Baccaurea angulata fruit inhibits lipid peroxidation and induces the increase in antioxidant enzyme activities
Purpose: The consequence of the increased demand due to the population expansion has put tremendous pressure on the natural supply of fruits. Hence, there is an unprecedented growing interest in the exploration of the potentials of underutilized fruits as alternatives to the commercially available f...
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iium-507562017-10-09T07:45:39Z http://irep.iium.edu.my/50756/ Baccaurea angulata fruit inhibits lipid peroxidation and induces the increase in antioxidant enzyme activities Mikail, Maryam Abimbola Ahmed, Idris Adewale Ibrahim, Muhammad Hazali, Norazlanshan Abdull Rasad, Mohammad Syaiful Bahari Abdul Ghani, Radiah Hashim, Ridzwan Abdul Wahab, Ridhwan Arief Ichwan, Solachuddin Jauhari Md Isa, Muhammad Lokman Draman, Samsul Adros Yahya, Mohammad Noor R Medicine (General) Purpose: The consequence of the increased demand due to the population expansion has put tremendous pressure on the natural supply of fruits. Hence, there is an unprecedented growing interest in the exploration of the potentials of underutilized fruits as alternatives to the commercially available fruits. Baccaurea angulata is an underutilized fruit widely distributed in Borneo Island of Malaysia. The present study was conducted to investigate the effects of B. angulata whole fruit (WF), skin (SK) and pulp (PL) juices on malondialdehyde (MDA) levels and antioxidant enzymes in rabbits fed high-cholesterol diet.Methods: Thirty-six male rabbits of New Zealand strain were randomly assigned to six groups. Rabbits were fed either a standard pellet (group NC) or a high-cholesterol diet (groups HC, PC, WF, SK and PL). Groups WF, SK and PL were also given 1 ml/kg/day B. angulata WF, SK and PL juices, respectively. Results: Baccaurea angulata had high antioxidant activities. The administration of the various juices significantly reduced (p < 0.05) the concentration of induced plasma MDA. The decrease in the SOD, GPx, CAT and TAC levels caused by cholesterol feeding was also ameliorated with B. angulata. Conclusion: Our results show that B. angulata fruit is beneficial in positively influencing and managing oxidative damage. Springer 2016-06 Article PeerReviewed application/pdf en http://irep.iium.edu.my/50756/1/50756_Baccaurea_angulata_fruit_inhibits_lipid_peroxidation_and_induces_the_increase.pdf application/pdf en http://irep.iium.edu.my/50756/6/50756-Baccaurea%20angulata%20fruit%20inhibits%20lipid%20peroxidation%20and%20induces%20the%20increase_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/50756/7/50756-Baccaurea%20angulata%20fruit%20inhibits%20lipid%20peroxidation%20and%20induces%20the%20increase_WOS.pdf Mikail, Maryam Abimbola and Ahmed, Idris Adewale and Ibrahim, Muhammad and Hazali, Norazlanshan and Abdull Rasad, Mohammad Syaiful Bahari and Abdul Ghani, Radiah and Hashim, Ridzwan and Abdul Wahab, Ridhwan and Arief Ichwan, Solachuddin Jauhari and Md Isa, Muhammad Lokman and Draman, Samsul and Adros Yahya, Mohammad Noor (2016) Baccaurea angulata fruit inhibits lipid peroxidation and induces the increase in antioxidant enzyme activities. European Journal of Nutrition, 55 (4). pp. 1435-1444. ISSN 1436-6207 E-ISSN 1436-6215 http://link.springer.com/article/10.1007%2Fs00394-015-0961-7 10.1007/s00394-015-0961-7 |
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R Medicine (General) Mikail, Maryam Abimbola Ahmed, Idris Adewale Ibrahim, Muhammad Hazali, Norazlanshan Abdull Rasad, Mohammad Syaiful Bahari Abdul Ghani, Radiah Hashim, Ridzwan Abdul Wahab, Ridhwan Arief Ichwan, Solachuddin Jauhari Md Isa, Muhammad Lokman Draman, Samsul Adros Yahya, Mohammad Noor Baccaurea angulata fruit inhibits lipid peroxidation and induces the increase in antioxidant enzyme activities |
