Microwave-assisted synthesis of sec/tert-butyl 2-arylbenzimidazoles and their unexpected antiproliferative activity towards ER negative breast cancer cells
A new series of N-sec/tert-butyl 2-arylbenzimidazole derivatives was synthesised in 85–96% yields within 2–3.5 min by condensing ethyl 3-amino-4-butylamino benzoate with various substituted metabisulfite adducts of benzaldehyde under focused microwave irradiation. The benzimidazole analogues were ch...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Informa UK, Ltd.
2013
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/29457/ http://irep.iium.edu.my/29457/ http://irep.iium.edu.my/29457/ http://irep.iium.edu.my/29457/4/JEnxInhibition.pdf |