The MDM2 polymorphism SNP309 is associated with clinical characteristics and outcome in diffuse large B-cell lymphoma
Introduction The murine double minute 2 (MDM2) gene encodes a regulatory protein of the p53 pathway. A single nucleotide polymorphism (T to G change) at position 309 (SNP309) in the promotor region of MDM2 affects the transcription activity of MDM2 and has been found to be a negative prognostic mar...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English English |
Published: |
John Wiley & Sons Ltd
2014
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Subjects: | |
Online Access: | http://irep.iium.edu.my/43697/ http://irep.iium.edu.my/43697/ http://irep.iium.edu.my/43697/ http://irep.iium.edu.my/43697/4/Hedstrm_et_al-2014-European_Journal_of_Haematology_%281%29.pdf http://irep.iium.edu.my/43697/7/43697-The%20MDM2%20polymorphism%20SNP309_SCOPUS.pdf |