The MDM2 polymorphism SNP309 is associated with clinical characteristics and outcome in diffuse large B-cell lymphoma

Introduction The murine double minute 2 (MDM2) gene encodes a regulatory protein of the p53 pathway. A single nucleotide polymorphism (T to G change) at position 309 (SNP309) in the promotor region of MDM2 affects the transcription activity of MDM2 and has been found to be a negative prognostic mar...

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Bibliographic Details
Main Authors: Hedstrom, Gustav, Thunberg, Ulf, Amini, Rose-Marie, Zainuddin, Norafiza, Enblad, Gunilla, Berglund, Mattias
Format: Article
Language:English
English
Published: John Wiley & Sons Ltd 2014
Subjects:
Online Access:http://irep.iium.edu.my/43697/
http://irep.iium.edu.my/43697/
http://irep.iium.edu.my/43697/
http://irep.iium.edu.my/43697/4/Hedstrm_et_al-2014-European_Journal_of_Haematology_%281%29.pdf
http://irep.iium.edu.my/43697/7/43697-The%20MDM2%20polymorphism%20SNP309_SCOPUS.pdf