Quantitative evaluation of p16INK4a promoter methylation using pyrosequencing in de novo diffuse large B-cell lymphoma
The p16INK4a tumor suppressor gene can be inactivated by a variety of events including promoter hypermethylation. In diffuse large B-cell lymphoma (DLBCL), p16INK4a methylation has been associated with advanced disease stage and higher IPI. The prognostic impact of p16INK4a methylation in DLBCL rem...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Pergamon
2011
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/4588/ http://irep.iium.edu.my/4588/ http://irep.iium.edu.my/4588/ http://irep.iium.edu.my/4588/1/p16.pdf |