How accurate and precise are limited sampling strategies in estimating exposure to mycophenolic acid in people with autoimmune disease?

Mycophenolic acid (MPA) is a potent immunosuppressant agent, which is increasingly being used in the treatment of patients with various autoimmune diseases. Dosing to achieve a specific target MPA area under the concentration-time curve from 0 to 12 h post-dose (AUC12) is likely to lead to better tr...

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Bibliographic Details
Main Authors: Abd. Rahman, Nurul Azrin, Tett, Susan E., Staatz, Christine E.
Format: Article
Language:English
English
Published: Springer International Publishing AG 2014
Subjects:
Online Access:http://irep.iium.edu.my/40209/
http://irep.iium.edu.my/40209/1/Azrin.pdf
http://irep.iium.edu.my/40209/4/40209_How%20accurate%20and%20precise%20are%20limited.SCOPUSpdf.pdf