Synthesis, antiphospholipase A2, antiprotease, antibacterial evaluation and molecular docking analysis of certain novel hydrazones

Some novel hydrazone derivatives 6a-o were synthesized from the key intermediate 4-Chloro-N-(2-hydrazinocarbonyl-phenyl)-benzamide 5 and characterized using IR, 1H-NMR, 13C-NMR, mass spectroscopy and elemental analysis. The inhibitory potential against two secretory phospholipase A2 (sPLA2), three p...

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Bibliographic Details
Main Authors: El-Sayed, Nahed Nasser Eid, Alafeefy, Ahmed Mahmoud, Bakht, Mohammed Afroz, Vijay H., Masand, Aldalbahi, Ali, N., Chen, C., Fan, Bacha, Abir Ben Ben
Format: Article
Language:English
English
Published: MDPI AG 2016
Subjects:
Online Access:http://irep.iium.edu.my/56527/
http://irep.iium.edu.my/56527/
http://irep.iium.edu.my/56527/
http://irep.iium.edu.my/56527/1/56527_Synthesis%2C%20antiphospholipase%20A2%2C%20antiprotease.pdf
http://irep.iium.edu.my/56527/2/56527_Synthesis%2C%20antiphospholipase%20A2%2C%20antiprotease_Scopus.pdf