Total Synthesis, Cytotoxic Effects of Damnacanthal, Nordamnacanthal and Related Anthraquinone Analogues

Total Synthesis, Cytotoxic Effects of Damnacanthal, Nordamnacanthal and Related Anthraquinone Analogues

Naturally occurring anthraquinones, damnacanthal (1) and nordamnacanthal (2) were synthesized with modified reaction steps and investigated for their cytotoxicity against the MCF-7 and K-562 cancer cell lines, respectively. Intermediate analogues 2-bromomethyl-1,3-dimethoxyanthraquinone (5, IC50 = 5...

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Bibliographic Details
Main Authors:	Akhtar, Muhammad Nadeem, Seema, Zareen, Swee, Keong Yeap, Wan, Yong Ho, Kong, Mun Lo, Hasan, Aurangzeb, Noorjahan Banu, Alitheen
Format:	Article
Language:	English
Published:	MDPI - Open Access Publishing 2013
Subjects:	QD Chemistry
Online Access:	http://umpir.ump.edu.my/id/eprint/5262/ http://umpir.ump.edu.my/id/eprint/5262/ http://umpir.ump.edu.my/id/eprint/5262/ http://umpir.ump.edu.my/id/eprint/5262/1/FIST%2C_2013._Nadeem.pdf

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