Biosynthesized Gold Nanoparticle Developed as a Tool for Detection of HCG hormone in Pregnant Women Urine Sample

This paper presents a microencapsulation study using whey protein isolate and maltodextrin of polyphenol obtained from Orthosiphon stamineus leaves. Polyphenol content was analysed using ultra-performance liquid chromatography. Higher solid concentration leads to higher solution viscosity, bigger pa...

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Main Authors: Kuppusamy, Palaniselvam, M. M., Yusoff, Gaanty Pragas, Maniam, Natanamurugaraj, Govindan
Format: Article
Language:English
Published: Elsevier 2014
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/5314/
http://umpir.ump.edu.my/id/eprint/5314/
http://umpir.ump.edu.my/id/eprint/5314/
http://umpir.ump.edu.my/id/eprint/5314/1/fkksa-2014-kuppusamy-art.pdf
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spelling ump-53142018-07-27T01:35:20Z http://umpir.ump.edu.my/id/eprint/5314/ Biosynthesized Gold Nanoparticle Developed as a Tool for Detection of HCG hormone in Pregnant Women Urine Sample Kuppusamy, Palaniselvam M. M., Yusoff Gaanty Pragas, Maniam Natanamurugaraj, Govindan QR Microbiology This paper presents a microencapsulation study using whey protein isolate and maltodextrin of polyphenol obtained from Orthosiphon stamineus leaves. Polyphenol content was analysed using ultra-performance liquid chromatography. Higher solid concentration leads to higher solution viscosity, bigger particle size, lower moisture content and less dented surface, which may improve particle flowability. Microencapsulation using a least amount of protein (0.05wt.%) yielded better retention of romarinic acid (82.08%), sinensetin (79.57%) and eupatorin (81.08%) than those with higher protein concentration. Meanwhile, 5.33 wt.% of maltodextrin provide the highest polyphenol retention of rosmarinic acid (82.67%), sinensetin (82.24%) and eupatorin (80.19%). The results suggest that eupatorin and rosmarinic acid are more susceptible to thermal degradation than sinensetin during spray drying. Formulation using 5.33% maltodextrin provide a better preservation of polyphenols compared to other formulations. Elsevier 2014 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/5314/1/fkksa-2014-kuppusamy-art.pdf Kuppusamy, Palaniselvam and M. M., Yusoff and Gaanty Pragas, Maniam and Natanamurugaraj, Govindan (2014) Biosynthesized Gold Nanoparticle Developed as a Tool for Detection of HCG hormone in Pregnant Women Urine Sample. Asian Pacific Journal of Tropical Disease, 4 (3). p. 237. ISSN 2222-1808 http://dx.doi.org/10.1016/S2222-1808(14)60538-7 DOI: 10.1016/S2222-1808(14)60538-7
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
topic QR Microbiology
spellingShingle QR Microbiology
Kuppusamy, Palaniselvam
M. M., Yusoff
Gaanty Pragas, Maniam
Natanamurugaraj, Govindan
Biosynthesized Gold Nanoparticle Developed as a Tool for Detection of HCG hormone in Pregnant Women Urine Sample
description This paper presents a microencapsulation study using whey protein isolate and maltodextrin of polyphenol obtained from Orthosiphon stamineus leaves. Polyphenol content was analysed using ultra-performance liquid chromatography. Higher solid concentration leads to higher solution viscosity, bigger particle size, lower moisture content and less dented surface, which may improve particle flowability. Microencapsulation using a least amount of protein (0.05wt.%) yielded better retention of romarinic acid (82.08%), sinensetin (79.57%) and eupatorin (81.08%) than those with higher protein concentration. Meanwhile, 5.33 wt.% of maltodextrin provide the highest polyphenol retention of rosmarinic acid (82.67%), sinensetin (82.24%) and eupatorin (80.19%). The results suggest that eupatorin and rosmarinic acid are more susceptible to thermal degradation than sinensetin during spray drying. Formulation using 5.33% maltodextrin provide a better preservation of polyphenols compared to other formulations.
format Article
author Kuppusamy, Palaniselvam
M. M., Yusoff
Gaanty Pragas, Maniam
Natanamurugaraj, Govindan
author_facet Kuppusamy, Palaniselvam
M. M., Yusoff
Gaanty Pragas, Maniam
Natanamurugaraj, Govindan
author_sort Kuppusamy, Palaniselvam
title Biosynthesized Gold Nanoparticle Developed as a Tool for Detection of HCG hormone in Pregnant Women Urine Sample
title_short Biosynthesized Gold Nanoparticle Developed as a Tool for Detection of HCG hormone in Pregnant Women Urine Sample
title_full Biosynthesized Gold Nanoparticle Developed as a Tool for Detection of HCG hormone in Pregnant Women Urine Sample
title_fullStr Biosynthesized Gold Nanoparticle Developed as a Tool for Detection of HCG hormone in Pregnant Women Urine Sample
title_full_unstemmed Biosynthesized Gold Nanoparticle Developed as a Tool for Detection of HCG hormone in Pregnant Women Urine Sample
title_sort biosynthesized gold nanoparticle developed as a tool for detection of hcg hormone in pregnant women urine sample
publisher Elsevier
publishDate 2014
url http://umpir.ump.edu.my/id/eprint/5314/
http://umpir.ump.edu.my/id/eprint/5314/
http://umpir.ump.edu.my/id/eprint/5314/
http://umpir.ump.edu.my/id/eprint/5314/1/fkksa-2014-kuppusamy-art.pdf
first_indexed 2023-09-18T22:00:36Z
last_indexed 2023-09-18T22:00:36Z
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