Preliminary phytochemical screening, GC-MS profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts

Preliminary phytochemical screening, GC-MS profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts

Therapeutic properties of the medicinal plant are due to the presence of phytochemical constituents. Garciniaatroviridis is locally known as ?asamgelugur? belongs to the Guttiferae family. Bioassay-guided solvent-solvent extraction method and yielded, hexane, dichloromethane, ethyl acetate, butanol,...

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Main Authors: Nur Salsabila, Ahmad Roslan, Zareen, Seema, Normaiza, Z., Akhtar, Muhammad Nadeem
Format: Article
Language:English
Published: IJAR 2018
Subjects:
QD Chemistry
Online Access:http://umpir.ump.edu.my/id/eprint/27170/
http://umpir.ump.edu.my/id/eprint/27170/
http://umpir.ump.edu.my/id/eprint/27170/
http://umpir.ump.edu.my/id/eprint/27170/1/827_IJAR-25789.pdf
id ump-27170
recordtype eprints
spelling ump-271702020-01-17T04:03:40Z http://umpir.ump.edu.my/id/eprint/27170/ Preliminary phytochemical screening, GC-MS profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts Nur Salsabila, Ahmad Roslan Zareen, Seema Normaiza, Z. Akhtar, Muhammad Nadeem QD Chemistry Therapeutic properties of the medicinal plant are due to the presence of phytochemical constituents. Garciniaatroviridis is locally known as ?asamgelugur? belongs to the Guttiferae family. Bioassay-guided solvent-solvent extraction method and yielded, hexane, dichloromethane, ethyl acetate, butanol, and methanolic extracts. These extracts were used to investigate the presence of phytochemicals. The preliminary phytochemical screening showed the existence of fixed oils and fats, carbohydrate, saponins, phenolic, flavonoids and anthraquinone glycosides in G. atroviridis roots. The chemical compositions were investigated by using Gas Chromatography-Mass Spectroscopy (GC-MS). Major compound identified in hexane, DCM, EA, BuOH and methanolic extracts was (Z)-13-docosenoic acid methyl ester (24.32%), ethyl-9-hexadecenoate (6.36%),bis(1,3-diisopropylcyclopentadienyl) (12.09%), 2-methyl-2-phenyl- 1,3-dioxolane (2.34%) and furfural (33.55%) respectively. The antibacterial and antioxidant activities of the extracts were investigated. The methanolic crude extract exhibited resistance towards both bacteria tested; Bacillus subtilisand Escherichia coli, thus suggesting its antibacterial activity. IJAR 2018 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/27170/1/827_IJAR-25789.pdf Nur Salsabila, Ahmad Roslan and Zareen, Seema and Normaiza, Z. and Akhtar, Muhammad Nadeem (2018) Preliminary phytochemical screening, GC-MS profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts. International Journal of Advanced Research, 7 (1). pp. 53-61. ISSN 2320-5407 https://doi.org/10.21474/IJAR01/8295 https://doi.org/10.21474/IJAR01/8295
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
topic QD Chemistry
spellingShingle QD Chemistry
Nur Salsabila, Ahmad Roslan
Zareen, Seema
Normaiza, Z.
Akhtar, Muhammad Nadeem
Preliminary phytochemical screening, GC-MS profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts
description Therapeutic properties of the medicinal plant are due to the presence of phytochemical constituents. Garciniaatroviridis is locally known as ?asamgelugur? belongs to the Guttiferae family. Bioassay-guided solvent-solvent extraction method and yielded, hexane, dichloromethane, ethyl acetate, butanol, and methanolic extracts. These extracts were used to investigate the presence of phytochemicals. The preliminary phytochemical screening showed the existence of fixed oils and fats, carbohydrate, saponins, phenolic, flavonoids and anthraquinone glycosides in G. atroviridis roots. The chemical compositions were investigated by using Gas Chromatography-Mass Spectroscopy (GC-MS). Major compound identified in hexane, DCM, EA, BuOH and methanolic extracts was (Z)-13-docosenoic acid methyl ester (24.32%), ethyl-9-hexadecenoate (6.36%),bis(1,3-diisopropylcyclopentadienyl) (12.09%), 2-methyl-2-phenyl- 1,3-dioxolane (2.34%) and furfural (33.55%) respectively. The antibacterial and antioxidant activities of the extracts were investigated. The methanolic crude extract exhibited resistance towards both bacteria tested; Bacillus subtilisand Escherichia coli, thus suggesting its antibacterial activity.
format Article
author Nur Salsabila, Ahmad Roslan
Zareen, Seema
Normaiza, Z.
Akhtar, Muhammad Nadeem
author_facet Nur Salsabila, Ahmad Roslan
Zareen, Seema
Normaiza, Z.
Akhtar, Muhammad Nadeem
author_sort Nur Salsabila, Ahmad Roslan
title Preliminary phytochemical screening, GC-MS profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts
title_short Preliminary phytochemical screening, GC-MS profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts
title_full Preliminary phytochemical screening, GC-MS profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts
title_fullStr Preliminary phytochemical screening, GC-MS profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts
title_full_unstemmed Preliminary phytochemical screening, GC-MS profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts
title_sort preliminary phytochemical screening, gc-ms profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts
publisher IJAR
publishDate 2018
url http://umpir.ump.edu.my/id/eprint/27170/
http://umpir.ump.edu.my/id/eprint/27170/
http://umpir.ump.edu.my/id/eprint/27170/
http://umpir.ump.edu.my/id/eprint/27170/1/827_IJAR-25789.pdf
first_indexed 2023-09-18T22:42:37Z
last_indexed 2023-09-18T22:42:37Z
_version_ 1777417016012963840

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