Anti-diabetic potential of peptide from P. niruri reveals through carbohydrate hydrolyzing enzyme inhibition assay
Herb Phyllanthus niruri (P. niruri) is known to have various pharmacological functions including anti-diabetic properties. In this research, protein extracts from different plant parts (leave, fruit and stem) of P. niruri were investigated for their anti-diabetic potential through α-amylase and α-...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Zebline International Publishing
2019
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/70806/ http://irep.iium.edu.my/70806/ http://irep.iium.edu.my/70806/ http://irep.iium.edu.my/70806/1/70806_Anti-diabetic%20potential%20of%20peptide%20from%20P.%20niruri.pdf |
| Summary: | Herb Phyllanthus niruri (P. niruri) is known to have various pharmacological functions including anti-diabetic
properties. In this research, protein extracts from different plant parts (leave, fruit and stem) of P. niruri were
investigated for their anti-diabetic potential through α-amylase and α-glucosidase enzyme inhibition assays. For the
enzyme inhibition assay, fruit was found to have the highest inhibition percentage (90.0%) against α-glucosidase
followed by leave (62.6%) and stem (38.4%). The similar patterns were also recorded for the α-amylase enzyme
inhibition assay, in which, fruit showed the highest inhibition percentage (64.1%) followed by leave (33.3%) and
stem (18.2%). The findings of this research suggest that fruit of P. niruri is a potential plant part with regards to antidiabetic
properties since it exhibits the highest inhibition activity against both α-amylase and α-glucosidase enzyme
compared to leave and stem. |
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