Mutation of arginine residues to avoid non-specific cellular uptakes for hepatitis B virus core particles

Mutation of arginine residues to avoid non-specific cellular uptakes for hepatitis B virus core particles

BACKGROUND: The hepatitis B virus core (HBc) particle is known as a promising new carrier for the delivery of drugs and nucleic acids. However, since the arginine-rich domain that is located in the C-terminal region of the HBc monomer binds to the heparan sulphate proteoglycan on the cell surface du...

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Bibliographic Details
Main Authors: Mohamed Suffian, Izzat Fahimuddin, Nishimura, Yuya, Morita, Kenta, Nakamura-Tsuruta, Sachiko, Al-Jamal, Khuloud, Ishii, Jun, Ogino, Chiaki, Kondo, Akihiko
Format: Article
Language:English
Published: Biomed Central 2015
Subjects:
QH301 Biology
QR355 Virology
RM Therapeutics. Pharmacology
Online Access:http://irep.iium.edu.my/57364/
http://irep.iium.edu.my/57364/
http://irep.iium.edu.my/57364/1/Suffian%20et%20al.%20Journal%20of%20Nanobiotechnology.pdf

Internet

http://irep.iium.edu.my/57364/
http://irep.iium.edu.my/57364/
http://irep.iium.edu.my/57364/1/Suffian%20et%20al.%20Journal%20of%20Nanobiotechnology.pdf

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