Carotenoid pigments of red, green and brown macroalgae species as potential active pharmaceutical ingredients

Active Pharmaceutical Ingredient (API) is a substance used in a finished pharmaceutical product, intended to furnish pharmacological activity or contribute direct effect in the diagnosis, cure, mitigation, treatment or prevention of disease. It also provides a direct effect in restoring, correcting...

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Main Authors:	Othman, Rashidi, Md Amin, Nur Alifah, Abu Bakar, Ainaa Eliah, Ahmad Fadzlillah, Nurrulhidayah, Mahmad, Noraini
Format:	Article
Language:	English
Published:	SET Publisher 2019
Subjects:	RS Pharmacy and materia medica S Agriculture (General) SB Plant culture TP248.13 Biotechnology TP934 Paints, pigments, varnishes, etc
Online Access:	http://irep.iium.edu.my/69532/ http://irep.iium.edu.my/69532/ http://irep.iium.edu.my/69532/1/69532_Carotenoid%20pigments%20of%20red%2C%20green%20and%20brown.pdf

id	iium-69532
recordtype	eprints
spelling	iium-695322019-07-12T07:29:15Z http://irep.iium.edu.my/69532/ Carotenoid pigments of red, green and brown macroalgae species as potential active pharmaceutical ingredients Othman, Rashidi Md Amin, Nur Alifah Abu Bakar, Ainaa Eliah Ahmad Fadzlillah, Nurrulhidayah Mahmad, Noraini RS Pharmacy and materia medica S Agriculture (General) SB Plant culture TP248.13 Biotechnology TP934 Paints, pigments, varnishes, etc Active Pharmaceutical Ingredient (API) is a substance used in a finished pharmaceutical product, intended to furnish pharmacological activity or contribute direct effect in the diagnosis, cure, mitigation, treatment or prevention of disease. It also provides a direct effect in restoring, correcting or modifying physiological functions in human beings. Macroalgae, also known as seaweed, are plant-like organisms that can be found in a marine habitat. Macroalgae has been given huge concern because of its high nutritional value and short-term growth, which is only 45 days per cycle. Therefore, three red macroalgae species of Eucheuma denticulatum, Gracilaria tikvahiae and Kappaphycus striatum), as well as green and brown macroalgae species of Caulerpa lentillifera and Padina pavonica were selected to determine their carotenoids content and composition by using UV-Vis spectrophotometer and HPLC analysis. The main carotenoids identified in red, green and brown macroalgae species were zeaxanthin, lutein, β-carotene and violaxanthin. Marked differences were observed between red, green and brown macroalgae carotenoids content and composition. Zeaxanthin and β-carotene were detected in all red, green and brown macroalgae ranged from 3.61 to 21.30 μg/g DW and 2.44 to 10.70 μg/g DW respectively. Violaxanthin was found only in green macroalgae (8.93 μg/g DW) whereas lutein was found only in red macroalgae (9.57 to 38.60 μg/g DW). In terms of total carotenoid content, green macroalgae contained the highest amount of carotenoid (100.89 ± 14.71 μg/g DW). The significant outcome of the research will be new natural carotenoid pigment sources as potential active pharmaceutical ingredients which can be beneficial to halal health-promoting products industry. SET Publisher 2019-01 Article PeerReviewed application/pdf en http://irep.iium.edu.my/69532/1/69532_Carotenoid%20pigments%20of%20red%2C%20green%20and%20brown.pdf Othman, Rashidi and Md Amin, Nur Alifah and Abu Bakar, Ainaa Eliah and Ahmad Fadzlillah, Nurrulhidayah and Mahmad, Noraini (2019) Carotenoid pigments of red, green and brown macroalgae species as potential active pharmaceutical ingredients. Journal of Pharmacy and Nutrition Sciences, 9 (1). pp. 14-19. ISSN 2223-3806 E-ISSN 1927-5951 http://setpublisher.com/downloads/jpansv9n1a3/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RS Pharmacy and materia medica S Agriculture (General) SB Plant culture TP248.13 Biotechnology TP934 Paints, pigments, varnishes, etc
spellingShingle	RS Pharmacy and materia medica S Agriculture (General) SB Plant culture TP248.13 Biotechnology TP934 Paints, pigments, varnishes, etc Othman, Rashidi Md Amin, Nur Alifah Abu Bakar, Ainaa Eliah Ahmad Fadzlillah, Nurrulhidayah Mahmad, Noraini Carotenoid pigments of red, green and brown macroalgae species as potential active pharmaceutical ingredients
description	Active Pharmaceutical Ingredient (API) is a substance used in a finished pharmaceutical product, intended to furnish pharmacological activity or contribute direct effect in the diagnosis, cure, mitigation, treatment or prevention of disease. It also provides a direct effect in restoring, correcting or modifying physiological functions in human beings. Macroalgae, also known as seaweed, are plant-like organisms that can be found in a marine habitat. Macroalgae has been given huge concern because of its high nutritional value and short-term growth, which is only 45 days per cycle. Therefore, three red macroalgae species of Eucheuma denticulatum, Gracilaria tikvahiae and Kappaphycus striatum), as well as green and brown macroalgae species of Caulerpa lentillifera and Padina pavonica were selected to determine their carotenoids content and composition by using UV-Vis spectrophotometer and HPLC analysis. The main carotenoids identified in red, green and brown macroalgae species were zeaxanthin, lutein, β-carotene and violaxanthin. Marked differences were observed between red, green and brown macroalgae carotenoids content and composition. Zeaxanthin and β-carotene were detected in all red, green and brown macroalgae ranged from 3.61 to 21.30 μg/g DW and 2.44 to 10.70 μg/g DW respectively. Violaxanthin was found only in green macroalgae (8.93 μg/g DW) whereas lutein was found only in red macroalgae (9.57 to 38.60 μg/g DW). In terms of total carotenoid content, green macroalgae contained the highest amount of carotenoid (100.89 ± 14.71 μg/g DW). The significant outcome of the research will be new natural carotenoid pigment sources as potential active pharmaceutical ingredients which can be beneficial to halal health-promoting products industry.
format	Article
author	Othman, Rashidi Md Amin, Nur Alifah Abu Bakar, Ainaa Eliah Ahmad Fadzlillah, Nurrulhidayah Mahmad, Noraini
author_facet	Othman, Rashidi Md Amin, Nur Alifah Abu Bakar, Ainaa Eliah Ahmad Fadzlillah, Nurrulhidayah Mahmad, Noraini
author_sort	Othman, Rashidi
title	Carotenoid pigments of red, green and brown macroalgae species as potential active pharmaceutical ingredients
title_short	Carotenoid pigments of red, green and brown macroalgae species as potential active pharmaceutical ingredients
title_full	Carotenoid pigments of red, green and brown macroalgae species as potential active pharmaceutical ingredients
title_fullStr	Carotenoid pigments of red, green and brown macroalgae species as potential active pharmaceutical ingredients
title_full_unstemmed	Carotenoid pigments of red, green and brown macroalgae species as potential active pharmaceutical ingredients
title_sort	carotenoid pigments of red, green and brown macroalgae species as potential active pharmaceutical ingredients
publisher	SET Publisher
publishDate	2019
url	http://irep.iium.edu.my/69532/ http://irep.iium.edu.my/69532/ http://irep.iium.edu.my/69532/1/69532_Carotenoid%20pigments%20of%20red%2C%20green%20and%20brown.pdf
first_indexed	2023-09-18T21:38:42Z
last_indexed	2023-09-18T21:38:42Z
_version_	1777412994388459520

Carotenoid pigments of red, green and brown macroalgae species as potential active pharmaceutical ingredients

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