Thymoquinone suppression of the human hepatocellular carcinoma cell growth involves inhibition of IL-8 expression, elevated levels of TRAIL receptors, oxidative stress and apoptosis
Hepatocellular carcinoma (HCC) is the fourth most common solid tumor worldwide. The chemokine interleukin-8 (IL-8) is overexpressed in HCC and is a potential target for therapy. Although the transcription factor NF-κB regulates IL-8 expression, and while thymoquinone (TQ; the most bioactive constitu...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
Springer US
2014
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/63263/ http://irep.iium.edu.my/63263/ http://irep.iium.edu.my/63263/ http://irep.iium.edu.my/63263/1/8129_Thymoquinone%20suppression%20of%20the%20human.pdf http://irep.iium.edu.my/63263/2/8129_Thymoquinone%20suppression%20of%20the%20human_SCOPUS.pdf |