Methotrexate inhibits proliferation but not proteoglycan synthesis or glycosaminoglycan hyperelongation in human vascular smooth muscle cells

Objectives: Atherosclerosis is a disease process involving the early deposition of lipids in the vessel wall trapped by modified proteoglycans and subsequently a chronic inflammatory process leading to the clinical events. MTX has been chosen to study the potential efficacy of an anti inflammatory...

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Bibliographic Details
Main Authors: Little, Peter J., Getachew, Robel, Kamato, Danielle, Rostam, Muhamad Ashraf, Cohen, Neale, Chan, Vincent, Osman, Narin
Format: Article
Language:English
Published: OMICS International 2015
Subjects:
Online Access:http://irep.iium.edu.my/55384/
http://irep.iium.edu.my/55384/
http://irep.iium.edu.my/55384/
http://irep.iium.edu.my/55384/1/9.%20Little%202015%20methotrexate-.pdf