Microencapsulation of fish oil using supercritical antisolvent process

In order to improve the encapsulation process, a newly supercritical antisolvent process was developed to encapsulate fish oil using hydroxypropyl methyl cellulose as a polymer. Three factors, namely, temperature, pressure, and feed emulsion rate were optimized using response surface methodology. Th...

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Main Authors: Karim, Fahim Tamzeedul, Gahfoor, Kashif, Ferdosh, Sahena, Al-Juhaimi, Fahad, Ali, Eaqub, Yunus, Kamaruzzaman, Hamed, Mir Hoseini, Islam, Ashraful, Asif, Mohammad, Sarker, Md. Zaidul Islam
Format: Article
Language:English
English
English
Published: Elsevier Taiwan LLC 2017
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Online Access:http://irep.iium.edu.my/58010/
http://irep.iium.edu.my/58010/
http://irep.iium.edu.my/58010/
http://irep.iium.edu.my/58010/1/Microencapsulation%20of%20fish%20oil%20using%20supercritical.pdf
http://irep.iium.edu.my/58010/7/58010_Microencapsulation%20of%20fish%20oil_WOS.pdf
http://irep.iium.edu.my/58010/8/58010_Microencapsulation%20of%20fish%20oil_SCOPUS.pdf
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spelling iium-580102017-08-17T04:16:53Z http://irep.iium.edu.my/58010/ Microencapsulation of fish oil using supercritical antisolvent process Karim, Fahim Tamzeedul Gahfoor, Kashif Ferdosh, Sahena Al-Juhaimi, Fahad Ali, Eaqub Yunus, Kamaruzzaman Hamed, Mir Hoseini Islam, Ashraful Asif, Mohammad Sarker, Md. Zaidul Islam QD Chemistry In order to improve the encapsulation process, a newly supercritical antisolvent process was developed to encapsulate fish oil using hydroxypropyl methyl cellulose as a polymer. Three factors, namely, temperature, pressure, and feed emulsion rate were optimized using response surface methodology. The suitability of the model for predicting the optimum response value was evaluated at the conditions of temperature at 60�C, pressure at 150 bar, and feed rate at 1.36 mL/min. At the optimum conditions, particle size of 58.35 mm was obtained. The surface morphology of the micronized fish oil was also evaluated using field emission scanning electron microscopy where it showed that particles formed spherical structures with no internal voids. Moreover, in vitro release of oil showed that there are significant differences of release percentage of oil between the formulations and the results proved that there was a significant decrease in the in vitro release of oil from the powder when the polymer concentration was high. Elsevier Taiwan LLC 2017-07 Article PeerReviewed application/pdf en http://irep.iium.edu.my/58010/1/Microencapsulation%20of%20fish%20oil%20using%20supercritical.pdf application/pdf en http://irep.iium.edu.my/58010/7/58010_Microencapsulation%20of%20fish%20oil_WOS.pdf application/pdf en http://irep.iium.edu.my/58010/8/58010_Microencapsulation%20of%20fish%20oil_SCOPUS.pdf Karim, Fahim Tamzeedul and Gahfoor, Kashif and Ferdosh, Sahena and Al-Juhaimi, Fahad and Ali, Eaqub and Yunus, Kamaruzzaman and Hamed, Mir Hoseini and Islam, Ashraful and Asif, Mohammad and Sarker, Md. Zaidul Islam (2017) Microencapsulation of fish oil using supercritical antisolvent process. Journal of food and drug analysis, 25 (3). 654 -666. ISSN 1021-9498 http://www.sciencedirect.com/science/article/pii/S1021949817300297 10.1016/j.jfda.2016.11.017
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
English
topic QD Chemistry
spellingShingle QD Chemistry
Karim, Fahim Tamzeedul
Gahfoor, Kashif
Ferdosh, Sahena
Al-Juhaimi, Fahad
Ali, Eaqub
Yunus, Kamaruzzaman
Hamed, Mir Hoseini
Islam, Ashraful
Asif, Mohammad
Sarker, Md. Zaidul Islam
Microencapsulation of fish oil using supercritical antisolvent process
description In order to improve the encapsulation process, a newly supercritical antisolvent process was developed to encapsulate fish oil using hydroxypropyl methyl cellulose as a polymer. Three factors, namely, temperature, pressure, and feed emulsion rate were optimized using response surface methodology. The suitability of the model for predicting the optimum response value was evaluated at the conditions of temperature at 60�C, pressure at 150 bar, and feed rate at 1.36 mL/min. At the optimum conditions, particle size of 58.35 mm was obtained. The surface morphology of the micronized fish oil was also evaluated using field emission scanning electron microscopy where it showed that particles formed spherical structures with no internal voids. Moreover, in vitro release of oil showed that there are significant differences of release percentage of oil between the formulations and the results proved that there was a significant decrease in the in vitro release of oil from the powder when the polymer concentration was high.
format Article
author Karim, Fahim Tamzeedul
Gahfoor, Kashif
Ferdosh, Sahena
Al-Juhaimi, Fahad
Ali, Eaqub
Yunus, Kamaruzzaman
Hamed, Mir Hoseini
Islam, Ashraful
Asif, Mohammad
Sarker, Md. Zaidul Islam
author_facet Karim, Fahim Tamzeedul
Gahfoor, Kashif
Ferdosh, Sahena
Al-Juhaimi, Fahad
Ali, Eaqub
Yunus, Kamaruzzaman
Hamed, Mir Hoseini
Islam, Ashraful
Asif, Mohammad
Sarker, Md. Zaidul Islam
author_sort Karim, Fahim Tamzeedul
title Microencapsulation of fish oil using supercritical antisolvent process
title_short Microencapsulation of fish oil using supercritical antisolvent process
title_full Microencapsulation of fish oil using supercritical antisolvent process
title_fullStr Microencapsulation of fish oil using supercritical antisolvent process
title_full_unstemmed Microencapsulation of fish oil using supercritical antisolvent process
title_sort microencapsulation of fish oil using supercritical antisolvent process
publisher Elsevier Taiwan LLC
publishDate 2017
url http://irep.iium.edu.my/58010/
http://irep.iium.edu.my/58010/
http://irep.iium.edu.my/58010/
http://irep.iium.edu.my/58010/1/Microencapsulation%20of%20fish%20oil%20using%20supercritical.pdf
http://irep.iium.edu.my/58010/7/58010_Microencapsulation%20of%20fish%20oil_WOS.pdf
http://irep.iium.edu.my/58010/8/58010_Microencapsulation%20of%20fish%20oil_SCOPUS.pdf
first_indexed 2023-09-18T21:22:00Z
last_indexed 2023-09-18T21:22:00Z
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