Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia

Introduction: Abdominal obesity and inflammation are two independent risk factors for cardiovascular disease. However, the inter-relationship between these two factors among Malay population is fragmented. The purpose of this study is to determine the association between waist circumference as a mea...

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Main Authors: Shahadan, Siti Zuhaidah, Daud, Azlina, Md. Isa, Muhammad Lokman, Mohd Rasani, Ali Aminuddin, Ibrahim, Muhammad, Draman, Samsul
Format: Article
Language:English
English
English
Published: Kulliyyah (Faculty) of Medicine, International Islamic University Malaysia 2018
Subjects:
Online Access:http://irep.iium.edu.my/58135/
http://irep.iium.edu.my/58135/
http://irep.iium.edu.my/58135/19/58135%20Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive.pdf
http://irep.iium.edu.my/58135/13/58135_Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive%20Protein%20Level_SCOPUS.pdf
http://irep.iium.edu.my/58135/25/58135_Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive%20Protein%20Level%20among%20Malay%20Obese%20Adults%20in%20Kuantan%2C%20Malaysia_WOS.pdf
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spelling iium-581352019-01-24T01:42:07Z http://irep.iium.edu.my/58135/ Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia Shahadan, Siti Zuhaidah Daud, Azlina Md. Isa, Muhammad Lokman Mohd Rasani, Ali Aminuddin Ibrahim, Muhammad Draman, Samsul RT Nursing Introduction: Abdominal obesity and inflammation are two independent risk factors for cardiovascular disease. However, the inter-relationship between these two factors among Malay population is fragmented. The purpose of this study is to determine the association between waist circumference as a measure of abdominal obesity and high-sensitivity C-reactive protein as an indicator of inflammation status among Malay obese adults in Kuantan, Pahang. Materials and Methods: Ninety-three apparently healthy obese adults (BMI between 27.5 and 39.9 kg/m2) aged between 20 to 62 years old were recruited in this study (68% men and 32% women). Circumference tape was used to measure the waist circumference and fasting venous blood was obtained to determine the high-sensitivity C-reactive protein level. Results: On average, the waist circumference of obese men and women was 103 cm (SD = 8.7) and 94 cm (SD = 7.0), respectively. The median (IQR) of the hs-CRP level of the study participant was 3.80 mg/L (1.5, 10.1). The Kendall’s Tau correlation reveals that there is a significant positive linear correlation between waist circumference and hs-CRP level in obese men (r (30) = 0.355, p = 0.006) and women (r (63) = 0.177, p = 0.043). Conclusion: There is a significant inter-relationship between waist circumference and hs-CRP level among apparently healthy obese adults in Kuantan, Pahang. This study suggests that assessment of hs-CRP level is beneficial to predict the risk for future cardiovascular disease event and facilitate the management of obesity in this population. A prospective clinical study is recommended to confirm the findings. Kulliyyah (Faculty) of Medicine, International Islamic University Malaysia 2018-04 Article PeerReviewed application/pdf en http://irep.iium.edu.my/58135/19/58135%20Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive.pdf application/pdf en http://irep.iium.edu.my/58135/13/58135_Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive%20Protein%20Level_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/58135/25/58135_Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive%20Protein%20Level%20among%20Malay%20Obese%20Adults%20in%20Kuantan%2C%20Malaysia_WOS.pdf Shahadan, Siti Zuhaidah and Daud, Azlina and Md. Isa, Muhammad Lokman and Mohd Rasani, Ali Aminuddin and Ibrahim, Muhammad and Draman, Samsul (2018) Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia. International Medical Journal Malaysia, 17 (1). pp. 79-86. E-ISSN 1823-4631 http://iiumedic.net/imjm/v1/download/volume_17_no_1/Vol17-No1-p079086.pdf
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
English
topic RT Nursing
spellingShingle RT Nursing
Shahadan, Siti Zuhaidah
Daud, Azlina
Md. Isa, Muhammad Lokman
Mohd Rasani, Ali Aminuddin
Ibrahim, Muhammad
Draman, Samsul
Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia
description Introduction: Abdominal obesity and inflammation are two independent risk factors for cardiovascular disease. However, the inter-relationship between these two factors among Malay population is fragmented. The purpose of this study is to determine the association between waist circumference as a measure of abdominal obesity and high-sensitivity C-reactive protein as an indicator of inflammation status among Malay obese adults in Kuantan, Pahang. Materials and Methods: Ninety-three apparently healthy obese adults (BMI between 27.5 and 39.9 kg/m2) aged between 20 to 62 years old were recruited in this study (68% men and 32% women). Circumference tape was used to measure the waist circumference and fasting venous blood was obtained to determine the high-sensitivity C-reactive protein level. Results: On average, the waist circumference of obese men and women was 103 cm (SD = 8.7) and 94 cm (SD = 7.0), respectively. The median (IQR) of the hs-CRP level of the study participant was 3.80 mg/L (1.5, 10.1). The Kendall’s Tau correlation reveals that there is a significant positive linear correlation between waist circumference and hs-CRP level in obese men (r (30) = 0.355, p = 0.006) and women (r (63) = 0.177, p = 0.043). Conclusion: There is a significant inter-relationship between waist circumference and hs-CRP level among apparently healthy obese adults in Kuantan, Pahang. This study suggests that assessment of hs-CRP level is beneficial to predict the risk for future cardiovascular disease event and facilitate the management of obesity in this population. A prospective clinical study is recommended to confirm the findings.
format Article
author Shahadan, Siti Zuhaidah
Daud, Azlina
Md. Isa, Muhammad Lokman
Mohd Rasani, Ali Aminuddin
Ibrahim, Muhammad
Draman, Samsul
author_facet Shahadan, Siti Zuhaidah
Daud, Azlina
Md. Isa, Muhammad Lokman
Mohd Rasani, Ali Aminuddin
Ibrahim, Muhammad
Draman, Samsul
author_sort Shahadan, Siti Zuhaidah
title Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia
title_short Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia
title_full Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia
title_fullStr Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia
title_full_unstemmed Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia
title_sort abdominal obesity and high-sensitivity c-reactive protein level among malay obese adults in kuantan, malaysia
publisher Kulliyyah (Faculty) of Medicine, International Islamic University Malaysia
publishDate 2018
url http://irep.iium.edu.my/58135/
http://irep.iium.edu.my/58135/
http://irep.iium.edu.my/58135/19/58135%20Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive.pdf
http://irep.iium.edu.my/58135/13/58135_Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive%20Protein%20Level_SCOPUS.pdf
http://irep.iium.edu.my/58135/25/58135_Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive%20Protein%20Level%20among%20Malay%20Obese%20Adults%20in%20Kuantan%2C%20Malaysia_WOS.pdf
first_indexed 2023-09-18T21:22:11Z
last_indexed 2023-09-18T21:22:11Z
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