Methylation-specific PCR Revealed Aberrant Promoter Gene Methylation of p16, MGMT and SPOCK2 in Diffuse Large B-cell Lymphoma
DNA methylation silences the gene through addition of methyl group. p16, a tumor suppressor gene that inhibits cyclin-dependent kinase, inactivates the Rb protein and blocks G1 phase in a normal cell cycle. A DNA repair gene, MGMT removes alkyl adduct to a cysteine residue within the protein...
| Main Authors: | , , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
2015
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/54383/ http://irep.iium.edu.my/54383/1/ICBHSR.pdf |