Human topoisomerase II alpha as a prognostic biomarker in cancer chemotherapy

Topoisomerases are nuclear enzymes that regulate topology of DNA by facilitating the temporary cleavage and ligation cycle of DNA. Among all forms of topoisomerases, TOP-IIA is extensively associated with cell proliferation and therefore is an important therapeutic target in diseases that involved c...

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Bibliographic Details
Main Authors: Ali, Yousaf, Abd Hamid, Shafida
Format: Article
Language:English
English
Published: Springer 2016
Subjects:
Online Access:http://irep.iium.edu.my/45324/
http://irep.iium.edu.my/45324/
http://irep.iium.edu.my/45324/
http://irep.iium.edu.my/45324/1/45324.pdf
http://irep.iium.edu.my/45324/4/45324_Human%20topoisomerase%20II%20alpha%20as%20a%20prognostic%20biomarker%20in%20cancer%20chemotherapy_SCOPUS.pdf