A case study - Regulation and Functional Mechanisms of Cancer Cells and Control its Activity Using Plants and their Derivatives

Novel exploiting to the understanding of conventional medicine was followed by the findings of many unique secondary metabolites and its biological property and is highly required for treating of many endemic diseases. The plants have been a long background in ethno pharmacological knowledge for tre...

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Main Authors:	Gaanty Pragas, Maniam, Kuppusamy, Palaniselvam, M. M., Yusoff, Natanamurugaraj, Govindan
Format:	Article
Language:	English
Published:	Elsevier 2013
Subjects:	Q Science (General) QD Chemistry
Online Access:	http://umpir.ump.edu.my/id/eprint/4081/ http://umpir.ump.edu.my/id/eprint/4081/ http://umpir.ump.edu.my/id/eprint/4081/ http://umpir.ump.edu.my/id/eprint/4081/1/A%20case%20study%20e%20Regulation%20and%20functional%20mechanisms%20of%20cancer%20cells%20and%20control%20its%20activity.pdf

id	ump-4081
recordtype	eprints
spelling	ump-40812017-12-27T04:30:14Z http://umpir.ump.edu.my/id/eprint/4081/ A case study - Regulation and Functional Mechanisms of Cancer Cells and Control its Activity Using Plants and their Derivatives Gaanty Pragas, Maniam Kuppusamy, Palaniselvam M. M., Yusoff Natanamurugaraj, Govindan Q Science (General) QD Chemistry Novel exploiting to the understanding of conventional medicine was followed by the findings of many unique secondary metabolites and its biological property and is highly required for treating of many endemic diseases. The plants have been a long background in ethno pharmacological knowledge for treatment of endemic and non-endemic diseases. Such plants are traditionally used in different form of paste, extraction and powder to treat seasonal diseases. Nowadays main uses of some medicinal plants have been a great deal with cure and control various chronic diseases such as cancer, AIDS, hepatitis, neurogenic disorders and acute kidney diseases. Cancer is molecular dysfunction and disarrangement in DNA base pairs it leads to change the human physiological and biochemical behavior of the system. Apoptotic mechanisms are regulating by two distinct pathways in which basic creeds perform in common to all eukaryotes. The key components in apoptosis especially mitochondrial intracellular organelles are identified (DNA, protein and ATP, Ca2+). These components control the next cellular binder step and participate in effecting cell suicide mechanisms. The diverse aspects of mitochondria involved in apoptosis include dealing with other proceedings such as release of protein or enzymes to effective for cell death. In these mechanism plants and related natural products using alternative therapeutic management, very less toxicity and cost benefits. Plant extracts and its biomass has revealed the existing of various pharmacologically active compounds like steroids, polyphenols, polysaccharides, saponins, alkaloids, tannins and terpenoids. The reliable natural products are acting as high sources for anticancer drugs. The natural derived compounds are the prolongation of life span of the zeolites and decrease of malignancy cell formation in the cellular system. Elsevier 2013-08-22 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/4081/1/A%20case%20study%20e%20Regulation%20and%20functional%20mechanisms%20of%20cancer%20cells%20and%20control%20its%20activity.pdf Gaanty Pragas, Maniam and Kuppusamy, Palaniselvam and M. M., Yusoff and Natanamurugaraj, Govindan (2013) A case study - Regulation and Functional Mechanisms of Cancer Cells and Control its Activity Using Plants and their Derivatives. Journal of Pharmacy Research , 6 (Issue ). pp. 884-892. ISSN 0974-6943 http://dx.doi.org/10.1016/j.jopr.2013.08.002 DOI: 10.1016/j.jopr.2013.08.002
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	Q Science (General) QD Chemistry
spellingShingle	Q Science (General) QD Chemistry Gaanty Pragas, Maniam Kuppusamy, Palaniselvam M. M., Yusoff Natanamurugaraj, Govindan A case study - Regulation and Functional Mechanisms of Cancer Cells and Control its Activity Using Plants and their Derivatives
description	Novel exploiting to the understanding of conventional medicine was followed by the findings of many unique secondary metabolites and its biological property and is highly required for treating of many endemic diseases. The plants have been a long background in ethno pharmacological knowledge for treatment of endemic and non-endemic diseases. Such plants are traditionally used in different form of paste, extraction and powder to treat seasonal diseases. Nowadays main uses of some medicinal plants have been a great deal with cure and control various chronic diseases such as cancer, AIDS, hepatitis, neurogenic disorders and acute kidney diseases. Cancer is molecular dysfunction and disarrangement in DNA base pairs it leads to change the human physiological and biochemical behavior of the system. Apoptotic mechanisms are regulating by two distinct pathways in which basic creeds perform in common to all eukaryotes. The key components in apoptosis especially mitochondrial intracellular organelles are identified (DNA, protein and ATP, Ca2+). These components control the next cellular binder step and participate in effecting cell suicide mechanisms. The diverse aspects of mitochondria involved in apoptosis include dealing with other proceedings such as release of protein or enzymes to effective for cell death. In these mechanism plants and related natural products using alternative therapeutic management, very less toxicity and cost benefits. Plant extracts and its biomass has revealed the existing of various pharmacologically active compounds like steroids, polyphenols, polysaccharides, saponins, alkaloids, tannins and terpenoids. The reliable natural products are acting as high sources for anticancer drugs. The natural derived compounds are the prolongation of life span of the zeolites and decrease of malignancy cell formation in the cellular system.
format	Article
author	Gaanty Pragas, Maniam Kuppusamy, Palaniselvam M. M., Yusoff Natanamurugaraj, Govindan
author_facet	Gaanty Pragas, Maniam Kuppusamy, Palaniselvam M. M., Yusoff Natanamurugaraj, Govindan
author_sort	Gaanty Pragas, Maniam
title	A case study - Regulation and Functional Mechanisms of Cancer Cells and Control its Activity Using Plants and their Derivatives
title_short	A case study - Regulation and Functional Mechanisms of Cancer Cells and Control its Activity Using Plants and their Derivatives
title_full	A case study - Regulation and Functional Mechanisms of Cancer Cells and Control its Activity Using Plants and their Derivatives
title_fullStr	A case study - Regulation and Functional Mechanisms of Cancer Cells and Control its Activity Using Plants and their Derivatives
title_full_unstemmed	A case study - Regulation and Functional Mechanisms of Cancer Cells and Control its Activity Using Plants and their Derivatives
title_sort	case study - regulation and functional mechanisms of cancer cells and control its activity using plants and their derivatives
publisher	Elsevier
publishDate	2013
url	http://umpir.ump.edu.my/id/eprint/4081/ http://umpir.ump.edu.my/id/eprint/4081/ http://umpir.ump.edu.my/id/eprint/4081/ http://umpir.ump.edu.my/id/eprint/4081/1/A%20case%20study%20e%20Regulation%20and%20functional%20mechanisms%20of%20cancer%20cells%20and%20control%20its%20activity.pdf
first_indexed	2023-09-18T21:58:35Z
last_indexed	2023-09-18T21:58:35Z
_version_	1777414245338578944

A case study - Regulation and Functional Mechanisms of Cancer Cells and Control its Activity Using Plants and their Derivatives

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