item
Language:English
Published: AIP Publishing LLC. 2019
Subjects:
T Technology (General)
TP Chemical technology
Online Access:http://umpir.ump.edu.my/id/eprint/26259/
http://umpir.ump.edu.my/id/eprint/26259/
http://umpir.ump.edu.my/id/eprint/26259/
http://umpir.ump.edu.my/id/eprint/26259/1/1.5125512%20Aamin.pdf
id ump-26259
recordtype eprints
spelling ump-262592019-12-17T08:33:08Z http://umpir.ump.edu.my/id/eprint/26259/ Effect of factors on the red pigment production in the stirred drum bioreactor: fractional factorial design approach Farhan, Mohd Said Mohamad Al Aamin, Razali T Technology (General) TP Chemical technology Public demands on natural colouring over the synthetic colouring are growing due to consumer health concern towards the effect of synthetic colouring. The colorants production by employing fermentation process shows certain advantages. This research has emphasized on the capability of stirred drum bioreactor on performing red pigment in solid-state fermentation (SSF) of Monascus purpureus FTC 5357 by using oil palm frond (OPF). A Fractional factorial experimental design 24 (FFD) was applied in order to evaluate the effect of initial moisture content (IMC), inoculum size, percentage of peptone, pH, aeration rate, loading capacity and agitation programme on the red pigment production. In the FFD experimental studies, the highest pigment production was obtained at 75% (v/w) initial moisture content, 10^8 spores/mL of inoculum size, initial pH of 4, aeration rate of 1.21 vvm, loading capacity of 35% (v/v), agitation programme of 6 cycles/day, with the yield of 71.86 AU/g. The initial moisture content had the most pronounced affects to the red pigment production, followed by the aeration rate of stirred drum bioreactor, peptone concentration and inoculum size. The loading capacity of the bioreactor, agitation programme and the initial pH had the lesser effect to the red pigment production. The result indicated that FFD was a useful tool to improve the red pigment production in SSF using stirred drum bioreactor by considering all the factors involved. AIP Publishing LLC. 2019-09-06 Conference or Workshop Item PeerReviewed pdf en cc_by http://umpir.ump.edu.my/id/eprint/26259/1/1.5125512%20Aamin.pdf Farhan, Mohd Said and Mohamad Al Aamin, Razali (2019) Effect of factors on the red pigment production in the stirred drum bioreactor: fractional factorial design approach. In: AIP Conference Proceedings: Proceedings Of The 2nd International Conference On Biosciences And Medical Engineering (ICBME2019), 11-12 April 2019 , Bali, Indonesia. pp. 1-8., 2155 (020008). ISBN 978-073541900-1 https://doi.org/10.1063/1.5125512 https://doi.org/10.1063/1.5125512
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
topic T Technology (General)
TP Chemical technology
spellingShingle T Technology (General)
TP Chemical technology
Farhan, Mohd Said
Mohamad Al Aamin, Razali
Effect of factors on the red pigment production in the stirred drum bioreactor: fractional factorial design approach
description Public demands on natural colouring over the synthetic colouring are growing due to consumer health concern towards the effect of synthetic colouring. The colorants production by employing fermentation process shows certain advantages. This research has emphasized on the capability of stirred drum bioreactor on performing red pigment in solid-state fermentation (SSF) of Monascus purpureus FTC 5357 by using oil palm frond (OPF). A Fractional factorial experimental design 24 (FFD) was applied in order to evaluate the effect of initial moisture content (IMC), inoculum size, percentage of peptone, pH, aeration rate, loading capacity and agitation programme on the red pigment production. In the FFD experimental studies, the highest pigment production was obtained at 75% (v/w) initial moisture content, 10^8 spores/mL of inoculum size, initial pH of 4, aeration rate of 1.21 vvm, loading capacity of 35% (v/v), agitation programme of 6 cycles/day, with the yield of 71.86 AU/g. The initial moisture content had the most pronounced affects to the red pigment production, followed by the aeration rate of stirred drum bioreactor, peptone concentration and inoculum size. The loading capacity of the bioreactor, agitation programme and the initial pH had the lesser effect to the red pigment production. The result indicated that FFD was a useful tool to improve the red pigment production in SSF using stirred drum bioreactor by considering all the factors involved.
format Conference or Workshop Item
author Farhan, Mohd Said
Mohamad Al Aamin, Razali
author_facet Farhan, Mohd Said
Mohamad Al Aamin, Razali
author_sort Farhan, Mohd Said
title Effect of factors on the red pigment production in the stirred drum bioreactor: fractional factorial design approach
title_short Effect of factors on the red pigment production in the stirred drum bioreactor: fractional factorial design approach
title_full Effect of factors on the red pigment production in the stirred drum bioreactor: fractional factorial design approach
title_fullStr Effect of factors on the red pigment production in the stirred drum bioreactor: fractional factorial design approach
title_full_unstemmed Effect of factors on the red pigment production in the stirred drum bioreactor: fractional factorial design approach
title_sort effect of factors on the red pigment production in the stirred drum bioreactor: fractional factorial design approach
publisher AIP Publishing LLC.
publishDate 2019
url http://umpir.ump.edu.my/id/eprint/26259/
http://umpir.ump.edu.my/id/eprint/26259/
http://umpir.ump.edu.my/id/eprint/26259/
http://umpir.ump.edu.my/id/eprint/26259/1/1.5125512%20Aamin.pdf
first_indexed 2023-09-18T22:40:47Z
last_indexed 2023-09-18T22:40:47Z
_version_ 1777416900282679296

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