description |
Purpose: The consequence of the increased demand due to the population expansion has put tremendous pressure on the natural supply of fruits. Hence, there is an unprecedented growing interest in the exploration of the potentials of underutilized fruits as alternatives to the commercially available fruits. Baccaurea angulata is an underutilized fruit widely distributed in Borneo Island of Malaysia. The present study was conducted to investigate the effects of B. angulata whole fruit (WF), skin (SK) and pulp (PL) juices on malondialdehyde (MDA) levels and antioxidant enzymes in rabbits fed high-cholesterol diet.Methods: Thirty-six male rabbits of New Zealand strain were randomly assigned to six groups. Rabbits were fed either a standard pellet (group NC) or a high-cholesterol diet (groups HC, PC, WF, SK and PL). Groups WF, SK and PL were also given 1 ml/kg/day B. angulata WF, SK and PL juices, respectively. Results: Baccaurea angulata had high antioxidant activities. The administration of the various juices significantly reduced (p < 0.05) the concentration of induced plasma MDA. The decrease in the SOD, GPx, CAT and TAC levels caused by cholesterol feeding was also ameliorated with B. angulata. Conclusion: Our results show that B. angulata fruit is beneficial in positively influencing and managing oxidative damage. |
format |
Article |
author |
Mikail, Maryam Abimbola Ahmed, Idris Adewale Ibrahim, Muhammad Hazali, Norazlanshan Abdull Rasad, Mohammad Syaiful Bahari Abdul Ghani, Radiah Hashim, Ridzwan Abdul Wahab, Ridhwan Arief Ichwan, Solachuddin Jauhari Md Isa, Muhammad Lokman Draman, Samsul Adros Yahya, Mohammad Noor |
author_facet |
Mikail, Maryam Abimbola Ahmed, Idris Adewale Ibrahim, Muhammad Hazali, Norazlanshan Abdull Rasad, Mohammad Syaiful Bahari Abdul Ghani, Radiah Hashim, Ridzwan Abdul Wahab, Ridhwan Arief Ichwan, Solachuddin Jauhari Md Isa, Muhammad Lokman Draman, Samsul Adros Yahya, Mohammad Noor |
author_sort |
Mikail, Maryam Abimbola |
title |
Baccaurea angulata fruit inhibits lipid peroxidation and induces the increase in antioxidant enzyme activities |
title_short |
Baccaurea angulata fruit inhibits lipid peroxidation and induces the increase in antioxidant enzyme activities |
title_full |
Baccaurea angulata fruit inhibits lipid peroxidation and induces the increase in antioxidant enzyme activities |
title_fullStr |
Baccaurea angulata fruit inhibits lipid peroxidation and induces the increase in antioxidant enzyme activities |
title_full_unstemmed |
Baccaurea angulata fruit inhibits lipid peroxidation and induces the increase in antioxidant enzyme activities |
title_sort |
baccaurea angulata fruit inhibits lipid peroxidation and induces the increase in antioxidant enzyme activities |
publisher |
Springer |
publishDate |
2016 |
url |
http://irep.iium.edu.my/50756/ http://irep.iium.edu.my/50756/ http://irep.iium.edu.my/50756/ http://irep.iium.edu.my/50756/1/50756_Baccaurea_angulata_fruit_inhibits_lipid_peroxidation_and_induces_the_increase.pdf http://irep.iium.edu.my/50756/6/50756-Baccaurea%20angulata%20fruit%20inhibits%20lipid%20peroxidation%20and%20induces%20the%20increase_SCOPUS.pdf http://irep.iium.edu.my/50756/7/50756-Baccaurea%20angulata%20fruit%20inhibits%20lipid%20peroxidation%20and%20induces%20the%20increase_WOS.pdf |
first_indexed |
2023-09-18T21:11:48Z |
last_indexed |
2023-09-18T21:11:48Z |
_version_ |
1777411302040272896 |