Potential novel inhibitors of trypanosomatid phosphoglycerate mutases through ligand-based and structure-based in silico approaches
Background & Hypothesis: The parasitic protozoa from the order Trypanosomatida relies exclusively on glycolysis for its survival in the mammalian hosts. As a corollary, the enzymes in this pathway have been recognised as chemotherapeutic targets. Phosphoglycerate mutase (iPGAM), which is the se...
| Main Authors: | , , , |
|---|---|
| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
Academy of Medicine, Singapore
2015
|
| Subjects: | |
| Online Access: | http://irep.iium.edu.my/45423/ http://irep.iium.edu.my/45423/ http://irep.iium.edu.my/45423/1/45423.pdf |