Beyond Anticoagulant: Heparin as a Potential Anti-cancer Agent

Heparin has been in the market since the last six decades due to its potential anticoagulant property. The mechanism of its anti-coagulation effect is well established. Along with its anticoagulant activity the other activity that is gathering a lot of importance now-a-days is its ability to arrest...

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Main Authors:	Ravi, Lokwani, Nina Suhaity, Azmi, M. M., Yusoff, Solachuddin Jauhari, Arief Ichwan
Format:	Article
Language:	English
Published:	Hibiscus Publisher 2014
Subjects:	Q Science (General)
Online Access:	http://umpir.ump.edu.my/id/eprint/8820/ http://umpir.ump.edu.my/id/eprint/8820/ http://umpir.ump.edu.my/id/eprint/8820/1/Beyond%20Anticoagulant-%20Heparin%20as%20a%20Potential%20Anti-cancer%20Agent.pdf

id	ump-8820
recordtype	eprints
spelling	ump-88202018-01-22T01:16:29Z http://umpir.ump.edu.my/id/eprint/8820/ Beyond Anticoagulant: Heparin as a Potential Anti-cancer Agent Ravi, Lokwani Nina Suhaity, Azmi M. M., Yusoff Solachuddin Jauhari, Arief Ichwan Q Science (General) Heparin has been in the market since the last six decades due to its potential anticoagulant property. The mechanism of its anti-coagulation effect is well established. Along with its anticoagulant activity the other activity that is gathering a lot of importance now-a-days is its ability to arrest the progression of tumors specially some solid forms of tumors such as small cell lung carcinoma and pancreatic tumors. The chemically modified and light molecular weight fractions of heparin have been found to be more active in countering tumor progression. In this review we discuss a brief history of this versatile biomolecule with its clinical data and postulated mechanism of action as per recent studies. This review also highlighted the approach of heparin-conjugated nanoparticles to achieve targeted drug delivery with synergistic response in tumor cells. Hibiscus Publisher 2014 Article PeerReviewed application/pdf en cc_by http://umpir.ump.edu.my/id/eprint/8820/1/Beyond%20Anticoagulant-%20Heparin%20as%20a%20Potential%20Anti-cancer%20Agent.pdf Ravi, Lokwani and Nina Suhaity, Azmi and M. M., Yusoff and Solachuddin Jauhari, Arief Ichwan (2014) Beyond Anticoagulant: Heparin as a Potential Anti-cancer Agent. Journal Of Biochemistry, Microbiology and Biotechnology , 2 (2). pp. 37-43. ISSN 2289-5779 http://journal.hibiscuspublisher.com/index.php/JOBIMB/article/view/160
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	Q Science (General)
spellingShingle	Q Science (General) Ravi, Lokwani Nina Suhaity, Azmi M. M., Yusoff Solachuddin Jauhari, Arief Ichwan Beyond Anticoagulant: Heparin as a Potential Anti-cancer Agent
description	Heparin has been in the market since the last six decades due to its potential anticoagulant property. The mechanism of its anti-coagulation effect is well established. Along with its anticoagulant activity the other activity that is gathering a lot of importance now-a-days is its ability to arrest the progression of tumors specially some solid forms of tumors such as small cell lung carcinoma and pancreatic tumors. The chemically modified and light molecular weight fractions of heparin have been found to be more active in countering tumor progression. In this review we discuss a brief history of this versatile biomolecule with its clinical data and postulated mechanism of action as per recent studies. This review also highlighted the approach of heparin-conjugated nanoparticles to achieve targeted drug delivery with synergistic response in tumor cells.
format	Article
author	Ravi, Lokwani Nina Suhaity, Azmi M. M., Yusoff Solachuddin Jauhari, Arief Ichwan
author_facet	Ravi, Lokwani Nina Suhaity, Azmi M. M., Yusoff Solachuddin Jauhari, Arief Ichwan
author_sort	Ravi, Lokwani
title	Beyond Anticoagulant: Heparin as a Potential Anti-cancer Agent
title_short	Beyond Anticoagulant: Heparin as a Potential Anti-cancer Agent
title_full	Beyond Anticoagulant: Heparin as a Potential Anti-cancer Agent
title_fullStr	Beyond Anticoagulant: Heparin as a Potential Anti-cancer Agent
title_full_unstemmed	Beyond Anticoagulant: Heparin as a Potential Anti-cancer Agent
title_sort	beyond anticoagulant: heparin as a potential anti-cancer agent
publisher	Hibiscus Publisher
publishDate	2014
url	http://umpir.ump.edu.my/id/eprint/8820/ http://umpir.ump.edu.my/id/eprint/8820/ http://umpir.ump.edu.my/id/eprint/8820/1/Beyond%20Anticoagulant-%20Heparin%20as%20a%20Potential%20Anti-cancer%20Agent.pdf
first_indexed	2023-09-18T22:06:48Z
last_indexed	2023-09-18T22:06:48Z
_version_	1777414762595876864

Beyond Anticoagulant: Heparin as a Potential Anti-cancer Agent

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